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Conserved domains on  [gi|1767287022|ref|NP_001361929|]
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Sodium-dependent phosphate transport protein 2B [Caenorhabditis elegans]

Protein Classification

sodium-dependent phosphate transport protein 2( domain architecture ID 11490082)

sodium-dependent phosphate transport protein 2 may be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
2a58 TIGR01013
Phosphate:Na+ Symporter (PNaS) Family; [Transport and binding proteins, Cations and iron ...
74-533 9.12e-146

Phosphate:Na+ Symporter (PNaS) Family; [Transport and binding proteins, Cations and iron carrying compounds]


:

Pssm-ID: 162157 [Multi-domain]  Cd Length: 456  Bit Score: 428.90  E-value: 9.12e-146
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022  74 YVCSLANMSTAFGLLGSRGLGKAIQESPLINDPISAVVVGMLATVVLQSATTTTNILVTMVAANMITVHDAIPVMIGSEL 153
Cdd:TIGR01013   7 FVCSLAVLSAAFILLGAKVGGAIFADILITDNPWASPLLGFLGTVLLQSSSTSRSIVVGMVSAGLLLVLLAIPLIMGANI 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022 154 GSSLVNAMVSLAYSGKPEQFRRAFSAAILGDVFNVCGLFVIFPMEMFTGLIEKVSWWIVDPLISEQG-LSFKTLELLTDP 232
Cdd:TIGR01013  87 GSSVTNAIVAIMQSGDRAWFRRAFIGATVADIFNSSLALVLLPLELTTGGIESVTLLVVLVFGANGGgDAPDLLNSLTAP 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022 233 INQVILQvneveLLNATIRPEMFEANHSFVQRCSFTNG----TRIYNCPYNHLFShtslsdkNIGWIVLFVSIFCLVMCL 308
Cdd:TIGR01013 167 ATALIVQ-----LDNLIIRLIGSLLILPLIDILASTLSslpvPESNLPIEAHIFV-------NVGLILLALPFVRLCARL 234
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022 309 VGIVYLIQKLLDGHAANYVRNLLSKQCPGMWKPCTGYLVMLVGLVVTILIQSNSIFSSSLTPLVGSGVVTLEQMYPLVLG 388
Cdd:TIGR01013 235 ILVVIPLNSLLDGQVAPVILDVINLDTPVPFLWVTGYEALLVGDAMTFIIQSSSVFTSALTPLVGKGVISLERAYPLVLG 314
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022 389 SNIGTTFSGVLAAFSTDPSRFEKALHMAMCQVIYNIIGTCLFYIVPCTRKfPVYLSVKLGVITDHYRWFIVVFISTVFLI 468
Cdd:TIGR01013 315 SNIGTTLTAVLAALLSEDEKRRSALQIAYCHNLFNISGIVLFYPLPCTRK-PIAAARGFGDDGSKYRWFLIVYLVLNFLL 393
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1767287022 469 IPFTIIGLTLLPDNVIVIVFIIILIIAITCCFICVLQNSCKEflPKILHNWSFLPIWMRSLQYYD 533
Cdd:TIGR01013 394 APSLLFGLDLNLARRLVGVKIPFRILELFSSLLHVLQLRCPR--PQSLQTWSFLPDWLRSLKRLD 456
 
Name Accession Description Interval E-value
2a58 TIGR01013
Phosphate:Na+ Symporter (PNaS) Family; [Transport and binding proteins, Cations and iron ...
74-533 9.12e-146

