Scgb3a2 secretoglobin, family 3A, member 2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Scgb3a2provided by RGD
Official Full Name: secretoglobin, family 3A, member 2provided by RGD
Primary source: RGD:1564790
See related: EnsemblRapid:ENSRNOG00000026912 AllianceGenome:RGD:1564790
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Pnsp1
Summary: Predicted to be located in extracellular region. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in allergic rhinitis and asthma. Orthologous to human SCGB3A2 (secretoglobin family 3A member 2). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Restricted expression toward (RPKM 1632.9) See more
Orthologs: human mouse all
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Genomic context

Location:: 18q11

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	18	NC_086036.1 (36183745..36186667)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	18	NC_051353.1 (35932840..35935762)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	18	NC_005117.4 (38292822..38295744)

Chromosome 18 - NC_086036.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
located_in extracellular region	ISO Inferred from Sequence Orthology more info
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: secretoglobin family 3A member 2

Names: pneumo secretory protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001024283.1 → NP_001019454.1 secretoglobin family 3A member 2

See identical proteins and their annotated locations for NP_001019454.1

Status: PROVISIONAL

Source sequence(s)

AF439547

UniProtKB/TrEMBL

Q71MM7

Related

ENSRNOP00000105178.1, ENSRNOT00000126151.1

Conserved Domains (1) summary

cl11457
Location:1 → 91

Secretoglobin; Secretoglobins are relatively small, secreted, disulphide-bridged dimeric proteins with encoding genes sharing substantial sequence similarity. Their family subunits may be grouped into five subfamilies, A-E. Uteroglobin (subfamily A), which is identical ...