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    ITGA2B integrin subunit alpha 2b [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 714955, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ITGA2Bprovided by VGNC
    Official Full Name
    integrin subunit alpha 2bprovided by VGNC
    Primary source
    VGNC:VGNC:73776
    See related
    Ensembl:ENSMMUG00000012659
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ITGA2B in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (55640817..55661346, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (50260060..50279672, complement)

    Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 171 member A2 Neighboring gene 60S ribosomal protein L7-like 1 Neighboring gene G-patch domain containing 8 Neighboring gene poly(rC)-binding protein 2 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables integrin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in angiogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell adhesion mediated by integrin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell-matrix adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in integrin-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of integrin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    integrin alpha-IIb
    Names
    integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041769.1 Reference Mmul_10 Primary Assembly

      Range
      55640817..55661346 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001114526.4 → XP_001114526.3  integrin alpha-IIb isoform X2

      UniProtKB/TrEMBL
      F7E7I7
      Related
      ENSMMUP00000016626.4, ENSMMUT00000017753.4
      Conserved Domains (3) summary
      smart00191
      Location:435 → 489
      Int_alpha; Integrin alpha (beta-propellor repeats)
      pfam00357
      Location:1071 → 1085
      Integrin_alpha; Integrin alpha cytoplasmic region
      pfam08441
      Location:532 → 972
      Integrin_alpha2; Integrin alpha

    2. XM_028836580.1 → XP_028692413.1  integrin alpha-IIb isoform X1

      Conserved Domains (2) summary
      smart00191
      Location:435 → 489
      Int_alpha; Integrin alpha (beta-propellor repeats)
      pfam08441
      Location:532 → 972
      Integrin_alpha2; Integrin alpha
    Nucleotide Protein
    Heading Accession and Version

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