Phosphate:Na+ Symporter (PNaS) Family; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 162157 [Multi-domain]  Cd Length: 456  Bit Score: 428.90  E-value: 9.12e-146
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022  74 YVCSLANMSTAFGLLGSRGLGKAIQESPLINDPISAVVVGMLATVVLQSATTTTNILVTMVAANMITVHDAIPVMIGSEL 153
Cdd:TIGR01013   7 FVCSLAVLSAAFILLGAKVGGAIFADILITDNPWASPLLGFLGTVLLQSSSTSRSIVVGMVSAGLLLVLLAIPLIMGANI 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022 154 GSSLVNAMVSLAYSGKPEQFRRAFSAAILGDVFNVCGLFVIFPMEMFTGLIEKVSWWIVDPLISEQG-LSFKTLELLTDP 232
Cdd:TIGR01013  87 GSSVTNAIVAIMQSGDRAWFRRAFIGATVADIFNSSLALVLLPLELTTGGIESVTLLVVLVFGANGGgDAPDLLNSLTAP 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022 233 INQVILQvneveLLNATIRPEMFEANHSFVQRCSFTNG----TRIYNCPYNHLFShtslsdkNIGWIVLFVSIFCLVMCL 308
Cdd:TIGR01013 167 ATALIVQ-----LDNLIIRLIGSLLILPLIDILASTLSslpvPESNLPIEAHIFV-------NVGLILLALPFVRLCARL 234
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022 309 VGIVYLIQKLLDGHAANYVRNLLSKQCPGMWKPCTGYLVMLVGLVVTILIQSNSIFSSSLTPLVGSGVVTLEQMYPLVLG 388
Cdd:TIGR01013 235 ILVVIPLNSLLDGQVAPVILDVINLDTPVPFLWVTGYEALLVGDAMTFIIQSSSVFTSALTPLVGKGVISLERAYPLVLG 314
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022 389 SNIGTTFSGVLAAFSTDPSRFEKALHMAMCQVIYNIIGTCLFYIVPCTRKfPVYLSVKLGVITDHYRWFIVVFISTVFLI 468
Cdd:TIGR01013 315 SNIGTTLTAVLAALLSEDEKRRSALQIAYCHNLFNISGIVLFYPLPCTRK-PIAAARGFGDDGSKYRWFLIVYLVLNFLL 393
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1767287022 469 IPFTIIGLTLLPDNVIVIVFIIILIIAITCCFICVLQNSCKEflPKILHNWSFLPIWMRSLQYYD 533
Cdd:TIGR01013 394 APSLLFGLDLNLARRLVGVKIPFRILELFSSLLHVLQLRCPR--PQSLQTWSFLPDWLRSLKRLD 456
NptA COG1283
Na+/phosphate symporter [Inorganic ion transport and metabolism];
106-472 2.85e-17

Na+/phosphate symporter [Inorganic ion transport and metabolism];


Pssm-ID: 440894 [Multi-domain]  Cd Length: 540  Bit Score: 84.85  E-value: 2.85e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022 106 PISAVVVGMLATVVLQSATTTTNILVTMVAANMITVHDAIPVMIGSELGSSLVNAMVSLAYSgkpeqfrrAFSAAILGdv 185
Cdd:COG1283    47 RLKGVLAGALVTALLQSSSATTVMVVGFVNAGLMTLAQALGVILGANIGTTLTAQLIAFDLS--------ALAPPLIA-- 116
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022 186 fnvCGLFVIFpmemftgliekvswwivdpliseqglsfktlelltdpinqvilqvnevellnatirpemfeanhsfvqrc 265
Cdd:COG1283   117 ---IGVILFL---------------------------------------------------------------------- 123
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022 266 sFTNGTRIyncpynhlfshtslsdKNIGWIVLFvsiFCLVmcLVGIVYLIQKLLDGHAANYVRNLLSKQCPGMWkpctgy 345
Cdd:COG1283   124 -FGKRRRL----------------RQIGRILIG---FGLL--FLGLDLMSEAMEPLRDSPAFRALLASLSGNPL------ 175
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022 346 LVMLVGLVVTILIQSNS----IFSSsltpLVGSGVVTLEQMYPLVLGSNIGTTFSGVLAAFSTDPSrfekALHMAMCQVI 421
Cdd:COG1283   176 LGVLVGALLTALVQSSSatvgLLLA----LAAQGLIPLEAALALVLGANIGTTITALLASIGANVA----ARRAALAHLL 247
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1767287022 422 YNIIGTCLFYIVpctrkFPVYLSVkLGVITDHYRWFIVVF-----ISTVFLIIPFT 472
Cdd:COG1283   248 FNLIGVLIFLPL-----LPPFAAL-VAWLSPDPARQIANFhtlfnLLNALLFLPFI 297
Na_Pi_cotrans pfam02690
Na+/Pi-cotransporter; This is a family of mainly mammalian type II renal Na+/Pi-cotransporters ...
81-164 7.84e-12

Na+/Pi-cotransporter; This is a family of mainly mammalian type II renal Na+/Pi-cotransporters with other related sequences from lower eukaryotes and bacteria some of which are also Na+/Pi-cotransporters. In the kidney the type II renal Na+/Pi-cotransporters protein allows re-absorption of filtered Pi in the proximal tubule.


