View
Concise Results
Standard Results
Full Results
DIS3-like exonuclease 1 isoform X3 [Macaca mulatta]
Protein Classification
ribonuclease R family protein ( domain architecture ID 11426128 )
ribonuclease R (RNaseR or RNR) family protein similar to RNR, a 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
List of domain hits
Name
Accession
Description
Interval
E-value
VacB super family
cl43181 Exoribonuclease R [Transcription];
22-546
6.29e-107
Exoribonuclease R [Transcription];
COG0557 :Pssm-ID: 440323 [Multi-domain]
Cd Length: 711
Bit Score: 340.16
E-value: 6.29e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 22 VVV R I DSWESTSVY P N G HF V R VLG RI GD LEG EI ATILVENSISVI p F S ----- EA Q mcempv NT P E npw K V SREEEQK R K 96
Cdd:COG0557 177 VVV E I TRYPERRGP P E G RV V E VLG SP GD PGA EI LIAIRKHGLPHE - F P eevla EA E ------ AL P D --- E V PEADLKG R R 246
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 97 DLR KSH LV f S ID PKGCE D V DD TL S IRT L N NG NLE LGVHIADV T H F V A P N S YI D I EAR T R A T TY YL A DR RYD MLP SV LS AD 176
Cdd:COG0557 247 DLR DLP LV - T ID GEDAK D F DD AV S AEK L D NG GWR LGVHIADV S H Y V R P G S AL D R EAR K R G T SV YL P DR VIP MLP ER LS NG 325
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 177 LCSL LG G V DR Y A V S IMW E L D KTS y E IKEVWYG R TI IRS AYK L F YE AA Q EL LDG N fsvvddipefkdld EKSRQAKLEE LV 256
Cdd:COG0557 326 LCSL NP G E DR L A M S CEM E I D AKG - E VVSYEFY R SV IRS DAR L T YE EV Q AI LDG K -------------- DEELREEYAD LV 390
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 257 WAIGK L TDI A RHV R AK R DGC GA LELEGV E VRVQ LD DKKNIH D LI P KQPLEV H ETVA E C M I LAN HW VA KKI - WESF P hq A L 335
Cdd:COG0557 391 PMLEE L YEL A KIL R KA R EKR GA IDFDLP E TKII LD EEGKPE D IV P RERNDA H KLIE E F M L LAN EA VA EFL e KLKL P -- F L 468
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 336 L R Q H PP P HQ E FFSE LRE CAKAK G FFI --- D TRSN K T L ADS L DNAND - P HDPIV N R - LLRSM A t QA M snal Y fstgsc AE E 410
Cdd:COG0557 469 Y R V H EE P DP E KLEA LRE FLANL G LKL kgg D EPTP K D L QKL L EQVKG r P EEELL N T l LLRSM K - QA V ---- Y ------ SP E 537
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 411 EFH H Y GLAL DK YTHFTSPIRRY S D IV VHR L L M A AISKDKKMEIKGN L ft NKD LEE LCR H INNRN R A A QHSQKQSTE L FQC 490
Cdd:COG0557 538 NIG H F GLAL EA YTHFTSPIRRY P D LL VHR A L K A YLEGKRSPGLQEY L -- EEE LEE IAE H CSETE R R A DEAERDVVD L KKA 615
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*..
gi 1622950836 491 M Y F KD K dpa TE E rc ISD GVI YSIRTN G VL V FIPRF G I kgaaylknk D GLV - I SS GP D 546
Cdd:COG0557 616 E Y M KD R --- VG E -- EFE GVI SGVTSF G LF V ELDEL G V --------- E GLV h V SS LG D 658
Rrp44_S1 super family
cl25439 S1 domain; This domain corresponds to the S1 domain found at the C-terminus of ribonucleases ...
511-588
4.23e-08
S1 domain; This domain corresponds to the S1 domain found at the C-terminus of ribonucleases such as yeast Rrp44.
pfam17215 :Pssm-ID: 435792
Cd Length: 87
Bit Score: 50.99
E-value: 4.23e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 511 Y S I RT -- NG VL VF I P R FGI K G AAY L KNKD G LVISSGP D S rsawkpgsl QRFQNKITSTTT d G ESV T FHL FD H V T VR ISVQ 588
Cdd:pfam17215 6 Y V I KV fn NG IV VF V P K FGI E G LIR L EDLT G DEPEAEF D A --------- DEYSLTFPDKGS - G KKR T VGV FD K V R VR VKSV 75
Name
Accession
Description
Interval
E-value
VacB
COG0557 Exoribonuclease R [Transcription];
22-546
6.29e-107
Exoribonuclease R [Transcription];
Pssm-ID: 440323 [Multi-domain]
Cd Length: 711
Bit Score: 340.16
E-value: 6.29e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 22 VVV R I DSWESTSVY P N G HF V R VLG RI GD LEG EI ATILVENSISVI p F S ----- EA Q mcempv NT P E npw K V SREEEQK R K 96
Cdd:COG0557 177 VVV E I TRYPERRGP P E G RV V E VLG SP GD PGA EI LIAIRKHGLPHE - F P eevla EA E ------ AL P D --- E V PEADLKG R R 246
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 97 DLR KSH LV f S ID PKGCE D V DD TL S IRT L N NG NLE LGVHIADV T H F V A P N S YI D I EAR T R A T TY YL A DR RYD MLP SV LS AD 176
Cdd:COG0557 247 DLR DLP LV - T ID GEDAK D F DD AV S AEK L D NG GWR LGVHIADV S H Y V R P G S AL D R EAR K R G T SV YL P DR VIP MLP ER LS NG 325
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 177 LCSL LG G V DR Y A V S IMW E L D KTS y E IKEVWYG R TI IRS AYK L F YE AA Q EL LDG N fsvvddipefkdld EKSRQAKLEE LV 256
Cdd:COG0557 326 LCSL NP G E DR L A M S CEM E I D AKG - E VVSYEFY R SV IRS DAR L T YE EV Q AI LDG K -------------- DEELREEYAD LV 390
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 257 WAIGK L TDI A RHV R AK R DGC GA LELEGV E VRVQ LD DKKNIH D LI P KQPLEV H ETVA E C M I LAN HW VA KKI - WESF P hq A L 335
Cdd:COG0557 391 PMLEE L YEL A KIL R KA R EKR GA IDFDLP E TKII LD EEGKPE D IV P RERNDA H KLIE E F M L LAN EA VA EFL e KLKL P -- F L 468
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 336 L R Q H PP P HQ E FFSE LRE CAKAK G FFI --- D TRSN K T L ADS L DNAND - P HDPIV N R - LLRSM A t QA M snal Y fstgsc AE E 410
Cdd:COG0557 469 Y R V H EE P DP E KLEA LRE FLANL G LKL kgg D EPTP K D L QKL L EQVKG r P EEELL N T l LLRSM K - QA V ---- Y ------ SP E 537
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 411 EFH H Y GLAL DK YTHFTSPIRRY S D IV VHR L L M A AISKDKKMEIKGN L ft NKD LEE LCR H INNRN R A A QHSQKQSTE L FQC 490
Cdd:COG0557 538 NIG H F GLAL EA YTHFTSPIRRY P D LL VHR A L K A YLEGKRSPGLQEY L -- EEE LEE IAE H CSETE R R A DEAERDVVD L KKA 615
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*..
