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    RHEB Ras homolog, mTORC1 binding [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 715378, updated on 5-Mar-2024

    Summary

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    Gene symbol
    RHEB
    Gene description
    Ras homolog, mTORC1 binding
    See related
    Ensembl:ENSMMUG00000051076
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See RHEB in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (177465325..177517200, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (177688401..177741716, complement)

    Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene negative regulator of ubiquitin like proteins 1 Neighboring gene WD repeat domain 86 Neighboring gene uncharacterized LOC114677069 Neighboring gene crystallin gamma N Neighboring gene eukaryotic peptide chain release factor subunit 1 pseudogene Neighboring gene uncharacterized LOC114677071 Neighboring gene protein kinase AMP-activated non-catalytic subunit gamma 2 Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GDP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in small GTPase-mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    GTP-binding protein Rheb
    Names
    Ras homolog enriched in brain
    NP_001248111.1
    XP_028700881.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001261182.1 → NP_001248111.1  GTP-binding protein Rheb

      See identical proteins and their annotated locations for NP_001248111.1

      Status: PROVISIONAL

      Source sequence(s)
      JV047844
      UniProtKB/TrEMBL
      F7H5C5, G7MNH9
      Related
      ENSMMUP00000079430.1, ENSMMUT00000082593.1
      Conserved Domains (1) summary
      cd04137
      Location:6 → 184
      RheB; Ras Homolog Enriched in Brain (RheB) is a small GTPase

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041756.1 Reference Mmul_10 Primary Assembly

      Range
      177465325..177517200 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028845048.1 → XP_028700881.1  GTP-binding protein Rheb isoform X1

      UniProtKB/TrEMBL
      G7MNH9
      Conserved Domains (1) summary
      cd04137
      Location:13 → 181
      RheB; Ras Homolog Enriched in Brain (RheB) is a small GTPase
    Nucleotide Protein
    Heading Accession and Version

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