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    Nup62cl nucleoporin 62 C-terminal like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 300923, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Nup62clprovided by RGD
    Official Full Name
    nucleoporin 62 C-terminal likeprovided by RGD
    Primary source
    RGD:1564353
    See related
    EnsemblRapid:ENSRNOG00000057753 AllianceGenome:RGD:1564353
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1564353
    Summary
    Predicted to enable phospholipid binding activity. Predicted to be a structural constituent of nuclear pore. Predicted to be involved in RNA export from nucleus and protein import into nucleus. Predicted to be part of nuclear pore central transport channel. Orthologous to human NUP62CL (nucleoporin 62 C-terminal like). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Testes (RPKM 24.8), Lung (RPKM 4.6) and 1 other tissue See more
    Orthologs
    human mouse all
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    Genomic context

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    See Nup62cl in Genome Data Viewer
    Location:
    Xq32
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (108457043..108513525, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (103668458..103724957, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (111333274..111390023, complement)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene protein kinase C and casein kinase substrate in neurons 2, pseudogene 1 Neighboring gene RNA binding motif protein 41 Neighboring gene dynein axonemal assembly factor 6 Neighboring gene small nucleolar RNA SNORA48 Neighboring gene FERM and PDZ domain containing 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The mammalian RNA-binding protein Staufen2 links nuclear and cytoplasmic RNA processing pathways in neurons. Monshausen M, et al. Neuromolecular Med, 2004. PMID 15970630
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables phospholipid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of nuclear pore IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein import into nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of nuclear pore central transport channel IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    nucleoporin-62 C-terminal-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427605.1 → NP_001414534.1  nucleoporin-62 C-terminal-like protein

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000021
      UniProtKB/TrEMBL
      A0A0G2KB27, A6HLS3
      Related
      ENSRNOP00000075626.1, ENSRNOT00000088979.3

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      108457043..108513525 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006234255.5 → XP_006234317.1  nucleoporin-62 C-terminal-like protein isoform X1

      See identical proteins and their annotated locations for XP_006234317.1

      UniProtKB/TrEMBL
      A0A0G2KB27, A6HLS3
      Conserved Domains (1) summary
      pfam05064
      Location:66 → 180
      Nsp1_C; Nsp1-like C-terminal region

    2. XM_006234254.5 → XP_006234316.1  nucleoporin-62 C-terminal-like protein isoform X1

      See identical proteins and their annotated locations for XP_006234316.1

      UniProtKB/TrEMBL
      A0A0G2KB27, A6HLS3
      Conserved Domains (1) summary
      pfam05064
      Location:66 → 180
      Nsp1_C; Nsp1-like C-terminal region

    3. XM_039100269.2 → XP_038956197.1  nucleoporin-62 C-terminal-like protein isoform X1

      UniProtKB/TrEMBL
      A0A0G2KB27, A6HLS3
      Conserved Domains (1) summary
      pfam05064
      Location:66 → 180
      Nsp1_C; Nsp1-like C-terminal region
    Nucleotide Protein Strain
    Heading Accession and Version

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