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ACA1 autoinhibited Ca2+-ATPase 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 839670, updated on 18-Sep-2024

Summary

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Official Symbol
ACA1
Official Full Name
autoinhibited Ca2+-ATPase 1
Primary source
TAIR:AT1G27770
Locus tag
AT1G27770
See related
Araport:AT1G27770
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
autoinhibited Ca2+-ATPase 1; CA2+-ATPASE; PEA1; PLASTID ENVELOPE ATPASE 1; T22C5.23; T22C5_23
Summary
Encodes a chloroplast envelope Ca2+-ATPase with an N-terminal autoinhibitor.
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Genomic context

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See ACA1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
8
Sequence:
Chromosome: 1; NC_003070.9 (9671632..9676307, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene nucleic acid binding protein Neighboring gene Ubiquitin system component Cue protein Neighboring gene interferon-related developmental regulator family protein / IFRD protein family Neighboring gene pseudo Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of a gene encoding a Ca(2+)-ATPase-like protein in the plastid envelope. Huang L, et al. Proc Natl Acad Sci U S A, 1993 Nov 1. PMID 8234257, Free PMC Article
  2. A calmodulin-stimulated Ca2+-ATPase from plant vacuolar membranes with a putative regulatory domain at its N-terminus. Malmström S, et al. FEBS Lett, 1997 Jan 6. PMID 9009223
  3. Genomic comparison of P-type ATPase ion pumps in Arabidopsis and rice. Baxter I, et al. Plant Physiol, 2003 Jun. PMID 12805592, Free PMC Article
  4. Genes encoding calmodulin-binding proteins in the Arabidopsis genome. Reddy VS, et al. J Biol Chem, 2002 Mar 22. PMID 11782485
  5. Mapping the Arabidopsis organelle proteome. Dunkley TP, et al. Proc Natl Acad Sci U S A, 2006 Apr 25. PMID 16618929, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

NM_102542.1
NM_179385.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables P-type calcium transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables P-type calcium transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables P-type calcium transporter activity TAS
Traceable Author Statement
more info
 PubMed 
enables calcium channel activity TAS
Traceable Author Statement
more info
 PubMed 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
  
enables calmodulin binding TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in chloroplast inner membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in chloroplast inner membrane TAS
Traceable Author Statement
more info
 PubMed 
located_in endoplasmic reticulum HDA PubMed 
located_in nucleus HDA PubMed 

General protein information

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Preferred Names
autoinhibited Ca2+-ATPase 1
NP_564295.1
  • autoinhibited Ca2+-ATPase 1 (ACA1); FUNCTIONS IN: calcium channel activity, calcium-transporting ATPase activity, calmodulin binding; INVOLVED IN: cation transport, calcium ion transport, ATP biosynthetic process; LOCATED IN: endoplasmic reticulum, plasma membrane, chloroplast inner membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, P-type, ATPase-associated domain (InterPro:IPR008250), ATPase, P-type, calcium-transporting, PMCA-type (InterPro:IPR006408), ATPase, P-type cation-transporter, N-terminal (InterPro:IPR004014), ATPase, P-type cation exchange, alpha subunit (InterPro:IPR006069), ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter (InterPro:IPR001757), ATPase, P-type phosphorylation site (InterPro:IPR018303), ATPase, P-type cation-transporter, C-terminal (InterPro:IPR006068); BEST Arabidopsis thaliana protein match is: calcium ATPase 2 (TAIR:AT4G37640.1); Has 48793 Blast hits to 33205 proteins in 3149 species: Archae - 856; Bacteria - 30326; Metazoa - 5666; Fungi - 3781; Plants - 2732; Viruses - 4; Other Eukaryotes - 5428 (source: NCBI BLink).
NP_849716.1
  • autoinhibited Ca2+-ATPase 1 (ACA1); FUNCTIONS IN: calcium channel activity, calcium-transporting ATPase activity, calmodulin binding; INVOLVED IN: cation transport, calcium ion transport, metabolic process, ATP biosynthetic process; LOCATED IN: endoplasmic reticulum, plasma membrane, chloroplast inner membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, P-type, ATPase-associated domain (InterPro:IPR008250), ATPase, P-type, calcium-transporting, PMCA-type (InterPro:IPR006408), Haloacid dehalogenase-like hydrolase (InterPro:IPR005834), ATPase, P-type cation-transporter, N-terminal (InterPro:IPR004014), ATPase, P-type, H+ transporting proton pump (InterPro:IPR000695), ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter (InterPro:IPR001757), ATPase, P-type cation-transporter, C-terminal (InterPro:IPR006068), ATPase, P-type phosphorylation site (InterPro:IPR018303); BEST Arabidopsis thaliana protein match is: calcium ATPase 2 (TAIR:AT4G37640.1); Has 48177 Blast hits to 34612 proteins in 3273 species: Archae - 915; Bacteria - 33514; Metazoa - 4128; Fungi - 2798; Plants - 2164; Viruses - 3; Other Eukaryotes - 4655 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    9671632..9676307 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001332786.1 → NP_001321521.1  autoinhibited Ca2+-ATPase 1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8AR51

  2. NM_001332787.1 → NP_001321522.1  autoinhibited Ca2+-ATPase 1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q37145, Q37146, Q42571, Q42587, Q9SFY1
    UniProtKB/TrEMBL
    A0A178WD16, A0A5S9W3P6
    Conserved Domains (2) summary
    TIGR01517
    Location:59 → 1017
    ATPase-IIB_Ca; plasma-membrane calcium-translocating P-type ATPase
    pfam12515
    Location:5 → 50
    CaATP_NAI; Ca2+-ATPase N terminal autoinhibitory domain

  3. NM_179385.2 → NP_849716.1  autoinhibited Ca2+-ATPase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_849716.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q37145, Q37146, Q42571, Q42587, Q9SFY1
    UniProtKB/TrEMBL
    A0A178WD16, A0A5S9W3P6
    Conserved Domains (2) summary
    TIGR01517
    Location:59 → 1017
    ATPase-IIB_Ca; plasma-membrane calcium-translocating P-type ATPase
    pfam12515
    Location:5 → 50
    CaATP_NAI; Ca2+-ATPase N terminal autoinhibitory domain

  4. NM_102542.1 → NP_564295.1  autoinhibited Ca2+-ATPase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_564295.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4HUS8
    Conserved Domains (7) summary
    COG4087
    Location:639 → 719
    COG4087; Soluble P-type ATPase [General function prediction only]
    TIGR01517
    Location:59 → 943
    ATPase-IIB_Ca; plasma-membrane calcium-translocating P-type ATPase
    pfam00122
    Location:206 → 445
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:768 → 941
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam00690
    Location:118 → 186
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    pfam12515
    Location:5 → 50
    CaATP_NAI; Ca2+-ATPase N terminal autoinhibitory domain
    pfam13246
    Location:512 → 594
    Cation_ATPase; Cation transport ATPase (P-type)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q37145.3

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