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    ik IK cytokine [ Danio rerio (zebrafish) ]

    Gene ID: 322241, updated on 9-Dec-2024

    Summary

    Official Symbol
    ikprovided by ZNC
    Official Full Name
    IK cytokineprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-960
    See related
    Ensembl:ENSDARG00000004161 AllianceGenome:ZFIN:ZDB-GENE-030131-960
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:56500; wu:fb54c03
    Summary
    Acts upstream of or within heart contraction; mRNA splicing, via spliceosome; and skeletal muscle fiber development. Predicted to be active in nucleus. Is expressed in central nervous system; gut; and pharyngeal arch 3-7 skeleton. Orthologous to human IK (IK cytokine). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    Location:
    chromosome: 21
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (44013487..44037107)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (44018321..44041941)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103909492 Neighboring gene NADH:ubiquinone oxidoreductase subunit A2 Neighboring gene arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 Neighboring gene organic anion transporter X

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein Red
    Names
    IK cytokine, down-regulator of HLA II

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199589.1NP_955883.1  protein Red

      See identical proteins and their annotated locations for NP_955883.1

      Status: PROVISIONAL

      Source sequence(s)
      BC049322
      UniProtKB/TrEMBL
      A0A8M1PE52, F6P0P4, Q860B9
      Related
      ENSDARP00000009186.8, ENSDART00000012396.9
      Conserved Domains (2) summary
      pfam07807
      Location:436545
      RED_C; RED-like protein C-terminal region
      pfam07808
      Location:83295
      RED_N; RED-like protein N-terminal region

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      44013487..44037107
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068215781.1XP_068071882.1  protein Red isoform X1

      UniProtKB/TrEMBL
      A0A8M1PE52, F6P0P4, Q860B9