Pssm-ID: 460653 [Multi-domain]  Cd Length: 137  Bit Score: 62.80  E-value: 7.84e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022  81 MSTAFGLLGSRGLGKAIQEspLINDPISAVVVGMLATVVLQSATTTTNILVTMVAANMITVHDAIPVMIGSELGSSLVNA 160
Cdd:pfam02690   9 MSDGLQKLAGGRLRRILEK--LTSNPLKGFLVGLLVTALLQSSSATTVMVVGFVNAGLLTLAQALGVIMGANIGTTVTAQ 86

                  ....
gi 1767287022 161 MVSL 164
Cdd:pfam02690  87 LIAF 90
Na_Pi_symport NF037997
Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) ...
345-472 1.68e-07

Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) superfamily.


Pssm-ID: 411591 [Multi-domain]  Cd Length: 294  Bit Score: 52.99  E-value: 1.68e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022 345 YLVMLVGLVVTILIQSNSIFSSSLTPLVGSGVVTLEQMYPLVLGSNIGTTFSGVLAAFSTDpsrfEKALHMAMCQVIYNI 424
Cdd:NF037997  165 LLALLIGTVLTAIIQSSSATTGITMSFLNEGILTLPAGIAIMLGANIGTCITALLASIGSG----KEAKLTAYAHIWLNV 240
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1767287022 425 IGTCLFY--IVPCTRkFPVYLSVKLGVITDHyrwFIVVF-ISTVFLIIPFT 472
Cdd:NF037997  241 LGVLLFLpfIHLLGE-FVALLASSPDVQLAH---ASVLFnVISSLLVLPFA 287
Na_Pi_symport NF037997
Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) ...
348-430 4.20e-06

Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) superfamily.


Pssm-ID: 411591 [Multi-domain]  Cd Length: 294  Bit Score: 48.75  E-value: 4.20e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022 348 MLVGLVVTILIQSNSIFSSSLTPLVGSGVVTLEQMYPLVLGSNIGTTFSGVLAAFSTD----PSRFEKALHMAMCQVIYN 423
Cdd:NF037997   42 FLTGTVITAILQSSSAVMVLTVGLVSAGILTFRQSIGIILGTNIGTTFTTEFITFDIDrliiPLLIIGALLLFLPRPALK 121

                  ....*..
gi 1767287022 424 IIGTCLF 430
Cdd:NF037997  122 SLGMSLF 128
Na_Pi_symport NF037997
Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) ...
76-208 5.32e-05

Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) superfamily.


Pssm-ID: 411591 [Multi-domain]  Cd Length: 294  Bit Score: 45.28  E-value: 5.32e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022  76 CSLANMSTAF-GLLGSRGLGKAIQESPLIND--------PISAVVVGMLATVVLQSATTTTNILVTMVAANMITVHDAIP 146
Cdd:NF037997  125 MSLFGLGAIFtAMRGFESLAGPLTSLPFVHSllestnesLLLALLIGTVLTAIIQSSSATTGITMSFLNEGILTLPAGIA 204
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1767287022 147 VMIGSELGSSLVNAMVSLAySGKpeQFRRAFSAAIlgdVFNVCGLFVIFPM-EMFTGLIEKVS 208
Cdd:NF037997  205 IMLGANIGTCITALLASIG-SGK--EAKLTAYAHI---WLNVLGVLLFLPFiHLLGEFVALLA 261
 
Name Accession Description Interval E-value
2a58 TIGR01013
Phosphate:Na+ Symporter (PNaS) Family; [Transport and binding proteins, Cations and iron ...
74-533 9.12e-146

