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    EIF6 eukaryotic translation initiation factor 6 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 709602, updated on 17-Aug-2024

    Summary

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    Official Symbol
    EIF6provided by VGNC
    Official Full Name
    eukaryotic translation initiation factor 6provided by VGNC
    Primary source
    VGNC:VGNC:84765
    Locus tag
    EGK_02469
    See related
    Ensembl:ENSMMUG00000018208
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    ITGB4BP
    Orthologs
    human mouse all
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    Genomic context

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    See EIF6 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (70487807..70493677, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (28844239..28850109)

    Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107000422 Neighboring gene protein C receptor Neighboring gene matrix metallopeptidase 24 Neighboring gene uncharacterized LOC114670470 Neighboring gene MMP24 opposite strand Neighboring gene family with sequence similarity 83 member C Neighboring gene ubiquinol-cytochrome c reductase complex assembly factor 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ribosomal large subunit binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in assembly of large subunit precursor of preribosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cytosolic ribosome assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in maturation of 5.8S rRNA IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in maturation of LSU-rRNA IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in ribosomal subunit export from nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of preribosome, large subunit precursor IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    eukaryotic translation initiation factor 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041763.1 Reference Mmul_10 Primary Assembly

      Range
      70487807..70493677 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015149135.2 → XP_015004621.2  eukaryotic translation initiation factor 6 isoform X2

      Conserved Domains (1) summary
      cl00241
      Location:59 → 182
      IF6; Ribosome anti-association factor IF6 binds the large ribosomal subunit and prevents the two subunits from associating during translation initiation. IF6 comprises a family of translation factors that includes both eukaryotic (eIF6) and archeal (aIF6) ...

    2. XM_015149134.2 → XP_015004620.1  eukaryotic translation initiation factor 6 isoform X1

      UniProtKB/TrEMBL
      A0A1D5R862
      Conserved Domains (1) summary
      cl00241
      Location:1 → 182
      IF6; Ribosome anti-association factor IF6 binds the large ribosomal subunit and prevents the two subunits from associating during translation initiation. IF6 comprises a family of translation factors that includes both eukaryotic (eIF6) and archeal (aIF6) ...

    3. XM_028828350.1 → XP_028684183.1  eukaryotic translation initiation factor 6 isoform X1

      UniProtKB/TrEMBL
      A0A1D5R862
      Conserved Domains (1) summary
      cl00241
      Location:1 → 182
      IF6; Ribosome anti-association factor IF6 binds the large ribosomal subunit and prevents the two subunits from associating during translation initiation. IF6 comprises a family of translation factors that includes both eukaryotic (eIF6) and archeal (aIF6) ...

    4. XM_015149133.2 → XP_015004619.1  eukaryotic translation initiation factor 6 isoform X1

      UniProtKB/TrEMBL
      A0A1D5R862
      Conserved Domains (1) summary
      cl00241
      Location:1 → 182
      IF6; Ribosome anti-association factor IF6 binds the large ribosomal subunit and prevents the two subunits from associating during translation initiation. IF6 comprises a family of translation factors that includes both eukaryotic (eIF6) and archeal (aIF6) ...

    5. XM_015149132.2 → XP_015004618.1  eukaryotic translation initiation factor 6 isoform X1

      UniProtKB/TrEMBL
      A0A1D5R862
      Related
      ENSMMUP00000056502.2, ENSMMUT00000078732.2
      Conserved Domains (1) summary
      cl00241
      Location:1 → 182
      IF6; Ribosome anti-association factor IF6 binds the large ribosomal subunit and prevents the two subunits from associating during translation initiation. IF6 comprises a family of translation factors that includes both eukaryotic (eIF6) and archeal (aIF6) ...

    6. XM_015149136.2 → XP_015004622.1  eukaryotic translation initiation factor 6 isoform X3

      UniProtKB/TrEMBL
      A0A663DC57, A0A8J8Y1R9, F7AU95, G7N4Z7
      Conserved Domains (1) summary
      PTZ00136
      Location:1 → 244
      PTZ00136; eukaryotic translation initiation factor 6-like protein; Provisional

    7. XM_015149137.2 → XP_015004623.2  eukaryotic translation initiation factor 6 isoform X4

      Conserved Domains (1) summary
      cl00241
      Location:59 → 244
      IF6; Ribosome anti-association factor IF6 binds the large ribosomal subunit and prevents the two subunits from associating during translation initiation. IF6 comprises a family of translation factors that includes both eukaryotic (eIF6) and archeal (aIF6) ...

    8. XM_028828351.1 → XP_028684184.1  eukaryotic translation initiation factor 6 isoform X3

      UniProtKB/TrEMBL
      A0A663DC57, A0A8J8Y1R9, F7AU95, G7N4Z7
      Related
      ENSMMUP00000037792.3, ENSMMUT00000044772.3
      Conserved Domains (1) summary
      PTZ00136
      Location:1 → 244
      PTZ00136; eukaryotic translation initiation factor 6-like protein; Provisional
    Nucleotide Protein
    Heading Accession and Version

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