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    dex-1 Dendrite extension defective protein 1 [ Caenorhabditis elegans ]

    Gene ID: 175761, updated on 4-Jan-2025

    Summary

    Official Symbol
    dex-1
    Official Full Name
    Dendrite extension defective protein 1
    Primary source
    WormBase:WBGene00017028
    Locus tag
    CELE_D1044.2
    See related
    AllianceGenome:WB:WBGene00017028
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable calcium ion binding activity. Involved in amphid sensory organ dendrite retrograde extension. Located in dendrite membrane. Is expressed in anterior deirid sensillum; epithelial cell; excretory system; pharynx; and rectum. [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

    See dex-1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    15
    Sequence:
    Chromosome: III; NC_003281.10 (5526104..5535507)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein Neighboring gene putative kinase-like protein D1044.1

    General gene information

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables calcium ion binding  
    enables molecular_function  
    Component Evidence Code Pubs
    located_in cell projection  
    located_in dendrite  
    located_in dendrite membrane PubMed 
    located_in extracellular region  
    is_active_in extracellular space  
    located_in membrane  

    General protein information

    Preferred Names
    Dendrite extension defective protein 1
    NP_001379843.1
    • Confirmed by transcript evidence
    NP_498181.3
    • Partially confirmed by transcript evidence
    NP_498182.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      5526104..5535507
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_065781.6 → NP_498182.2  Dendrite extension defective protein 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498182.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D7SFI8, P41950, Q8TA75, Q95QP5, Q95QP6
      Conserved Domains (2) summary
      smart00539
      Location:163 → 304
      NIDO; Extracellular domain of unknown function in nidogen (entactin) and hypothetical proteins
      pfam12947
      Location:413 → 445
      EGF_3; EGF domain
    2. NM_001392098.1 → NP_001379843.1  Dendrite extension defective protein 1 [Caenorhabditis elegans]

      Status: REVIEWED

      Conserved Domains (2) summary
      smart00539
      Location:146 → 287
      NIDO; Extracellular domain of unknown function in nidogen (entactin) and hypothetical proteins
      pfam12947
      Location:396 → 428
      EGF_3; EGF domain
    3. NM_065780.6 → NP_498181.3  Dendrite extension defective protein 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498181.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P41950
      Conserved Domains (2) summary
      smart00539
      Location:146 → 287
      NIDO; Extracellular domain of unknown function in nidogen (entactin) and hypothetical proteins
      pfam12947
      Location:396 → 428
      EGF_3; EGF domain
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