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    Slco6d1 solute carrier organic anion transporter family, member 6d1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 367321, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Slco6d1provided by RGD
    Official Full Name
    solute carrier organic anion transporter family, member 6d1provided by RGD
    Primary source
    RGD:1359388
    See related
    EnsemblRapid:ENSRNOG00000031146 AllianceGenome:RGD:1359388
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable sodium-independent organic anion transmembrane transporter activity. Predicted to be involved in sodium-independent organic anion transport. Predicted to be active in basolateral plasma membrane. Orthologous to human SLCO6A1 (solute carrier organic anion transporter family member 6A1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 284.0) See more
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    Genomic context

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    See Slco6d1 in Genome Data Viewer
    Location:
    9q36
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (105030437..105187274, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (97583093..97739994, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (104709911..104870399, complement)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene solute carrier organic anion transporter family member 6c1 like, pseudogene 1 Neighboring gene uncharacterized LOC134480421 Neighboring gene solute carrier organic anion transporter family, member 6c1 Neighboring gene tumor protein, translationally-controlled 1 pseudogene 6 Neighboring gene potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2-like Neighboring gene peptidylglycine alpha-amidating monooxygenase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables sodium-independent organic anion transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in sodium-independent organic anion transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in basolateral plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    solute carrier organic anion transporter family, member 6d1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001410265.1 → NP_001397194.1  solute carrier organic anion transporter family, member 6d1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      A0A0G2JWY3, A0A9K3Y706, F1LNX6, Q5XI61
      Related
      ENSRNOP00000070061.1, ENSRNOT00000084398.3

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      105030437..105187274 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017596585.3 → XP_017452074.1  solute carrier organic anion transporter family, member 6d1 isoform X1

      UniProtKB/TrEMBL
      A0A9K3Y706, F1LNX6, Q5XI61

    2. XM_063267542.1 → XP_063123612.1  solute carrier organic anion transporter family, member 6d1 isoform X5

      UniProtKB/TrEMBL
      A0A9K3Y706, F1LNX6, Q5XI61

    3. XM_063267541.1 → XP_063123611.1  solute carrier organic anion transporter family, member 6d1 isoform X4

      UniProtKB/TrEMBL
      A0A9K3Y706, F1LNX6, Q5XI61

    4. XM_039084005.2 → XP_038939933.1  solute carrier organic anion transporter family, member 6d1 isoform X3

      UniProtKB/TrEMBL
      A0A9K3Y706, F1LNX6, Q5XI61
      Conserved Domains (1) summary
      cl28910
      Location:84 → 547
      MFS; Major Facilitator Superfamily

    5. XM_006245580.5 → XP_006245642.1  solute carrier organic anion transporter family, member 6d1 isoform X2

      UniProtKB/TrEMBL
      A0A9K3Y706, F1LNX6, Q5XI61
      Related
      ENSRNOP00000060190.2, ENSRNOT00000065171.4
      Conserved Domains (3) summary
      cd06174
      Location:88 → 465
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      cd01330
      Location:478 → 531
      KAZAL_SLC21; The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a ...
      pfam03137
      Location:86 → 645
      OATP; Organic Anion Transporter Polypeptide (OATP) family

    6. XM_017596584.3 → XP_017452073.1  solute carrier organic anion transporter family, member 6d1 isoform X1

      UniProtKB/TrEMBL
      A0A9K3Y706, F1LNX6, Q5XI61

    7. XM_039084007.2 → XP_038939935.1  solute carrier organic anion transporter family, member 6d1 isoform X6

      UniProtKB/TrEMBL
      A0A9K3Y706, F1LNX6, Q5XI61
      Conserved Domains (1) summary
      cl28910
      Location:123 → 498
      MFS; Major Facilitator Superfamily

    8. XM_063267543.1 → XP_063123613.1  solute carrier organic anion transporter family, member 6d1 isoform X7

      UniProtKB/TrEMBL
      A0A9K3Y706, F1LNX6, Q5XI61

    9. XM_039084008.1 → XP_038939936.1  solute carrier organic anion transporter family, member 6d1 isoform X8

      Conserved Domains (1) summary
      cl28910
      Location:1 → 361
      MFS; Major Facilitator Superfamily

    10. XM_039084012.2 → XP_038939940.1  solute carrier organic anion transporter family, member 6d1 isoform X11

      Conserved Domains (1) summary
      cl28910
      Location:84 → 410
      MFS; Major Facilitator Superfamily

    11. XM_063267545.1 → XP_063123615.1  solute carrier organic anion transporter family, member 6d1 isoform X13

    12. XM_039084010.2 → XP_038939938.1  solute carrier organic anion transporter family, member 6d1 isoform X9

      Conserved Domains (1) summary
      cl28910
      Location:84 → 410
      MFS; Major Facilitator Superfamily

    13. XM_039084011.2 → XP_038939939.1  solute carrier organic anion transporter family, member 6d1 isoform X10

      Conserved Domains (1) summary
      cl28910
      Location:84 → 410
      MFS; Major Facilitator Superfamily

    14. XM_039084013.2 → XP_038939941.1  solute carrier organic anion transporter family, member 6d1 isoform X12

      Conserved Domains (1) summary
      cl28910
      Location:84 → 321
      MFS; Major Facilitator Superfamily

    RNA

    1. XR_005488950.2 RNA Sequence

    2. XR_010054621.1 RNA Sequence

    3. XR_005488948.2 RNA Sequence

    4. XR_005488949.2 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001014270.1: Suppressed sequence

      Description
      NM_001014270.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

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