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    Dqx1 DEAQ RNA-dependent ATPase [ Mus musculus (house mouse) ]

    Gene ID: 93838, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Dqx1provided by MGI
    Official Full Name
    DEAQ RNA-dependent ATPaseprovided by MGI
    Primary source
    MGI:MGI:2136388
    See related
    Ensembl:ENSMUSG00000009145 AllianceGenome:MGI:2136388
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2310066E11Rik
    Summary
    Predicted to enable ATP hydrolysis activity; RNA binding activity; and helicase activity. Predicted to be involved in DNA duplex unwinding; chromatin looping; and chromatin remodeling. Predicted to be located in nucleus. Predicted to be part of spliceosomal complex. Is expressed in thymus primordium. Orthologous to human DQX1 (DEAQ-box RNA dependent ATPase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in duodenum adult (RPKM 21.5), large intestine adult (RPKM 21.4) and 16 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Dqx1 in Genome Data Viewer
    Location:
    6 C3; 6 35.94 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (83034728..83044294)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (83057747..83067313)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene lysyl oxidase-like 3 Neighboring gene microRNA 7040 Neighboring gene STARR-positive B cell enhancer ABC_E9275 Neighboring gene HtrA serine peptidase 2 Neighboring gene ancient ubiquitous protein 1 Neighboring gene T cell leukemia, homeobox 2 Neighboring gene polycomb group ring finger 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. DQX1, an RNA-dependent ATPase homolog with a novel DEAQ box: expression pattern and genomic sequence comparison of the human and mouse genes. Ji W, et al. Mamm Genome, 2001 Jun. PMID 11353393
    2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    enables ATP-dependent H2AZ histone chaperone activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP-dependent H3-H4 histone complex chaperone activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA clamp loader activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables chromatin extrusion motor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cohesin loader activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables double-stranded DNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables forked DNA-dependent helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables four-way junction helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables helicase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables single-stranded 3'-5' DNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA duplex unwinding IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in chromatin looping IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    ATP-dependent RNA helicase DQX1
    Names
    DEAQ box polypeptide 1
    NP_291084.1
    XP_006506870.1
    XP_006506871.1
    XP_006506872.1
    XP_006506873.1
    XP_006506874.1
    XP_036008306.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_033606.3 → NP_291084.1  ATP-dependent RNA helicase DQX1

      See identical proteins and their annotated locations for NP_291084.1

      Status: PROVISIONAL

      Source sequence(s)
      AC104324
      Consensus CDS
      CCDS20268.1
      UniProtKB/Swiss-Prot
      Q80ZJ5, Q924H9
      Related
      ENSMUSP00000076708.3, ENSMUST00000077502.5
      Conserved Domains (1) summary
      COG1643
      Location:9 → 672
      HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      83034728..83044294
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006506808.3 → XP_006506871.1  ATP-dependent RNA helicase DQX1 isoform X1

      See identical proteins and their annotated locations for XP_006506871.1

      UniProtKB/Swiss-Prot
      Q80ZJ5, Q924H9
      Conserved Domains (1) summary
      COG1643
      Location:9 → 672
      HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]

    2. XM_006506810.5 → XP_006506873.1  ATP-dependent RNA helicase DQX1 isoform X2

      Conserved Domains (1) summary
      COG1643
      Location:9 → 648
      HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]

    3. XM_006506807.5 → XP_006506870.1  ATP-dependent RNA helicase DQX1 isoform X1

      See identical proteins and their annotated locations for XP_006506870.1

      UniProtKB/Swiss-Prot
      Q80ZJ5, Q924H9
      Conserved Domains (1) summary
      COG1643
      Location:9 → 672
      HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]

    4. XM_006506811.5 → XP_006506874.1  ATP-dependent RNA helicase DQX1 isoform X3

      Conserved Domains (1) summary
      COG1643
      Location:1 → 567
      HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]

    5. XM_036152413.1 → XP_036008306.1  ATP-dependent RNA helicase DQX1 isoform X4

      Conserved Domains (1) summary
      COG1643
      Location:8 → 390
      HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]

    6. XM_006506809.2 → XP_006506872.1  ATP-dependent RNA helicase DQX1 isoform X1

      See identical proteins and their annotated locations for XP_006506872.1

      UniProtKB/Swiss-Prot
      Q80ZJ5, Q924H9
      Conserved Domains (1) summary
      COG1643
      Location:9 → 672
      HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]

    RNA

    1. XR_004933648.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q924H9.1 GenPept UniProtKB/Swiss-Prot:Q924H9

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