gi 1622950836 491 M Y F KD K dpa TE E rc ISD GVI YSIRTN G VL V FIPRF G I kgaaylknk D GLV - I SS GP D 546
Cdd:COG0557 616 E Y M KD R --- VG E -- EFE GVI SGVTSF G LF V ELDEL G V --------- E GLV h V SS LG D 658
RNB
pfam00773 RNB domain; This domain is the catalytic domain of ribonuclease II.
95-445
3.97e-105
RNB domain; This domain is the catalytic domain of ribonuclease II.
Pssm-ID: 459934 [Multi-domain]
Cd Length: 314
Bit Score: 322.31
E-value: 3.97e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 95 RKDLR KS h LVFS IDP KGCE D V DD TL S IRT L N NG NLE LGVHIADV T H F V A P N S YI D I EAR T R A T TY YL A DR RYD MLP SV LS 174
Cdd:pfam00773 1 RKDLR DL - PFIT IDP ADAK D L DD AI S VEK L P NG GYR LGVHIADV S H Y V P P G S PL D R EAR K R G T SV YL P DR VIP MLP EK LS 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 175 A DLCSL LG G V DR Y A V S IMWEL D KT s Y E IKEVWYGRTI IRS AYK L F YE AAQE LL D G NFSVV D DIPEFK DL DE ksrqaklee 254
Cdd:pfam00773 80 N DLCSL NP G E DR L A L S VEITI D AD - G E VTSYEIYPSV IRS KAR L T YE EVDD LL E G KDAEK D KPDLAE DL RL --------- 149
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 255 lvwaigk L TDI A RHV RAKR DGC GAL E L EGV E VRVQ LD DKKN I h D LIPKQPLEV H ETVA E C M I LAN HW VA KKI w ESFPHQ A 334
Cdd:pfam00773 150 ------- L YEL A KIL RAKR LQR GAL D L DTP E NKLI LD EEGV I - D ILIQERTDA H SLIE E F M L LAN EA VA RHL - QELGIP A 220
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 335 L L R Q HP P P HQ E FFSE L RECAKAK gffidt RSN K T L AD SL DNAN D P hdpiv N RLL RSMATQA M SN A L Y FS tgscae E EFH H 414
Cdd:pfam00773 221 L Y R V HP E P DL E KLNS L IKLLQLL ------ PDD K G L SK SL EKIK D D ----- E RLL SILLLRT M PR A E Y SP ------ E PLG H 283
330 340 350
....*....|....*....|....*....|.
gi 1622950836 415 Y GL A LD K YTHFTSPIRRY S D IV VHR L L M A AI 445
Cdd:pfam00773 284 F GL G LD I YTHFTSPIRRY P D LI VHR Q L K A LL 314
RNB
smart00955 This domain is the catalytic domain of ribonuclease II;
95-447
3.10e-99
This domain is the catalytic domain of ribonuclease II;
Pssm-ID: 214935 [Multi-domain]
Cd Length: 286
Bit Score: 306.12
E-value: 3.10e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 95 R K DLR k SHLV F S IDP KGCE D V DD TL S IRT L N NG NLE LGVHIADV T H F V A P N S YI D I EAR T R A T TY YL A DR RYD MLP SV LS 174
Cdd:smart00955 1 R V DLR - DLPL F T IDP EDAK D I DD AV S VEK L D NG GYR LGVHIADV S H Y V K P G S AL D R EAR K R G T SV YL P DR VIP MLP EE LS 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 175 AD LCSL LG G V DR Y A V S IMWE LD KTSY EI KEVWYG R TI IRS AYK L F YE AAQEL L D gnfsvvddipefkdldeksrqaklee 254
Cdd:smart00955 80 NG LCSL NP G E DR L A L S VEMT LD ADGG EI LDYEFY R SV IRS KAR L T YE EVDAI L E -------------------------- 133
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 255 lvwaigkltdiarhvrakrdgcgalelegvev RVQ LD DKKN I H D LI P KQPLEV H ET V A E C MILAN HW VA KKIWESFP h QA 334
Cdd:smart00955 134 -------------------------------- KIV LD EEGK I E D IV P RERNDA H SL V E E F MILAN EA VA RFLAKNGI - PG 180
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 335 L L R Q H PP P HQ E FFS E - L R E CAKAK G FFI - DTRSN K T LA DS L DNAN D PHD piv N RLL RSMATQA M SN A L Y FSTG S caeeef 412
Cdd:smart00955 181 L Y R V H EG P DP E KLA E l L K E FLALL G LLL l GGDGP K A LA KL L EKIR D SPE --- E RLL ELLLLRS M PH A E Y SVDN S ------ 251
330 340 350
....*....|....*....|....*....|....*
gi 1622950836 413 H H Y GLALD K YTHFTSPIRRY S D IV VHR L L M AA ISK 447
Cdd:smart00955 252 G H F GLALD A YTHFTSPIRRY P D LI VHR Q L K AA LRG 286
RNase_R
TIGR02063 ribonuclease R; This family consists of an exoribonuclease, ribonuclease R, also called VacB. ...
