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    DIS3L DIS3 like exosome 3'-5' exoribonuclease [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 710238, updated on 17-Aug-2024

    Summary

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    Official Symbol
    DIS3Lprovided by VGNC
    Official Full Name
    DIS3 like exosome 3'-5' exoribonucleaseprovided by VGNC
    Primary source
    VGNC:VGNC:71796
    See related
    Ensembl:ENSMMUG00000003693
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See DIS3L in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (42881515..42941287)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (43022896..43086314)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene RAB11A, member RAS oncogene family Neighboring gene multiple EGF like domains 11 Neighboring gene 60S ribosomal protein L7a pseudogene Neighboring gene small Cajal body-specific RNA 14 Neighboring gene TIMELESS interacting protein Neighboring gene mitogen-activated protein kinase kinase 1 Neighboring gene small nuclear RNA activating complex polypeptide 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 3'-5'-RNA exonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in rRNA catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of cytoplasmic exosome (RNase complex) IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DIS3-like exonuclease 1
    Names
    DIS3 mitotic control homolog-like
    XP_014997968.2
    XP_028706231.1
    XP_028706232.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001194471.3 → NP_001181400.2  DIS3-like exonuclease 1

      Status: VALIDATED

      Source sequence(s)
      QNVO02000411
      UniProtKB/TrEMBL
      A0A5F8ATK4, F6SH23, H9EV62
      Conserved Domains (2) summary
      COG0557
      Location:265 → 974
      VacB; Exoribonuclease R [Transcription]
      cd09862
      Location:11 → 188
      PIN_Rrp44-like; VapC-like PIN domain of yeast exosome subunit Rrp44 endoribonuclease and other eukaryotic homologs

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      42881515..42941287
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028850398.1 → XP_028706231.1  DIS3-like exonuclease 1 isoform X2

      UniProtKB/TrEMBL
      A0A5K1VUD2, F6SH23, H9EV62
      Related
      ENSMMUP00000004924.4, ENSMMUT00000005228.4
      Conserved Domains (2) summary
      COG0557
      Location:265 → 943
      VacB; Exoribonuclease R [Transcription]
      cd09862
      Location:11 → 188
      PIN_Rrp44-like; VapC-like PIN domain of yeast exosome subunit Rrp44 endoribonuclease and other eukaryotic homologs

    2. XM_015142482.2 → XP_014997968.2  DIS3-like exonuclease 1 isoform X1

      Related
      ENSMMUP00000080241.1, ENSMMUT00000083357.1
      Conserved Domains (2) summary
      COG0557
      Location:265 → 974
      VacB; Exoribonuclease R [Transcription]
      cd09862
      Location:11 → 188
      PIN_Rrp44-like; VapC-like PIN domain of yeast exosome subunit Rrp44 endoribonuclease and other eukaryotic homologs

    3. XM_028850399.1 → XP_028706232.1  DIS3-like exonuclease 1 isoform X3

      Conserved Domains (1) summary
      COG0557
      Location:19 → 604
      VacB; Exoribonuclease R [Transcription]
    Nucleotide Protein
    Heading Accession and Version

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