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ACA1 autoinhibited Ca2+-ATPase 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 839670, updated on 18-Sep-2024

Summary

Official Symbol
ACA1
Official Full Name
autoinhibited Ca2+-ATPase 1
Primary source
TAIR:AT1G27770
Locus tag
AT1G27770
See related
Araport:AT1G27770
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
autoinhibited Ca2+-ATPase 1; CA2+-ATPASE; PEA1; PLASTID ENVELOPE ATPASE 1; T22C5.23; T22C5_23
Summary
Encodes a chloroplast envelope Ca2+-ATPase with an N-terminal autoinhibitor.
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Genomic context

See ACA1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
8
Sequence:
Chromosome: 1; NC_003070.9 (9671632..9676307, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene nucleic acid binding protein Neighboring gene Ubiquitin system component Cue protein Neighboring gene interferon-related developmental regulator family protein / IFRD protein family Neighboring gene pseudo Neighboring gene pseudo

General gene information

NM_102542.1
NM_179385.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ATP hydrolysis activity  
enables P-type calcium transporter activity  
enables P-type calcium transporter activity PubMed 
enables P-type calcium transporter activity PubMed 
enables calcium channel activity PubMed 
enables calmodulin binding  
enables calmodulin binding PubMed 

General protein information

Preferred Names
autoinhibited Ca2+-ATPase 1
NP_564295.1
  • autoinhibited Ca2+-ATPase 1 (ACA1); FUNCTIONS IN: calcium channel activity, calcium-transporting ATPase activity, calmodulin binding; INVOLVED IN: cation transport, calcium ion transport, ATP biosynthetic process; LOCATED IN: endoplasmic reticulum, plasma membrane, chloroplast inner membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, P-type, ATPase-associated domain (InterPro:IPR008250), ATPase, P-type, calcium-transporting, PMCA-type (InterPro:IPR006408), ATPase, P-type cation-transporter, N-terminal (InterPro:IPR004014), ATPase, P-type cation exchange, alpha subunit (InterPro:IPR006069), ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter (InterPro:IPR001757), ATPase, P-type phosphorylation site (InterPro:IPR018303), ATPase, P-type cation-transporter, C-terminal (InterPro:IPR006068); BEST Arabidopsis thaliana protein match is: calcium ATPase 2 (TAIR:AT4G37640.1); Has 48793 Blast hits to 33205 proteins in 3149 species: Archae - 856; Bacteria - 30326; Metazoa - 5666; Fungi - 3781; Plants - 2732; Viruses - 4; Other Eukaryotes - 5428 (source: NCBI BLink).
NP_849716.1
  • autoinhibited Ca2+-ATPase 1 (ACA1); FUNCTIONS IN: calcium channel activity, calcium-transporting ATPase activity, calmodulin binding; INVOLVED IN: cation transport, calcium ion transport, metabolic process, ATP biosynthetic process; LOCATED IN: endoplasmic reticulum, plasma membrane, chloroplast inner membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, P-type, ATPase-associated domain (InterPro:IPR008250), ATPase, P-type, calcium-transporting, PMCA-type (InterPro:IPR006408), Haloacid dehalogenase-like hydrolase (InterPro:IPR005834), ATPase, P-type cation-transporter, N-terminal (InterPro:IPR004014), ATPase, P-type, H+ transporting proton pump (InterPro:IPR000695), ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter (InterPro:IPR001757), ATPase, P-type cation-transporter, C-terminal (InterPro:IPR006068), ATPase, P-type phosphorylation site (InterPro:IPR018303); BEST Arabidopsis thaliana protein match is: calcium ATPase 2 (TAIR:AT4G37640.1); Has 48177 Blast hits to 34612 proteins in 3273 species: Archae - 915; Bacteria - 33514; Metazoa - 4128; Fungi - 2798; Plants - 2164; Viruses - 3; Other Eukaryotes - 4655 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    9671632..9676307 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001332786.1NP_001321521.1  autoinhibited Ca2+-ATPase 1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8AR51
  2. NM_001332787.1NP_001321522.1  autoinhibited Ca2+-ATPase 1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q37145, Q37146, Q42571, Q42587, Q9SFY1
    UniProtKB/TrEMBL
    A0A178WD16, A0A5S9W3P6
    Conserved Domains (2) summary
    TIGR01517
    Location:591017
    ATPase-IIB_Ca; plasma-membrane calcium-translocating P-type ATPase
    pfam12515
    Location:550
    CaATP_NAI; Ca2+-ATPase N terminal autoinhibitory domain
  3. NM_179385.2NP_849716.1  autoinhibited Ca2+-ATPase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_849716.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q37145, Q37146, Q42571, Q42587, Q9SFY1
    UniProtKB/TrEMBL
    A0A178WD16, A0A5S9W3P6
    Conserved Domains (2) summary
    TIGR01517
    Location:591017
    ATPase-IIB_Ca; plasma-membrane calcium-translocating P-type ATPase
    pfam12515
    Location:550
    CaATP_NAI; Ca2+-ATPase N terminal autoinhibitory domain
  4. NM_102542.1NP_564295.1  autoinhibited Ca2+-ATPase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_564295.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4HUS8
    Conserved Domains (7) summary
    COG4087
    Location:639719
    COG4087; Soluble P-type ATPase [General function prediction only]
    TIGR01517
    Location:59943
    ATPase-IIB_Ca; plasma-membrane calcium-translocating P-type ATPase
    pfam00122
    Location:206445
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:768941
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam00690
    Location:118186
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    pfam12515
    Location:550
    CaATP_NAI; Ca2+-ATPase N terminal autoinhibitory domain
    pfam13246
    Location:512594
    Cation_ATPase; Cation transport ATPase (P-type)
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