22-546
5.49e-94
ribonuclease R; This family consists of an exoribonuclease, ribonuclease R, also called VacB. It is one of the eight exoribonucleases reported in E. coli and is broadly distributed throughout the bacteria. In E. coli, double mutants of this protein and polynucleotide phosphorylase are not viable. Scoring between trusted and noise cutoffs to the model are shorter, divergent forms from the Chlamydiae, and divergent forms from the Campylobacterales (including Helicobacter pylori) and Leptospira interrogans. [Transcription, Degradation of RNA]
Pssm-ID: 273947 [Multi-domain]
Cd Length: 709
Bit Score: 306.12
E-value: 5.49e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 22 V V V R I DSWESTSVYPN G HF V RV LG RIG D LEGE I AT I LVENS I s VIP F S E AQMC E mpvn TPEN P WK V SR EE EQK RKDLR KS 101
Cdd:TIGR02063 178 V L V E I TKYPDRNRPAI G KV V EI LG HAD D PGID I LI I IRKHG I - PYE F P E EVLD E ---- AAKI P EE V PE EE IKG RKDLR DL 252
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 102 h LVFS ID PKGCE D V DD TLSIRT L NN GN LE LGV H IADV T H F V APN S YI D I EA RT R A T TY YL A DR RYD MLP SV LS ADL CSL L 181
Cdd:TIGR02063 253 - PFVT ID GEDAK D F DD AVYVEK L KD GN YK LGV A IADV S H Y V REG S AL D K EA LK R G T SV YL P DR VIP MLP ER LS NGI CSL N 331
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 182 GGV DR YAV S IMW E L DK ---- TS YE IK E vwygr TI I R S AYK L F Y EAAQELLD G N fsvvddipef KD LD E K sr QAK L E E LVW 257
Cdd:TIGR02063 332 PNE DR LTL S CEM E I DK kgrv KK YE FY E ----- AV I N S HAR L T Y NQVNDIIE G K ---------- DA LD K K -- EPP L K E MLK 394
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 258 AIGK L TD I A R HV R A KR dgc GA LELEGV E VRVQ LD DKKNIH D LI P KQPLEV H ETVA E C MI L AN HW VA KKI w E SFPHQALL R 337
Cdd:TIGR02063 395 NLFE L YK I L R KK R K KR --- GA IDFDSK E AKII LD ENGKPI D IV P RERGDA H KLIE E F MI A AN ET VA EHL - E KAKLPFIY R 470
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 338 Q H PP P HQ E ---- FFSE L RECA - KA KG FFI D TRSN K TLADS L - DNAND P HDPIV N R - LLRSM A t QA M snaly F S T gscae E 410
Cdd:TIGR02063 471 V H ER P SE E klqn LREF L KTLG i TL KG GTS D KPQP K DFQKL L e KVKGR P EEELI N T v LLRSM Q - QA K ----- Y S P ----- E 539
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 411 EFH H Y GLAL DK YTHFTSPIRRY S D IV VHRL LMA A ISKDKK - MEI K GNLFTNKD LEE LCR H INNRN R A A QHSQKQSTELFQ 489
Cdd:TIGR02063 540 NIG H F GLAL EY YTHFTSPIRRY P D LI VHRL IKK A LFGGEN t TTE K EREYLEAK LEE IAE H SSKTE R R A DEAERDVNDWKK 619
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*...
gi 1622950836 490 CM Y FKD K dpate ERCISD GVI YSIRTN G VL V FIPRFG I kgaaylknk D GLV - IS SGP D 546
Cdd:TIGR02063 620 AE Y MSE K ----- IGEEFE GVI SGVTSF G LF V ELENNT I --------- E GLV h IS TLK D 663
PRK11642
PRK11642 ribonuclease R;
52-449
3.67e-34
ribonuclease R;
Pssm-ID: 236944 [Multi-domain]
Cd Length: 813
Bit Score: 139.49
E-value: 3.67e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 52 G E I ATI L VE N --- SIS V -------- IP FS ----- E A Q MCEMPVNT PE npwkvsr E EEQK R K DLR KSH LV f S ID PKGCE D V 115
Cdd:PRK11642 208 G K I VEV L GD N mgt GMA V dialrthe IP YI wpqav E Q Q VAGLKEEV PE ------- E AKAG R V DLR DLP LV - T ID GEDAR D F 279
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 116 DD TLSIRTLNN G NLE L G V H IADV THF V A P NSYI D I EAR T R A T TY Y LADRRYD MLP S VLS AD LCSL LGG VDR ------ YAV 189
Cdd:PRK11642 280 DD AVYCEKKRG G GWR L W V A IADV SYY V R P PTPL D R EAR N R G T SV Y FPSQVVP MLP E VLS NG LCSL NPQ VDR lcmvce MTI 359
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 190 S IMWE L dk T S Y EIK E vwygr TIIR S AYK L F Y EAAQEL L D G NFSVVDDI - P EF K D L D E ksrqak L EE L V waig K LT D I AR H 268
Cdd:PRK11642 360 S SKGR L -- T G Y KFY E ----- AVMS S HAR L T Y TKVWHI L Q G DQDLREQY a P LV K H L E E ------ L HN L Y ---- K VL D K AR E 422
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 269 V R akrdgc G ALEL E GV E VRVQLDDKKN I HDLIPK Q PLEV H ETVA ECMILAN HWV A KKI w E SFPHQ AL L R Q H PP P HQ E FFS 348
Cdd:PRK11642 423 E R ------ G GISF E SE E AKFIFNAERR I ERIEQT Q RNDA H KLIE ECMILAN ISA A RFV - E KAKEP AL F R I H DK P ST E AIT 495
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 349 EL R ECAKAK G FFI --- DTRSNKTL A DS L DNAN D PH D piv NRL L RS M ATQA M SN A L Y fstgsc AE E EFH H Y GLAL DK Y T HF 425
Cdd:PRK11642 496 SF R SVLAEL G LEL pgg NKPEPRDY A EL L ESVA D RP D --- AEM L QT M LLRS M KQ A I Y ------ DP E NRG H F GLAL QS Y A HF 566
410 420
....*....|....*....|....
