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    ZK563.2 Sodium-dependent phosphate transport protein 2B [ Caenorhabditis elegans ]

    Gene ID: 191351, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ZK563.2
    Official Full Name
    Sodium-dependent phosphate transport protein 2B
    Primary source
    WormBase:WBGene00022767
    Locus tag
    CELE_ZK563.2
    See related
    AllianceGenome:WB:WBGene00022767
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable sodium:phosphate symporter activity. Predicted to be involved in sodium ion transmembrane transport and sodium-dependent phosphate transport. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Fanconi syndrome (multiple); chronic kidney disease; hereditary hypophosphatemic rickets with hypercalciuria; hypophosphatemic nephrolithiasis/osteoporosis 1; and pulmonary alveolar microlithiasis. Orthologous to several human genes including SLC34A2 (solute carrier family 34 member 2) and SLC34A3 (solute carrier family 34 member 3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ZK563.2 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    12
    Sequence:
    Chromosome: X; NC_003284.9 (3368959..3373296)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene DUF3301 domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene DeHydrogenases, Short chain Neighboring gene tRNA-Thr Neighboring gene ncRNA Neighboring gene CLaudin-like in Caenorhabditis Neighboring gene ncRNA Neighboring gene Suppressor of organelle fusion 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables sodium:phosphate symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in sodium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sodium-dependent phosphate transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Sodium-dependent phosphate transport protein 2B
    NP_001361929.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      3368959..3373296
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001374992.2 → NP_001361929.1  Sodium-dependent phosphate transport protein 2B [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q23530
      Conserved Domains (1) summary
      TIGR01013
      Location:74 → 533
      2a58; Phosphate:Na+ Symporter (PNaS) Family
    Nucleotide Protein
    Heading Accession and Version

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