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    edf1 endothelial differentiation-related factor 1 [ Danio rerio (zebrafish) ]

    Gene ID: 793036, updated on 9-Dec-2024

    Summary

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    Official Symbol
    edf1provided by ZNC
    Official Full Name
    endothelial differentiation-related factor 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1710
    See related
    Ensembl:ENSDARG00000009950 AllianceGenome:ZFIN:ZDB-GENE-040426-1710
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:73192; zgc:86829
    Summary
    Predicted to enable DNA binding activity. Predicted to be active in nucleus. Orthologous to human EDF1 (endothelial differentiation related factor 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See edf1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (64397643..64406058)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (63716479..63724894)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103911142 Neighboring gene phospholipid phosphatase 7a (inactive) Neighboring gene BRD3 opposite strand Neighboring gene bromodomain containing 3b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC73192, MGC86829

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    endothelial differentiation-related factor 1 homolog
    Names
    EDF-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200745.1 → NP_957039.1  endothelial differentiation-related factor 1 homolog

      See identical proteins and their annotated locations for NP_957039.1

      Status: PROVISIONAL

      Source sequence(s)
      BC059541
      UniProtKB/Swiss-Prot
      Q6PBY3
      UniProtKB/TrEMBL
      A5PN46
      Related
      ENSDARP00000026769.5, ENSDART00000015940.7
      Conserved Domains (2) summary
      smart00530
      Location:80 → 132
      HTH_XRE; Helix-turn-helix XRE-family like proteins
      pfam08523
      Location:4 → 71
      MBF1; Multiprotein bridging factor 1

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      64397643..64406058
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6PBY3.1 GenPept UniProtKB/Swiss-Prot:Q6PBY3

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