Phosphate:Na+ Symporter (PNaS) Family; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 162157 [Multi-domain]  Cd Length: 456  Bit Score: 428.90  E-value: 9.12e-146
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022  74 YVCSLANMSTAFGLLGSRGLGKAIQESPLINDPISAVVVGMLATVVLQSATTTTNILVTMVAANMITVHDAIPVMIGSEL 153
Cdd:TIGR01013   7 FVCSLAVLSAAFILLGAKVGGAIFADILITDNPWASPLLGFLGTVLLQSSSTSRSIVVGMVSAGLLLVLLAIPLIMGANI 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022 154 GSSLVNAMVSLAYSGKPEQFRRAFSAAILGDVFNVCGLFVIFPMEMFTGLIEKVSWWIVDPLISEQG-LSFKTLELLTDP 232
Cdd:TIGR01013  87 GSSVTNAIVAIMQSGDRAWFRRAFIGATVADIFNSSLALVLLPLELTTGGIESVTLLVVLVFGANGGgDAPDLLNSLTAP 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022 233 INQVILQvneveLLNATIRPEMFEANHSFVQRCSFTNG----TRIYNCPYNHLFShtslsdkNIGWIVLFVSIFCLVMCL 308
Cdd:TIGR01013 167 ATALIVQ-----LDNLIIRLIGSLLILPLIDILASTLSslpvPESNLPIEAHIFV-------NVGLILLALPFVRLCARL 234
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022 309 VGIVYLIQKLLDGHAANYVRNLLSKQCPGMWKPCTGYLVMLVGLVVTILIQSNSIFSSSLTPLVGSGVVTLEQMYPLVLG 388
Cdd:TIGR01013 235 ILVVIPLNSLLDGQVAPVILDVINLDTPVPFLWVTGYEALLVGDAMTFIIQSSSVFTSALTPLVGKGVISLERAYPLVLG 314
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022 389 SNIGTTFSGVLAAFSTDPSRFEKALHMAMCQVIYNIIGTCLFYIVPCTRKfPVYLSVKLGVITDHYRWFIVVFISTVFLI 468
Cdd:TIGR01013 315 SNIGTTLTAVLAALLSEDEKRRSALQIAYCHNLFNISGIVLFYPLPCTRK-PIAAARGFGDDGSKYRWFLIVYLVLNFLL 393
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1767287022 469 IPFTIIGLTLLPDNVIVIVFIIILIIAITCCFICVLQNSCKEflPKILHNWSFLPIWMRSLQYYD 533
Cdd:TIGR01013 394 APSLLFGLDLNLARRLVGVKIPFRILELFSSLLHVLQLRCPR--PQSLQTWSFLPDWLRSLKRLD 456
NptA COG1283
Na+/phosphate symporter [Inorganic ion transport and metabolism];
106-472 2.85e-17

Na+/phosphate symporter [Inorganic ion transport and metabolism];


Pssm-ID: 440894 [Multi-domain]  Cd Length: 540  Bit Score: 84.85  E-value: 2.85e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022 106 PISAVVVGMLATVVLQSATTTTNILVTMVAANMITVHDAIPVMIGSELGSSLVNAMVSLAYSgkpeqfrrAFSAAILGdv 185
Cdd:COG1283    47 RLKGVLAGALVTALLQSSSATTVMVVGFVNAGLMTLAQALGVILGANIGTTLTAQLIAFDLS--------ALAPPLIA-- 116
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022 186 fnvCGLFVIFpmemftgliekvswwivdpliseqglsfktlelltdpinqvilqvnevellnatirpemfeanhsfvqrc 265
Cdd:COG1283   117 ---IGVILFL---------------------------------------------------------------------- 123
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022 266 sFTNGTRIyncpynhlfshtslsdKNIGWIVLFvsiFCLVmcLVGIVYLIQKLLDGHAANYVRNLLSKQCPGMWkpctgy 345
Cdd:COG1283   124 -FGKRRRL----------------RQIGRILIG---FGLL--FLGLDLMSEAMEPLRDSPAFRALLASLSGNPL------ 175
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022 346 LVMLVGLVVTILIQSNS----IFSSsltpLVGSGVVTLEQMYPLVLGSNIGTTFSGVLAAFSTDPSrfekALHMAMCQVI 421
Cdd:COG1283   176 LGVLVGALLTALVQSSSatvgLLLA----LAAQGLIPLEAALALVLGANIGTTITALLASIGANVA----ARRAALAHLL 247
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1767287022 422 YNIIGTCLFYIVpctrkFPVYLSVkLGVITDHYRWFIVVF-----ISTVFLIIPFT 472
Cdd:COG1283   248 FNLIGVLIFLPL-----LPPFAAL-VAWLSPDPARQIANFhtlfnLLNALLFLPFI 297
Na_Pi_cotrans pfam02690
Na+/Pi-cotransporter; This is a family of mainly mammalian type II renal Na+/Pi-cotransporters ...
81-164 7.84e-12

Na+/Pi-cotransporter; This is a family of mainly mammalian type II renal Na+/Pi-cotransporters with other related sequences from lower eukaryotes and bacteria some of which are also Na+/Pi-cotransporters. In the kidney the type II renal Na+/Pi-cotransporters protein allows re-absorption of filtered Pi in the proximal tubule.