gi 1622950836 426 TSPIRRY S D IVV HR LLMAAIS K DK 449
Cdd:PRK11642 567 TSPIRRY P D LSL HR AIKYLLA K EQ 590
Rrp44_S1
pfam17215 S1 domain; This domain corresponds to the S1 domain found at the C-terminus of ribonucleases ...
511-588
4.23e-08
S1 domain; This domain corresponds to the S1 domain found at the C-terminus of ribonucleases such as yeast Rrp44.
Pssm-ID: 435792
Cd Length: 87
Bit Score: 50.99
E-value: 4.23e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 511 Y S I RT -- NG VL VF I P R FGI K G AAY L KNKD G LVISSGP D S rsawkpgsl QRFQNKITSTTT d G ESV T FHL FD H V T VR ISVQ 588
Cdd:pfam17215 6 Y V I KV fn NG IV VF V P K FGI E G LIR L EDLT G DEPEAEF D A --------- DEYSLTFPDKGS - G KKR T VGV FD K V R VR VKSV 75
Name
Accession
Description
Interval
E-value
VacB
COG0557 Exoribonuclease R [Transcription];
22-546
6.29e-107
Exoribonuclease R [Transcription];
Pssm-ID: 440323 [Multi-domain]
Cd Length: 711
Bit Score: 340.16
E-value: 6.29e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 22 VVV R I DSWESTSVY P N G HF V R VLG RI GD LEG EI ATILVENSISVI p F S ----- EA Q mcempv NT P E npw K V SREEEQK R K 96
Cdd:COG0557 177 VVV E I TRYPERRGP P E G RV V E VLG SP GD PGA EI LIAIRKHGLPHE - F P eevla EA E ------ AL P D --- E V PEADLKG R R 246
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 97 DLR KSH LV f S ID PKGCE D V DD TL S IRT L N NG NLE LGVHIADV T H F V A P N S YI D I EAR T R A T TY YL A DR RYD MLP SV LS AD 176
Cdd:COG0557 247 DLR DLP LV - T ID GEDAK D F DD AV S AEK L D NG GWR LGVHIADV S H Y V R P G S AL D R EAR K R G T SV YL P DR VIP MLP ER LS NG 325
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 177 LCSL LG G V DR Y A V S IMW E L D KTS y E IKEVWYG R TI IRS AYK L F YE AA Q EL LDG N fsvvddipefkdld EKSRQAKLEE LV 256
Cdd:COG0557 326 LCSL NP G E DR L A M S CEM E I D AKG - E VVSYEFY R SV IRS DAR L T YE EV Q AI LDG K -------------- DEELREEYAD LV 390
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 257 WAIGK L TDI A RHV R AK R DGC GA LELEGV E VRVQ LD DKKNIH D LI P KQPLEV H ETVA E C M I LAN HW VA KKI - WESF P hq A L 335
Cdd:COG0557 391 PMLEE L YEL A KIL R KA R EKR GA IDFDLP E TKII LD EEGKPE D IV P RERNDA H KLIE E F M L LAN EA VA EFL e KLKL P -- F L 468
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 336 L R Q H PP P HQ E FFSE LRE CAKAK G FFI --- D TRSN K T L ADS L DNAND - P HDPIV N R - LLRSM A t QA M snal Y fstgsc AE E 410
Cdd:COG0557 469 Y R V H EE P DP E KLEA LRE FLANL G LKL kgg D EPTP K D L QKL L EQVKG r P EEELL N T l LLRSM K - QA V ---- Y ------ SP E 537
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 411 EFH H Y GLAL DK YTHFTSPIRRY S D IV VHR L L M A AISKDKKMEIKGN L ft NKD LEE LCR H INNRN R A A QHSQKQSTE L FQC 490
Cdd:COG0557 538 NIG H F GLAL EA YTHFTSPIRRY P D LL VHR A L K A YLEGKRSPGLQEY L -- EEE LEE IAE H CSETE R R A DEAERDVVD L KKA 615
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*..
gi 1622950836 491 M Y F KD K dpa TE E rc ISD GVI YSIRTN G VL V FIPRF G I kgaaylknk D GLV - I SS GP D 546
Cdd:COG0557 616 E Y M KD R --- VG E -- EFE GVI SGVTSF G LF V ELDEL G V --------- E GLV h V SS LG D 658
RNB
pfam00773 RNB domain; This domain is the catalytic domain of ribonuclease II.
95-445
3.97e-105
RNB domain; This domain is the catalytic domain of ribonuclease II.
