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    zgc:112271 zgc:112271 [ Danio rerio (zebrafish) ]

    Gene ID: 553698, updated on 9-Dec-2024

    Summary

    Official Symbol
    zgc:112271provided by ZNC
    Official Full Name
    zgc:112271provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050522-443
    See related
    Ensembl:ENSDARG00000111714 AllianceGenome:ZFIN:ZDB-GENE-050522-443
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to enable iron-sulfur cluster binding activity. Predicted to be involved in intracellular iron ion homeostasis. Predicted to act upstream of or within protein maturation by iron-sulfur cluster transfer. Predicted to be active in cytosol and nucleus. Orthologous to human BOLA2 (bolA family member 2) and BOLA2B (bolA family member 2B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See zgc:112271 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (59554785..59563755, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (59251573..59258445, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) Unplaced Scaffold NW_008805376.1 (810..981)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F Neighboring gene SLX1 homolog B, structure-specific endonuclease subunit Neighboring gene La ribonucleoprotein 7, transcriptional regulator Neighboring gene ribosomal protein L34

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Clone Names

    • MGC112271

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables 2 iron, 2 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables iron-sulfur cluster binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in intracellular iron ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within protein maturation by iron-sulfur cluster transfer IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein LOC553698
    Names
    bolA-like protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001243171.1NP_001230100.1  uncharacterized protein LOC553698

      See identical proteins and their annotated locations for NP_001230100.1

      Status: VALIDATED

      Source sequence(s)
      EH555052, EH592627
      UniProtKB/TrEMBL
      A0A8M1NYQ9, Q502F6
      Related
      ENSDARP00000146412.1, ENSDART00000186053.1
      Conserved Domains (1) summary
      pfam01722
      Location:1279
      BolA; BolA-like protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      59554785..59563755 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)