NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|66730537|ref|NP_001019454|]
View 

secretoglobin family 3A member 2 [Rattus norvegicus]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
SCGB3A pfam20490
Secretoglobin 3A; This family includes secretoglobin family 3A member 1 (SCGB3A1) and member 2 ...
 20-87 6.29e-34

Secretoglobin 3A; This family includes secretoglobin family 3A member 1 (SCGB3A1) and member 2 (SCGB3A2), also known as uteroglobin-related proteins. They are a small secreted proteins expressed in airway epithelial cells. SCGB3A2, also known as UGRP1, has an important anti-inflammatory activity and is involved in asthma. SCGB3A2 mediates its anti-inflammatory action through inhibition of ERK and JNK activation. It is also involved in lung development and has anti-fibrotic activity in lung.


:

Pssm-ID: 466639  Cd Length: 68  Bit Score: 111.17  E-value: 6.29e-34
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 66730537   20 TAFLINSVPLPVDKVLPLPLDNLIPLFDPLKMLLKTLGISVEHLVEGLKKCVNELGPEASEAVKKLLE 87
Cdd:pfam20490  1 AAFFVNSVAKPVAALAPLPLDSILPFFNPLKLLLTSLGIPVEHLVEGSRKCVAELGPEAVEAVKKLLG 68
 
Name Accession Description Interval E-value
SCGB3A pfam20490
Secretoglobin 3A; This family includes secretoglobin family 3A member 1 (SCGB3A1) and member 2 ...
 20-87 6.29e-34

Secretoglobin 3A; This family includes secretoglobin family 3A member 1 (SCGB3A1) and member 2 (SCGB3A2), also known as uteroglobin-related proteins. They are a small secreted proteins expressed in airway epithelial cells. SCGB3A2, also known as UGRP1, has an important anti-inflammatory activity and is involved in asthma. SCGB3A2 mediates its anti-inflammatory action through inhibition of ERK and JNK activation. It is also involved in lung development and has anti-fibrotic activity in lung.


Pssm-ID: 466639  Cd Length: 68  Bit Score: 111.17  E-value: 6.29e-34
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 66730537   20 TAFLINSVPLPVDKVLPLPLDNLIPLFDPLKMLLKTLGISVEHLVEGLKKCVNELGPEASEAVKKLLE 87
Cdd:pfam20490  1 AAFFVNSVAKPVAALAPLPLDSILPFFNPLKLLLTSLGIPVEHLVEGSRKCVAELGPEAVEAVKKLLG 68
 
Name Accession Description Interval E-value
SCGB3A pfam20490
Secretoglobin 3A; This family includes secretoglobin family 3A member 1 (SCGB3A1) and member 2 ...
 20-87 6.29e-34

Secretoglobin 3A; This family includes secretoglobin family 3A member 1 (SCGB3A1) and member 2 (SCGB3A2), also known as uteroglobin-related proteins. They are a small secreted proteins expressed in airway epithelial cells. SCGB3A2, also known as UGRP1, has an important anti-inflammatory activity and is involved in asthma. SCGB3A2 mediates its anti-inflammatory action through inhibition of ERK and JNK activation. It is also involved in lung development and has anti-fibrotic activity in lung.


Pssm-ID: 466639  Cd Length: 68  Bit Score: 111.17  E-value: 6.29e-34
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 66730537   20 TAFLINSVPLPVDKVLPLPLDNLIPLFDPLKMLLKTLGISVEHLVEGLKKCVNELGPEASEAVKKLLE 87
Cdd:pfam20490  1 AAFFVNSVAKPVAALAPLPLDSILPFFNPLKLLLTSLGIPVEHLVEGSRKCVAELGPEAVEAVKKLLG 68
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH