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    PLEKHG2 pleckstrin homology and RhoGEF domain containing G2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 698408, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PLEKHG2provided by VGNC
    Official Full Name
    pleckstrin homology and RhoGEF domain containing G2provided by VGNC
    Primary source
    VGNC:VGNC:76133
    See related
    Ensembl:ENSMMUG00000019369
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PLEKHG2 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 19 NC_041772.1 (38664352..38679679)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 19 NC_027911.1 (35160578..35175953)

    Chromosome 19 - NC_041772.1Genomic Context describing neighboring genes Neighboring gene ZFP36 ring finger protein Neighboring gene transfer RNA isoleucine (anticodon UAU) Neighboring gene uncharacterized LOC114674098 Neighboring gene ribosomal protein S16

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pleckstrin homology domain-containing family G member 2
    Names
    pleckstrin homology domain containing, family G (with RhoGef domain) member 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041772.1 Reference Mmul_10 Primary Assembly

      Range
      38664352..38679679
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015123907.2 → XP_014979393.2  pleckstrin homology domain-containing family G member 2 isoform X1

      UniProtKB/TrEMBL
      F6T9Q6
      Conserved Domains (5) summary
      PHA03247
      Location:442 → 906
      PHA03247; large tegument protein UL36; Provisional
      cd13243
      Location:264 → 414
      PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00621
      Location:107 → 282
      RhoGEF; RhoGEF domain
      pfam09770
      Location:737 → 995
      PAT1; Topoisomerase II-associated protein PAT1
      pfam03154
      Location:913 → 1241
      Atrophin-1; Atrophin-1 family

    2. XM_015123908.2 → XP_014979394.2  pleckstrin homology domain-containing family G member 2 isoform X2

      UniProtKB/TrEMBL
      A0A1D5QZZ9, F6T9Q6
      Related
      ENSMMUP00000053632.2, ENSMMUT00000073731.2
      Conserved Domains (4) summary
      PTZ00449
      Location:485 → 691
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      PHA03247
      Location:673 → 1238
      PHA03247; large tegument protein UL36; Provisional
      cd13243
      Location:263 → 413
      PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00621
      Location:106 → 281
      RhoGEF; RhoGEF domain

    3. XM_028839539.1 → XP_028695372.1  pleckstrin homology domain-containing family G member 2 isoform X2

      UniProtKB/TrEMBL
      A0A1D5QZZ9, F6T9Q6
      Conserved Domains (4) summary
      PTZ00449
      Location:485 → 691
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      PHA03247
      Location:673 → 1238
      PHA03247; large tegument protein UL36; Provisional
      cd13243
      Location:263 → 413
      PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00621
      Location:106 → 281
      RhoGEF; RhoGEF domain

    4. XM_028839537.1 → XP_028695370.1  pleckstrin homology domain-containing family G member 2 isoform X1

      UniProtKB/TrEMBL
      F6T9Q6
      Conserved Domains (5) summary
      PHA03247
      Location:442 → 906
      PHA03247; large tegument protein UL36; Provisional
      cd13243
      Location:264 → 414
      PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00621
      Location:107 → 282
      RhoGEF; RhoGEF domain
      pfam09770
      Location:737 → 995
      PAT1; Topoisomerase II-associated protein PAT1
      pfam03154
      Location:913 → 1241
      Atrophin-1; Atrophin-1 family

    5. XM_028839543.1 → XP_028695376.1  pleckstrin homology domain-containing family G member 2 isoform X5

      UniProtKB/TrEMBL
      F6T9Q6
      Conserved Domains (3) summary
      PHA03247
      Location:614 → 1179
      PHA03247; large tegument protein UL36; Provisional
      cd13243
      Location:204 → 354
      PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00621
      Location:47 → 222
      RhoGEF; RhoGEF domain

    6. XM_028839540.1 → XP_028695373.1  pleckstrin homology domain-containing family G member 2 isoform X2

      UniProtKB/TrEMBL
      A0A1D5QZZ9, F6T9Q6
      Conserved Domains (4) summary
      PTZ00449
      Location:485 → 691
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      PHA03247
      Location:673 → 1238
      PHA03247; large tegument protein UL36; Provisional
      cd13243
      Location:263 → 413
      PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00621
      Location:106 → 281
      RhoGEF; RhoGEF domain

    7. XM_028839542.1 → XP_028695375.1  pleckstrin homology domain-containing family G member 2 isoform X4

      UniProtKB/TrEMBL
      F6T9Q6
      Conserved Domains (5) summary
      PTZ00449
      Location:510 → 663
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      cd13243
      Location:264 → 414
      PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00621
      Location:107 → 282
      RhoGEF; RhoGEF domain
      pfam09770
      Location:708 → 966
      PAT1; Topoisomerase II-associated protein PAT1
      pfam03154
      Location:884 → 1212
      Atrophin-1; Atrophin-1 family

    8. XM_028839538.1 → XP_028695371.1  pleckstrin homology domain-containing family G member 2 isoform X1

      UniProtKB/TrEMBL
      F6T9Q6
      Conserved Domains (5) summary
      PHA03247
      Location:442 → 906
      PHA03247; large tegument protein UL36; Provisional
      cd13243
      Location:264 → 414
      PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00621
      Location:107 → 282
      RhoGEF; RhoGEF domain
      pfam09770
      Location:737 → 995
      PAT1; Topoisomerase II-associated protein PAT1
      pfam03154
      Location:913 → 1241
      Atrophin-1; Atrophin-1 family

    9. XM_028839536.1 → XP_028695369.1  pleckstrin homology domain-containing family G member 2 isoform X1

      UniProtKB/TrEMBL
      F6T9Q6
      Conserved Domains (5) summary
      PHA03247
      Location:442 → 906
      PHA03247; large tegument protein UL36; Provisional
      cd13243
      Location:264 → 414
      PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00621
      Location:107 → 282
      RhoGEF; RhoGEF domain
      pfam09770
      Location:737 → 995
      PAT1; Topoisomerase II-associated protein PAT1
      pfam03154
      Location:913 → 1241
      Atrophin-1; Atrophin-1 family

    10. XM_028839541.1 → XP_028695374.1  pleckstrin homology domain-containing family G member 2 isoform X3

      UniProtKB/TrEMBL
      A0A1D5RHC0, F6T9Q6
      Related
      ENSMMUP00000059714.2, ENSMMUT00000066834.2
      Conserved Domains (4) summary
      PHA03247
      Location:440 → 797
      PHA03247; large tegument protein UL36; Provisional
      cd13243
      Location:264 → 414
      PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00621
      Location:107 → 282
      RhoGEF; RhoGEF domain
      pfam03154
      Location:900 → 1228
      Atrophin-1; Atrophin-1 family
    Nucleotide Protein
    Heading Accession and Version

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