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    Zfp385c zinc finger protein 385C [ Mus musculus (house mouse) ]

    Gene ID: 278304, updated on 9-Dec-2024

    Summary

    Official Symbol
    Zfp385cprovided by MGI
    Official Full Name
    zinc finger protein 385Cprovided by MGI
    Primary source
    MGI:MGI:3608347
    See related
    Ensembl:ENSMUSG00000014198 AllianceGenome:MGI:3608347
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Znf385c; A930006D11Rik
    Summary
    Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to be active in nucleus. Orthologous to human ZNF385C (zinc finger protein 385C). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in testis adult (RPKM 25.5), large intestine adult (RPKM 12.2) and 27 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Zfp385c in Genome Data Viewer
    Location:
    11 D; 11 63.47 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (100517045..100583292, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (100626219..100692466, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:100443371-100443554 Neighboring gene 2',3'-cyclic nucleotide 3' phosphodiesterase Neighboring gene DnaJ heat shock protein family (Hsp40) member C7 Neighboring gene STARR-positive B cell enhancer ABC_E4000 Neighboring gene STARR-positive B cell enhancer ABC_E7061 Neighboring gene STARR-positive B cell enhancer ABC_E2369 Neighboring gene STARR-positive B cell enhancer ABC_E7062 Neighboring gene NFKB inhibitor interacting Ras-like protein 2 Neighboring gene chromosome 11 C17orf113 homolog Neighboring gene predicted gene, 38483 Neighboring gene STARR-positive B cell enhancer ABC_E7063 Neighboring gene STARR-positive B cell enhancer ABC_E9843 Neighboring gene DExH-box helicase 58 Neighboring gene K(lysine) acetyltransferase 2A

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001373887.1NP_001360816.1  zinc finger protein 385C isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL591469
      Conserved Domains (4) summary
      smart00451
      Location:4574
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:311379
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04988
      Location:378445
      AKAP95; A-kinase anchoring protein 95 (AKAP95)
      pfam12874
      Location:379402
      zf-met; Zinc-finger of C2H2 type
    2. NM_001373888.1NP_001360817.1  zinc finger protein 385C isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL591469
      Conserved Domains (4) summary
      smart00451
      Location:4574
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:310378
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04988
      Location:377444
      AKAP95; A-kinase anchoring protein 95 (AKAP95)
      pfam12874
      Location:378401
      zf-met; Zinc-finger of C2H2 type
    3. NM_001373889.1NP_001360818.1  zinc finger protein 385C isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL591469
      Conserved Domains (3) summary
      smart00451
      Location:4574
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:311379
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam12874
      Location:379402
      zf-met; Zinc-finger of C2H2 type
    4. NM_001373890.1NP_001360819.1  zinc finger protein 385C isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL591469
      Conserved Domains (3) summary
      sd00020
      Location:231299
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04988
      Location:298365
      AKAP95; A-kinase anchoring protein 95 (AKAP95)
      pfam12874
      Location:299322
      zf-met; Zinc-finger of C2H2 type
    5. NM_177790.4NP_808458.2  zinc finger protein 385C isoform 5

      See identical proteins and their annotated locations for NP_808458.2

      Status: VALIDATED

      Source sequence(s)
      AL591469
      Consensus CDS
      CCDS25430.1
      UniProtKB/Swiss-Prot
      A2A5E6, Q14AS5, Q8C8X1
      Related
      ENSMUSP00000099408.4, ENSMUST00000103119.10
      Conserved Domains (3) summary
      sd00020
      Location:230298
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04988
      Location:297364
      AKAP95; A-kinase anchoring protein 95 (AKAP95)
      pfam12874
      Location:298321
      zf-met; Zinc-finger of C2H2 type

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      100517045..100583292 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030246059.1XP_030101919.1  zinc finger protein 385C isoform X3

      Conserved Domains (4) summary
      smart00451
      Location:103132
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:369437
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04988
      Location:436503
      AKAP95; A-kinase anchoring protein 95 (AKAP95)
      pfam12874
      Location:437460
      zf-met; Zinc-finger of C2H2 type
    2. XM_030246056.1XP_030101916.1  zinc finger protein 385C isoform X2

      Conserved Domains (4) summary
      smart00451
      Location:132161
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:397465
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04988
      Location:464531
      AKAP95; A-kinase anchoring protein 95 (AKAP95)
      pfam12874
      Location:465488
      zf-met; Zinc-finger of C2H2 type
    3. XM_006533488.4XP_006533551.3  zinc finger protein 385C isoform X1

      Conserved Domains (4) summary
      smart00451
      Location:132161
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:398466
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04988
      Location:465532
      AKAP95; A-kinase anchoring protein 95 (AKAP95)
      pfam12874
      Location:466489
      zf-met; Zinc-finger of C2H2 type
    4. XM_006533492.5XP_006533555.1  zinc finger protein 385C isoform X4

      See identical proteins and their annotated locations for XP_006533555.1

      Conserved Domains (4) summary
      smart00451
      Location:4574
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:311379
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04988
      Location:378445
      AKAP95; A-kinase anchoring protein 95 (AKAP95)
      pfam12874
      Location:379402
      zf-met; Zinc-finger of C2H2 type
    5. XM_011249062.3XP_011247364.1  zinc finger protein 385C isoform X5

      Conserved Domains (3) summary
      sd00020
      Location:230298
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04988
      Location:297364
      AKAP95; A-kinase anchoring protein 95 (AKAP95)
      pfam12874
      Location:298321
      zf-met; Zinc-finger of C2H2 type
    6. XM_006533496.4XP_006533559.1  zinc finger protein 385C isoform X6

      Conserved Domains (3) summary
      sd00020
      Location:178246
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04988
      Location:245312
      AKAP95; A-kinase anchoring protein 95 (AKAP95)
      pfam12874
      Location:246269
      zf-met; Zinc-finger of C2H2 type