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    Wdr5b WD repeat domain 5B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 303907, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Wdr5bprovided by RGD
    Official Full Name
    WD repeat domain 5Bprovided by RGD
    Primary source
    RGD:1308567
    See related
    EnsemblRapid:ENSRNOG00000002253 AllianceGenome:RGD:1308567
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable histone binding activity. Predicted to be part of Set1C/COMPASS complex. Orthologous to human WDR5B (WD repeat domain 5B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See Wdr5b in Genome Data Viewer
    Location:
    11q22
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (78216266..78218125, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (64710945..64712804, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (67645959..67647818, complement)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134481076 Neighboring gene RAN binding protein 1 like 1 Neighboring gene mitochondrial matrix import factor 23 Neighboring gene family with sequence similarity 162, member A Neighboring gene karyopherin subunit alpha 1 Neighboring gene uncharacterized LOC134481077 Neighboring gene poly (ADP-ribose) polymerase family, member 9 Neighboring gene deltex E3 ubiquitin ligase 3L

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. PERIOD1-associated proteins modulate the negative limb of the mammalian circadian oscillator. Brown SA, et al. Science, 2005 Apr 29. PMID 15860628
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Set1C/COMPASS complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    WD repeat-containing protein 5B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024766.1 → NP_001019937.1  WD repeat-containing protein 5B

      See identical proteins and their annotated locations for NP_001019937.1

      Status: PROVISIONAL

      Source sequence(s)
      BC097449
      UniProtKB/Swiss-Prot
      Q4V8C4
      UniProtKB/TrEMBL
      A6IRE4
      Related
      ENSRNOP00000003068.2, ENSRNOT00000003068.5
      Conserved Domains (2) summary
      cd00200
      Location:31 → 325
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:42 → 79
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      78216266..78218125 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4V8C4.1 GenPept UniProtKB/Swiss-Prot:Q4V8C4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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