Pssm-ID: 459934 [Multi-domain]
Cd Length: 314
Bit Score: 322.31
E-value: 3.97e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 95 RKDLR KS h LVFS IDP KGCE D V DD TL S IRT L N NG NLE LGVHIADV T H F V A P N S YI D I EAR T R A T TY YL A DR RYD MLP SV LS 174
Cdd:pfam00773 1 RKDLR DL - PFIT IDP ADAK D L DD AI S VEK L P NG GYR LGVHIADV S H Y V P P G S PL D R EAR K R G T SV YL P DR VIP MLP EK LS 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 175 A DLCSL LG G V DR Y A V S IMWEL D KT s Y E IKEVWYGRTI IRS AYK L F YE AAQE LL D G NFSVV D DIPEFK DL DE ksrqaklee 254
Cdd:pfam00773 80 N DLCSL NP G E DR L A L S VEITI D AD - G E VTSYEIYPSV IRS KAR L T YE EVDD LL E G KDAEK D KPDLAE DL RL --------- 149
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 255 lvwaigk L TDI A RHV RAKR DGC GAL E L EGV E VRVQ LD DKKN I h D LIPKQPLEV H ETVA E C M I LAN HW VA KKI w ESFPHQ A 334
Cdd:pfam00773 150 ------- L YEL A KIL RAKR LQR GAL D L DTP E NKLI LD EEGV I - D ILIQERTDA H SLIE E F M L LAN EA VA RHL - QELGIP A 220
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 335 L L R Q HP P P HQ E FFSE L RECAKAK gffidt RSN K T L AD SL DNAN D P hdpiv N RLL RSMATQA M SN A L Y FS tgscae E EFH H 414
Cdd:pfam00773 221 L Y R V HP E P DL E KLNS L IKLLQLL ------ PDD K G L SK SL EKIK D D ----- E RLL SILLLRT M PR A E Y SP ------ E PLG H 283
330 340 350
....*....|....*....|....*....|.
gi 1622950836 415 Y GL A LD K YTHFTSPIRRY S D IV VHR L L M A AI 445
Cdd:pfam00773 284 F GL G LD I YTHFTSPIRRY P D LI VHR Q L K A LL 314
RNB
smart00955 This domain is the catalytic domain of ribonuclease II;
95-447
3.10e-99
This domain is the catalytic domain of ribonuclease II;
Pssm-ID: 214935 [Multi-domain]
Cd Length: 286
Bit Score: 306.12
E-value: 3.10e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 95 R K DLR k SHLV F S IDP KGCE D V DD TL S IRT L N NG NLE LGVHIADV T H F V A P N S YI D I EAR T R A T TY YL A DR RYD MLP SV LS 174
Cdd:smart00955 1 R V DLR - DLPL F T IDP EDAK D I DD AV S VEK L D NG GYR LGVHIADV S H Y V K P G S AL D R EAR K R G T SV YL P DR VIP MLP EE LS 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 175 AD LCSL LG G V DR Y A V S IMWE LD KTSY EI KEVWYG R TI IRS AYK L F YE AAQEL L D gnfsvvddipefkdldeksrqaklee 254
Cdd:smart00955 80 NG LCSL NP G E DR L A L S VEMT LD ADGG EI LDYEFY R SV IRS KAR L T YE EVDAI L E -------------------------- 133
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 255 lvwaigkltdiarhvrakrdgcgalelegvev RVQ LD DKKN I H D LI P KQPLEV H ET V A E C MILAN HW VA KKIWESFP h QA 334
Cdd:smart00955 134 -------------------------------- KIV LD EEGK I E D IV P RERNDA H SL V E E F MILAN EA VA RFLAKNGI - PG 180
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 335 L L R Q H PP P HQ E FFS E - L R E CAKAK G FFI - DTRSN K T LA DS L DNAN D PHD piv N RLL RSMATQA M SN A L Y FSTG S caeeef 412
Cdd:smart00955 181 L Y R V H EG P DP E KLA E l L K E FLALL G LLL l GGDGP K A LA KL L EKIR D SPE --- E RLL ELLLLRS M PH A E Y SVDN S ------ 251
330 340 350
....*....|....*....|....*....|....*
gi 1622950836 413 H H Y GLALD K YTHFTSPIRRY S D IV VHR L L M AA ISK 447
Cdd:smart00955 252 G H F GLALD A YTHFTSPIRRY P D LI VHR Q L K AA LRG 286
RNase_R
TIGR02063 ribonuclease R; This family consists of an exoribonuclease, ribonuclease R, also called VacB. ...