Pssm-ID: 460653 [Multi-domain]  Cd Length: 137  Bit Score: 62.80  E-value: 7.84e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022  81 MSTAFGLLGSRGLGKAIQEspLINDPISAVVVGMLATVVLQSATTTTNILVTMVAANMITVHDAIPVMIGSELGSSLVNA 160
Cdd:pfam02690   9 MSDGLQKLAGGRLRRILEK--LTSNPLKGFLVGLLVTALLQSSSATTVMVVGFVNAGLLTLAQALGVIMGANIGTTVTAQ 86

                  ....
gi 1767287022 161 MVSL 164
Cdd:pfam02690  87 LIAF 90
Na_Pi_cotrans pfam02690
Na+/Pi-cotransporter; This is a family of mainly mammalian type II renal Na+/Pi-cotransporters ...
348-405 8.70e-11

Na+/Pi-cotransporter; This is a family of mainly mammalian type II renal Na+/Pi-cotransporters with other related sequences from lower eukaryotes and bacteria some of which are also Na+/Pi-cotransporters. In the kidney the type II renal Na+/Pi-cotransporters protein allows re-absorption of filtered Pi in the proximal tubule.


Pssm-ID: 460653 [Multi-domain]  Cd Length: 137  Bit Score: 60.11  E-value: 8.70e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1767287022 348 MLVGLVVTILIQSNSIFSSSLTPLVGSGVVTLEQMYPLVLGSNIGTTFSGVLAAFSTD 405
Cdd:pfam02690  36 FLVGLLVTALLQSSSATTVMVVGFVNAGLLTLAQALGVIMGANIGTTVTAQLIAFDIS 93
NptA COG1283
Na+/phosphate symporter [Inorganic ion transport and metabolism];
77-214 2.69e-10

Na+/phosphate symporter [Inorganic ion transport and metabolism];


Pssm-ID: 440894 [Multi-domain]  Cd Length: 540  Bit Score: 62.89  E-value: 2.69e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022  77 SLANMSTAF-GLLGSRGLGKAIQEspLINDPISAVVVGMLATVVLQSATTTTNILVTMVAANMITVHDAIPVMIGSELGS 155
Cdd:COG1283   146 GLDLMSEAMePLRDSPAFRALLAS--LSGNPLLGVLVGALLTALVQSSSATVGLLLALAAQGLIPLEAALALVLGANIGT 223
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1767287022 156 SlVNAMvsLAYSGKPEQFRRAFSAAILgdvFNVCGLFVIFPmeMFTGLIEKVSWWIVDP 214
Cdd:COG1283   224 T-ITAL--LASIGANVAARRAALAHLL---FNLIGVLIFLP--LLPPFAALVAWLSPDP 274
Na_Pi_symport NF037997
Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) ...
345-472 1.68e-07

Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) superfamily.


Pssm-ID: 411591 [Multi-domain]  Cd Length: 294  Bit Score: 52.99  E-value: 1.68e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022 345 YLVMLVGLVVTILIQSNSIFSSSLTPLVGSGVVTLEQMYPLVLGSNIGTTFSGVLAAFSTDpsrfEKALHMAMCQVIYNI 424
Cdd:NF037997  165 LLALLIGTVLTAIIQSSSATTGITMSFLNEGILTLPAGIAIMLGANIGTCITALLASIGSG----KEAKLTAYAHIWLNV 240
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1767287022 425 IGTCLFY--IVPCTRkFPVYLSVKLGVITDHyrwFIVVF-ISTVFLIIPFT 472
Cdd:NF037997  241 LGVLLFLpfIHLLGE-FVALLASSPDVQLAH---ASVLFnVISSLLVLPFA 287
Na_Pi_symport NF037997
Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) ...
348-430 4.20e-06

Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) superfamily.


