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    ORC4 origin recognition complex subunit 4 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 721876, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ORC4provided by VGNC
    Official Full Name
    origin recognition complex subunit 4provided by VGNC
    Primary source
    VGNC:VGNC:75716
    See related
    Ensembl:ENSMMUG00000000043
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    ORC4L
    Orthologs
    human mouse all
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    Genomic context

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    See ORC4 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 12 NC_041765.1 (35096254..35186903, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 12 NC_027904.1 (34392947..34483624, complement)

    Chromosome 12 - NC_041765.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S3a pseudogene Neighboring gene U6 spliceosomal RNA Neighboring gene activin A receptor type 2A Neighboring gene 40S ribosomal protein S3a-like Neighboring gene methyl-CpG binding domain protein 5 Neighboring gene small nucleolar RNA SNORA48

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA replication origin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in DNA replication initiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of nuclear origin of replication recognition complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    origin recognition complex subunit 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041765.1 Reference Mmul_10 Primary Assembly

      Range
      35096254..35186903 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015110059.2 → XP_014965545.1  origin recognition complex subunit 4 isoform X1

      UniProtKB/TrEMBL
      F7HPF9, G7N816, H9ERG8
      Conserved Domains (2) summary
      COG1474
      Location:43 → 226
      CDC6; Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair]
      pfam14629
      Location:228 → 415
      ORC4_C; Origin recognition complex (ORC) subunit 4 C-terminus

    2. XM_015110063.2 → XP_014965549.1  origin recognition complex subunit 4 isoform X3

      UniProtKB/TrEMBL
      G7N816
      Conserved Domains (2) summary
      COG1474
      Location:43 → 226
      CDC6; Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair]
      pfam14629
      Location:228 → 386
      ORC4_C; Origin recognition complex (ORC) subunit 4 C-terminus

    3. XM_002798869.3 → XP_002798915.1  origin recognition complex subunit 4 isoform X5

      See identical proteins and their annotated locations for XP_002798915.1

      UniProtKB/TrEMBL
      A0A5F7ZW29
      Conserved Domains (2) summary
      COG1474
      Location:2 → 142
      CDC6; Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair]
      pfam14629
      Location:144 → 331
      ORC4_C; Origin recognition complex (ORC) subunit 4 C-terminus

    4. XM_015110064.2 → XP_014965550.1  origin recognition complex subunit 4 isoform X4

      UniProtKB/TrEMBL
      A0A5F7ZW29
      Related
      ENSMMUP00000069837.1, ENSMMUT00000089438.1
      Conserved Domains (2) summary
      COG1474
      Location:4 → 152
      CDC6; Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair]
      pfam14629
      Location:154 → 341
      ORC4_C; Origin recognition complex (ORC) subunit 4 C-terminus

    5. XM_015110062.2 → XP_014965548.1  origin recognition complex subunit 4 isoform X2

      UniProtKB/TrEMBL
      A0A5F8A651, G7N816
      Related
      ENSMMUP00000073358.1, ENSMMUT00000107973.1
      Conserved Domains (3) summary
      cd00009
      Location:30 → 197
      AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
      smart00382
      Location:45 → 201
      AAA; ATPases associated with a variety of cellular activities
      pfam14629
      Location:212 → 389
      ORC4_C; Origin recognition complex (ORC) subunit 4 C-terminus

    6. XM_015110061.2 → XP_014965547.1  origin recognition complex subunit 4 isoform X1

      UniProtKB/TrEMBL
      F7HPF9, G7N816, H9ERG8
      Related
      ENSMMUP00000000057.3, ENSMMUT00000000063.4
      Conserved Domains (2) summary
      COG1474
      Location:43 → 226
      CDC6; Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair]
      pfam14629
      Location:228 → 415
      ORC4_C; Origin recognition complex (ORC) subunit 4 C-terminus

    7. XM_015110060.2 → XP_014965546.1  origin recognition complex subunit 4 isoform X1

      UniProtKB/TrEMBL
      F7HPF9, G7N816, H9ERG8
      Conserved Domains (2) summary
      COG1474
      Location:43 → 226
      CDC6; Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair]
      pfam14629
      Location:228 → 415
      ORC4_C; Origin recognition complex (ORC) subunit 4 C-terminus

    8. XM_028830682.1 → XP_028686515.1  origin recognition complex subunit 4 isoform X1

      UniProtKB/TrEMBL
      F7HPF9, G7N816, H9ERG8
      Conserved Domains (2) summary
      COG1474
      Location:43 → 226
      CDC6; Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair]
      pfam14629
      Location:228 → 415
      ORC4_C; Origin recognition complex (ORC) subunit 4 C-terminus
    Nucleotide Protein
    Heading Accession and Version

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