22-546
5.49e-94
ribonuclease R; This family consists of an exoribonuclease, ribonuclease R, also called VacB. It is one of the eight exoribonucleases reported in E. coli and is broadly distributed throughout the bacteria. In E. coli, double mutants of this protein and polynucleotide phosphorylase are not viable. Scoring between trusted and noise cutoffs to the model are shorter, divergent forms from the Chlamydiae, and divergent forms from the Campylobacterales (including Helicobacter pylori) and Leptospira interrogans. [Transcription, Degradation of RNA]
Pssm-ID: 273947 [Multi-domain]
Cd Length: 709
Bit Score: 306.12
E-value: 5.49e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 22 V V V R I DSWESTSVYPN G HF V RV LG RIG D LEGE I AT I LVENS I s VIP F S E AQMC E mpvn TPEN P WK V SR EE EQK RKDLR KS 101
Cdd:TIGR02063 178 V L V E I TKYPDRNRPAI G KV V EI LG HAD D PGID I LI I IRKHG I - PYE F P E EVLD E ---- AAKI P EE V PE EE IKG RKDLR DL 252
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 102 h LVFS ID PKGCE D V DD TLSIRT L NN GN LE LGV H IADV T H F V APN S YI D I EA RT R A T TY YL A DR RYD MLP SV LS ADL CSL L 181
Cdd:TIGR02063 253 - PFVT ID GEDAK D F DD AVYVEK L KD GN YK LGV A IADV S H Y V REG S AL D K EA LK R G T SV YL P DR VIP MLP ER LS NGI CSL N 331
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 182 GGV DR YAV S IMW E L DK ---- TS YE IK E vwygr TI I R S AYK L F Y EAAQELLD G N fsvvddipef KD LD E K sr QAK L E E LVW 257
Cdd:TIGR02063 332 PNE DR LTL S CEM E I DK kgrv KK YE FY E ----- AV I N S HAR L T Y NQVNDIIE G K ---------- DA LD K K -- EPP L K E MLK 394
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 258 AIGK L TD I A R HV R A KR dgc GA LELEGV E VRVQ LD DKKNIH D LI P KQPLEV H ETVA E C MI L AN HW VA KKI w E SFPHQALL R 337
Cdd:TIGR02063 395 NLFE L YK I L R KK R K KR --- GA IDFDSK E AKII LD ENGKPI D IV P RERGDA H KLIE E F MI A AN ET VA EHL - E KAKLPFIY R 470
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 338 Q H PP P HQ E ---- FFSE L RECA - KA KG FFI D TRSN K TLADS L - DNAND P HDPIV N R - LLRSM A t QA M snaly F S T gscae E 410
Cdd:TIGR02063 471 V H ER P SE E klqn LREF L KTLG i TL KG GTS D KPQP K DFQKL L e KVKGR P EEELI N T v LLRSM Q - QA K ----- Y S P ----- E 539
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 411 EFH H Y GLAL DK YTHFTSPIRRY S D IV VHRL LMA A ISKDKK - MEI K GNLFTNKD LEE LCR H INNRN R A A QHSQKQSTELFQ 489
Cdd:TIGR02063 540 NIG H F GLAL EY YTHFTSPIRRY P D LI VHRL IKK A LFGGEN t TTE K EREYLEAK LEE IAE H SSKTE R R A DEAERDVNDWKK 619
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*...
gi 1622950836 490 CM Y FKD K dpate ERCISD GVI YSIRTN G VL V FIPRFG I kgaaylknk D GLV - IS SGP D 546
Cdd:TIGR02063 620 AE Y MSE K ----- IGEEFE GVI SGVTSF G LF V ELENNT I --------- E GLV h IS TLK D 663
3_prime_RNase
TIGR00358 VacB and RNase II family 3'-5' exoribonucleases; This model is defined to identify a pair of ...
20-586
9.38e-62
VacB and RNase II family 3'-5' exoribonucleases; This model is defined to identify a pair of paralogous 3-prime exoribonucleases in E. coli, plus the set of proteins apparently orthologous to one or the other in other eubacteria. VacB was characterized originally as required for the expression of virulence genes, but is now recognized as the exoribonuclease RNase R (Rnr). Its paralog in E. coli and H. influenzae is designated exoribonuclease II (Rnb). Both are involved in the degradation of mRNA, and consequently have strong pleiotropic effects that may be difficult to disentangle. Both these proteins share domain-level similarity (RNB, S1) with a considerable number of other proteins, and full-length similarity scoring below the trusted cutoff to proteins associated with various phenotypes but uncertain biochemistry; it may be that these latter proteins are also 3-prime exoribonucleases. [Transcription, Degradation of RNA]
Pssm-ID: 273033 [Multi-domain]
Cd Length: 654
Bit Score: 218.05
E-value: 9.38e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 20 FR VVV RIDSWESTSVYPN G HFVRV LG RIG D LEGEIATI L VENS I SVIPFS -- E A Q MCEMPVNTP E NPW K V sreeeqk R K D 97
Cdd:TIGR00358 124 DK VVV ELTEYPLRRNLFY G EITQI LG NND D PLIPWWVT L ARHE I PFEFPD gv E Q Q AAKLQFDVD E QAK K Y ------- R E D 196
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 98 L RKSHL V f S ID PKGCE D V DD TLSIRT L NN G NLE L G V H IADV THF VA P NS YI D I EA RT R ATTY YL ADRRYD MLP SV LS AD L 177
Cdd:TIGR00358 197 L TDLAF V - T ID GADAK D L DD AVYVKK L PD G GWK L Y V A IADV SYY VA E NS PL D K EA KH R GFSV YL PGFVIP MLP EE LS NG L 275
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 178 CSL LGGV DR YAVSIMWELDK ---- T SY E IKE vwygr TI I R S AYK L F Y eaaqelldgnf SV V D D IP E FK D l DEKSRQAK L E 253
Cdd:TIGR00358 276 CSL NPNE DR LVLVCEMTISA qgri T DN E FYP ----- AT I E S KAR L T Y ----------- DK V N D WL E ND D - ELQPEYET L V 338
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 254 E LVW A IGK L TDIARHV R A KR dgc G ALEL E GV E VRVQL D DKKNIH D LIPKQPLEVHETVA E C MI L AN HWV A KKIWESFPH q 333
Cdd:TIGR00358 339 E QLK A LHQ L SQALGEW R H KR --- G LIDF E HP E TKFIV D EEGRVI D IVAEVRRIAEKIIE E A MI V AN ICA A RFLHNHKVP - 414
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 334 ALL R Q HP P P HQEFFSE L R E CAKAK G ----- FFIDTRSNKTL A DS L DNAN D -- PHDPI V N RLLRS matqa M S N A L Y FS tgs 406
Cdd:TIGR00358 415 GIY R V HP G P SKKKLQS L L E FLAEL G ltlpg GNAENVTTLDG A CW L REVK D rp EYEIL V T RLLRS ----- L S Q A E Y SP --- 486
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 407 cae E EFH H Y GL A L DK Y T HFTSPIRRY S D IVV HRL LM A AIS K DKKME ik GNLFTNKD L EELCR H INNRN R A A QHSQKQSTE 486
Cdd:TIGR00358 487 --- E PLG H F GL G L EH Y A HFTSPIRRY P D LTN HRL IK A VLA K EQTDT -- ERYQPQDE L LQIAE H CSDTE R R A RDAERDVAD 561
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 487 LFQ C M Y FK DK DPAT eerci SD G V I Y S IRTN G VL V FIPRF GI kgaaylknk DGL V - IS SGPDSRSAWKP gsl QRFQNKITS 565
Cdd:TIGR00358 562 WLK C R Y LL DK VGTE ----- FS G E I S S VTRF G MF V RLDDN GI --------- DGL I h IS TLHNDYYVFDQ --- EKMALIGKG 624
570 580
....*....|....*....|.
gi 1622950836 566 T TT dgesv TFHLF D H VTV RIS 586
Cdd:TIGR00358 625 T GK ----- VYRIG D R VTV KLT 640
Rnb
COG4776 Exoribonuclease II [Transcription];
81-586
2.73e-36
Exoribonuclease II [Transcription];
Pssm-ID: 443808 [Multi-domain]
Cd Length: 644
Bit Score: 145.00
E-value: 2.73e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 81 PENP W KV s RE E EQK R K DL rk SH L V F - S ID PKGC ED V DD T L S I RT L N NG NLE L G V H IAD V T HFVAPN S YI D I EAR T RA T T Y 159
Cdd:COG4776 177 GDDE W EL - LD E GLE R E DL -- TA L P F v T ID SEST ED M DD A L Y I EK L E NG GWK L T V A IAD P T AYIPEG S EL D K EAR Q RA F T N 253
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 160 YL ADRRYD MLP SV LS A DLCSL LGGVD R Y A VSIMWEL D KT ----- SY E IKEV W ygrti IRS AY KL F Y EAAQEL L D G nfs VV 234
Cdd:COG4776 254 YL PGFNIP MLP RE LS D DLCSL KENEK R P A LVCRVTI D AD gsigd DI E FFAA W ----- IRS KA KL A Y DNVSDW L E G --- KG 325
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 235 DDI PE FKDLD E KS R Q akleelvwaigk L TDI A RHVRAK R DGCGALELEGVEV R VQ LD D K K N IH D LIPKQPLEVHET V A E C 314
Cdd:COG4776 326 EWQ PE NEEIA E QI R L ------------ L HQF A LARSQW R QQHALVFKDRPDY R FE LD E K G N VL D IHAEPRRIANRI V E E A 393
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 315 MI L AN HWV A K kiwesfphqa L LR Q H P ----- PP H QE F FS E LR E C A KA ----------------- K GF ----- FI D TRSNK 367
Cdd:COG4776 394 MI A AN ICA A R ---------- V LR E H L gfgif NV H SG F DP E KL E Q A VE llaehgiefdpeqlltl E GF calrr EL D AQPTS 463
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 368 T L a DS ldnandphdpivn RL L R SMATQAM S N alyfstgscae E EFH H Y GL A LD K Y THF TSPIR R Y S D I V V HRL LM A A I SK 447
Cdd:COG4776 464 Y L - DS ------------- RL R R FQTFAEI S T ----------- E PGP H F GL G LD A Y ATW TSPIR K Y G D M V N HRL IK A V I LG 518
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 448 DK kmeikgnlf TN K DL EEL CRHINN R N R AAQHSQKQSTELFQCM Y F K D K dp ATEERCISDGV I YSI R T -------- NG VL 519
Cdd:COG4776 519 QP --------- AE K PD EEL TERLAE R R R LNRMAERDVADWLYAR Y L K P K -- VGSGQVFTAEI I DIN R G glrvrlle NG AV 587
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622950836 520 V FIP rfgikg A AYL - KNK D G LV I S sgpdsrsa WKP G SLQ rfqnkitstt TD GE s V TFH L F D HVT V RIS 586
Cdd:COG4776 588 A FIP ------ A SFI h SVR D E LV C S -------- QEE G TVY ---------- IK GE - V RYK L G D TIQ V TLA 630
PRK11642
PRK11642 ribonuclease R;
52-449
3.67e-34
ribonuclease R;
Pssm-ID: 236944 [Multi-domain]
Cd Length: 813
Bit Score: 139.49
E-value: 3.67e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 52 G E I ATI L VE N --- SIS V -------- IP FS ----- E A Q MCEMPVNT PE npwkvsr E EEQK R K DLR KSH LV f S ID PKGCE D V 115
Cdd:PRK11642 208 G K I VEV L GD N mgt GMA V dialrthe IP YI wpqav E Q Q VAGLKEEV PE ------- E AKAG R V DLR DLP LV - T ID GEDAR D F 279
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 116 DD TLSIRTLNN G NLE L G V H IADV THF V A P NSYI D I EAR T R A T TY Y LADRRYD MLP S VLS AD LCSL LGG VDR ------ YAV 189
Cdd:PRK11642 280 DD AVYCEKKRG G GWR L W V A IADV SYY V R P PTPL D R EAR N R G T SV Y FPSQVVP MLP E VLS NG LCSL NPQ VDR lcmvce MTI 359
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 190 S IMWE L dk T S Y EIK E vwygr TIIR S AYK L F Y EAAQEL L D G NFSVVDDI - P EF K D L D E ksrqak L EE L V waig K LT D I AR H 268
Cdd:PRK11642 360 S SKGR L -- T G Y KFY E ----- AVMS S HAR L T Y TKVWHI L Q G DQDLREQY a P LV K H L E E ------ L HN L Y ---- K VL D K AR E 422
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 269 V R akrdgc G ALEL E GV E VRVQLDDKKN I HDLIPK Q PLEV H ETVA ECMILAN HWV A KKI w E SFPHQ AL L R Q H PP P HQ E FFS 348
Cdd:PRK11642 423 E R ------ G GISF E SE E AKFIFNAERR I ERIEQT Q RNDA H KLIE ECMILAN ISA A RFV - E KAKEP AL F R I H DK P ST E AIT 495
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 349 EL R ECAKAK G FFI --- DTRSNKTL A DS L DNAN D PH D piv NRL L RS M ATQA M SN A L Y fstgsc AE E EFH H Y GLAL DK Y T HF 425
Cdd:PRK11642 496 SF R SVLAEL G LEL pgg NKPEPRDY A EL L ESVA D RP D --- AEM L QT M LLRS M KQ A I Y ------ DP E NRG H F GLAL QS Y A HF 566
410 420
....*....|....*....|....