Pssm-ID: 411591 [Multi-domain]  Cd Length: 294  Bit Score: 48.75  E-value: 4.20e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022 348 MLVGLVVTILIQSNSIFSSSLTPLVGSGVVTLEQMYPLVLGSNIGTTFSGVLAAFSTD----PSRFEKALHMAMCQVIYN 423
Cdd:NF037997   42 FLTGTVITAILQSSSAVMVLTVGLVSAGILTFRQSIGIILGTNIGTTFTTEFITFDIDrliiPLLIIGALLLFLPRPALK 121

                  ....*..
gi 1767287022 424 IIGTCLF 430
Cdd:NF037997  122 SLGMSLF 128
Na_Pi_symport NF037997
Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) ...
76-208 5.32e-05

Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) superfamily.


Pssm-ID: 411591 [Multi-domain]  Cd Length: 294  Bit Score: 45.28  E-value: 5.32e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022  76 CSLANMSTAF-GLLGSRGLGKAIQESPLIND--------PISAVVVGMLATVVLQSATTTTNILVTMVAANMITVHDAIP 146
Cdd:NF037997  125 MSLFGLGAIFtAMRGFESLAGPLTSLPFVHSllestnesLLLALLIGTVLTAIIQSSSATTGITMSFLNEGILTLPAGIA 204
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1767287022 147 VMIGSELGSSLVNAMVSLAySGKpeQFRRAFSAAIlgdVFNVCGLFVIFPM-EMFTGLIEKVS 208
Cdd:NF037997  205 IMLGANIGTCITALLASIG-SGK--EAKLTAYAHI---WLNVLGVLLFLPFiHLLGEFVALLA 261
NaPi_cotrn_rel TIGR00704
Na/Pi-cotransporter; This model describes essentially the full length of an uncharacterized ...
346-405 6.37e-04

Na/Pi-cotransporter; This model describes essentially the full length of an uncharacterized protein from Bacillus subtilis and correponding lengths of longer proteins from E. coli and Treponema pallidum. PSI-BLAST analysis converges to demonstrate homology to one other group of proteins, type II sodium/phosphate (Na/Pi) cotransporters. A well-conserved repeated domain in this family, approximately 60 residues in length, is also repeated in the Na/Pi cotransporters, although with greater spacing between the repeats. The two families share additional homology in the region after the first repeat, share the properly of having extensive hydrophobic regions, and may be similar in function. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273225 [Multi-domain]  Cd Length: 308  Bit Score: 42.21  E-value: 6.37e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022 346 LVMLVGLVVTILIQSNSIFSSSLTPLVGSGVVTLEQMYPLVLGSNIGTTFSGVLAAFSTD 405
Cdd:TIGR00704  46 KAFCAGIGFTAILQSSNAFMMIVIGFVAADLLAFAPAIPIILGADVGSAFMAEFIAFDLD 105
NaPi_cotrn_rel TIGR00704
Na/Pi-cotransporter; This model describes essentially the full length of an uncharacterized ...
298-429 1.12e-03

Na/Pi-cotransporter; This model describes essentially the full length of an uncharacterized protein from Bacillus subtilis and correponding lengths of longer proteins from E. coli and Treponema pallidum. PSI-BLAST analysis converges to demonstrate homology to one other group of proteins, type II sodium/phosphate (Na/Pi) cotransporters. A well-conserved repeated domain in this family, approximately 60 residues in length, is also repeated in the Na/Pi cotransporters, although with greater spacing between the repeats. The two families share additional homology in the region after the first repeat, share the properly of having extensive hydrophobic regions, and may be similar in function. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273225 [Multi-domain]  Cd Length: 308  Bit Score: 41.44  E-value: 1.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767287022 298 FVSIFCLVMCLVGIVYLIQKLLDghaANYVRNLLSKQCPGMWkpctgyLVMLVGLVVTILIQSNSIFSSSLTPLVGSGVV 377
Cdd:TIGR00704 134 FIGLGIIFFAIEGFSHAAGPITK---AKGGADIFAHLNDDIL------LAALIGAMFAAIIHSSLAAIGILASFMAAGII 204
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1767287022 378 TLEQMYPLVLGSNIGTTFSGVLAAFSTDPSrfekALHMAMCQVIYNIIGTCL 429
Cdd:TIGR00704 205 GFPQALCLVIGANIGSCILAMLAASAAGAA----AKQTALAHLLFKLLGSAI 252
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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