gi 1622950836 426 TSPIRRY S D IVV HR LLMAAIS K DK 449
Cdd:PRK11642 567 TSPIRRY P D LSL HR AIKYLLA K EQ 590
PRK05054
PRK05054 exoribonuclease II; Provisional
90-543
2.61e-27
exoribonuclease II; Provisional
Pssm-ID: 179920 [Multi-domain]
Cd Length: 644
Bit Score: 117.28
E-value: 2.61e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 90 E E EQK R K DL rk SH L V F - S ID PKGC ED V DD T L SIRT L NN G N L E L G V H IAD V T HFV A PN S YI D IE AR T RA T T Y YL ADRRYD M 168
Cdd:PRK05054 185 D E GLE R E DL -- TA L D F v T ID SAST ED M DD A L YVEK L PD G G L Q L T V A IAD P T AYI A EG S KL D KA AR Q RA F T N YL PGFNIP M 262
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 169 LP SV LS A DLCSL LGGVD R Y A VSIMWEL D KTSYEIKEVWYGRTI I R S AY KL F Y EAAQEL L DG nfs VV D DI PE FKDLD E KS R 248
Cdd:PRK05054 263 LP RE LS D DLCSL RPNER R P A LACRVTI D ADGTIEDDIRFFAAW I E S KA KL A Y DNVSDW L EN --- GG D WQ PE SEAIA E QI R 339
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 249 QAK leelvwaig KLTDIARHV R AKR dgcg AL EL - EGVEV R VQ L DD K KNIH D LIPKQPLEVHET V A E C MI L AN HWV A K kiw 327
Cdd:PRK05054 340 LLH --------- QFCLARSEW R KQH ---- AL VF k DRPDY R FE L GE K GEVL D IVAEPRRIANRI V E E S MI A AN ICA A R --- 403
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 328 esfphqa L LR QH ppphqeffselrecaka K GF F I ------- D TRSNKTLADS L DNANDPH D P ---------- IVN R L L RS 390
Cdd:PRK05054 404 ------- V LR DK ----------------- L GF G I ynvhsgf D PANAEQAVAL L KEHGLHF D A eelltlegfc KLR R E L DA 459
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 391 MA T QAMSNAL -- YF S TGSCAE E EFH H Y GL A L DK Y THF TSPIR R Y S D IVV HRLL M A A I SKDKKMEIK gnlftnkdl E E LCR 468
Cdd:PRK05054 460 QP T GYLDSRI rr FQ S FAEIST E PGP H F GL G L EA Y ATW TSPIR K Y G D MIN HRLL K A V I KGETAERPQ --------- D E ITV 530
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 469 HINN R N R AAQHSQKQSTELFQCM Y F KDK d PA T EE R C --- I S D ---- G VIYSIRT NG VLV FIP rfgikg A AY L - KNK D G LV 540
Cdd:PRK05054 531 QLAE R R R LNRMAERDVGDWLYAR Y L KDK - AG T DT R F aae I I D isrg G MRVRLLE NG AVA FIP ------ A SF L h AVR D E LV 603
...
gi 1622950836 541 ISS 543
Cdd:PRK05054 604 CNQ 606
OB_Dis3
pfam17849 Dis3-like cold-shock domain 2 (CSD2); This domain has an OB fold and is found in the Dis3l2 ...
17-62
5.67e-16
Dis3-like cold-shock domain 2 (CSD2); This domain has an OB fold and is found in the Dis3l2 protein. This domain along with CSD1 binds to RNA.
Pssm-ID: 436091 [Multi-domain]
Cd Length: 77
Bit Score: 73.03
E-value: 5.67e-16
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 1622950836 17 L QDFRV VV R ID S W EST S V YP N GH F V R VLG R IGD L E G E IAT IL V EN S 62
Cdd:pfam17849 32 L EGKLF VV K ID D W PEN S R YP L GH I V K VLG E IGD I E T E TEA IL L EN G 77
Rrp44_S1
pfam17215 S1 domain; This domain corresponds to the S1 domain found at the C-terminus of ribonucleases ...
511-588
4.23e-08
S1 domain; This domain corresponds to the S1 domain found at the C-terminus of ribonucleases such as yeast Rrp44.
Pssm-ID: 435792
Cd Length: 87
Bit Score: 50.99
E-value: 4.23e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622950836 511 Y S I RT -- NG VL VF I P R FGI K G AAY L KNKD G LVISSGP D S rsawkpgsl QRFQNKITSTTT d G ESV T FHL FD H V T VR ISVQ 588
Cdd:pfam17215 6 Y V I KV fn NG IV VF V P K FGI E G LIR L EDLT G DEPEAEF D A --------- DEYSLTFPDKGS - G KKR T VGV FD K V R VR VKSV 75
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
