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PLDDELTA phospholipase D delta [ Arabidopsis thaliana (thale cress) ]

Gene ID: 829733, updated on 18-Sep-2024

Summary

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Official Symbol
PLDDELTA
Official Full Name
phospholipase D delta
Primary source
TAIR:AT4G35790
Locus tag
AT4G35790
See related
Araport:AT4G35790
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ARABIDOPSIS THALIANA PHOSPHOLIPASE D DELTA; ATPLDDELTA; F4B14.60; F4B14_60; PHOSPHOLIPASE D; phospholipase D delta
Summary
Encodes a protein with phospholipase D activity. Involved in phospolipase metabolism. Mutants are affected in hydrogen peroxide mediated cell death.
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Genomic context

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See PLDDELTA in Genome Data Viewer
Location:
chromosome: 4
Exon count:
10
Sequence:
Chromosome: 4; NC_003075.7 (16955415..16960407, complement)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene RNA-binding (RRM/RBD/RNP motifs) family protein Neighboring gene ROTUNDIFOLIA like 6 Neighboring gene RNA polymerase II large subunit Neighboring gene 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The plasma membrane-bound phospholipase Ddelta enhances freezing tolerance in Arabidopsis thaliana. Li W, et al. Nat Biotechnol, 2004 Apr. PMID 15004566
  2. Phospholipase Dδ regulates pollen tube growth by modulating actin cytoskeleton organization in Arabidopsis. Jia Q, et al. Plant Signal Behav, 2021 Jul 3. PMID 33853512, Free PMC Article
  3. Osmotic stress-triggered stomatal closure requires Phospholipase Dδ and hydrogen sulfide in Arabidopsis thaliana. Liu Q, et al. Biochem Biophys Res Commun, 2021 Jan 1. PMID 33187643
  4. Involvement of Arabidopsis phospholipase D δ in regulation of ROS-mediated microtubule organization and stomatal movement upon heat shock. Song P, et al. J Exp Bot, 2020 Oct 22. PMID 32725150
  5. Secretion of Phospholipase Dδ Functions as a Regulatory Mechanism in Plant Innate Immunity. Xing J, et al. Plant Cell, 2019 Dec. PMID 31597687, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Populus euphratica GLABRA3 Binds PLDdelta Promoters to Enhance Salt Tolerance.
    Title: Populus euphratica GLABRA3 Binds PLDδ Promoters to Enhance Salt Tolerance.
  2. Phosphatidic acid modulates MPK3- and MPK6-mediated hypoxia signaling in Arabidopsis.
    Title: Phosphatidic acid modulates MPK3- and MPK6-mediated hypoxia signaling in Arabidopsis.
  3. Phospholipase Ddelta regulates pollen tube growth by modulating actin cytoskeleton organization in Arabidopsis.
    Title: Phospholipase Dδ regulates pollen tube growth by modulating actin cytoskeleton organization in Arabidopsis.
  4. Involvement of Arabidopsis phospholipase D delta in regulation of ROS-mediated microtubule organization and stomatal movement upon heat shock.
    Title: Involvement of Arabidopsis phospholipase D δ in regulation of ROS-mediated microtubule organization and stomatal movement upon heat shock.
  5. Osmotic stress-triggered stomatal closure requires Phospholipase Ddelta and hydrogen sulfide in Arabidopsis thaliana.
    Title: Osmotic stress-triggered stomatal closure requires Phospholipase Dδ and hydrogen sulfide in Arabidopsis thaliana.
  6. The translocation of PLDdelta to papillae is modulated by exocytosis, thus triggering phosphatidic acid-mediated signaling in plant innate immunity.
    Title: Secretion of Phospholipase Dδ Functions as a Regulatory Mechanism in Plant Innate Immunity.
  7. The results demonstrate that PLDalpha1 and PLDdelta oppositely modulate basal, post-penetration resistance against powdery mildew through a non-canonical mechanism that is independent of EDS1/PAD4, SA, and JA.
    Title: Arabidopsis phospholipase Dα1 and Dδ oppositely modulate EDS1- and SA-independent basal resistance against adapted powdery mildew.
  8. PLDdelta negatively regulates plant thermotolerance via destabilizing cortical microtubules.
    Title: Phospholipase Dδ negatively regulates plant thermotolerance by destabilizing cortical microtubules in Arabidopsis.
  9. in wt plants PLDdelta disrupt membranes in severe drought stress and, in the absence of the protein (PLDdelta knock-out) might drought-prime the plants, making them more tolerant to severe drought stress.
    Title: Phospholipase D δ knock-out mutants are tolerant to severe drought stress.
  10. PLD is involved in defense signaling in nonhost resistance against powdery mildew fungi and PLDdelta is the main isoform participating in this process.
    Title: Arabidopsis phospholipase dδ is involved in basal defense and nonhost resistance to powdery mildew fungi.
Submit: New GeneRIF Correction See all GeneRIFs (15)

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_119745.3
NM_179170.3
NM_179171.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables N-acylphosphatidylethanolamine-specific phospholipase D activity IEA
Inferred from Electronic Annotation
more info
  
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables phospholipase D activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables phospholipase D activity IEA
Inferred from Electronic Annotation
more info
  
enables phospholipase D activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables phospholipase D activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within phosphatidic acid metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in phosphatidylcholine metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within positive regulation of abscisic acid-activated signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within programmed cell death IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of stomatal closure IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to cold IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within response to cold IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
colocalizes_with microtubule cytoskeleton TAS
Traceable Author Statement
more info
 PubMed 
located_in plant cell papilla IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plant-type vacuole HDA PubMed 
located_in plasma membrane HDA PubMed 
colocalizes_with plasma membrane TAS
Traceable Author Statement
more info
 PubMed 
located_in plasma membrane region IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasmodesma HDA PubMed 

General protein information

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Preferred Names
phospholipase D delta
NP_567989.1
  • phospholipase D delta (PLDDELTA); FUNCTIONS IN: phospholipase D activity; INVOLVED IN: response to water deprivation, response to cold, hyperosmotic salinity response, phosphatidic acid metabolic process, programmed cell death; LOCATED IN: microtubule cytoskeleton, plasma membrane, vacuole, membrane; EXPRESSED IN: 31 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: C2 membrane targeting protein (InterPro:IPR018029), C2 calcium/lipid-binding domain, CaLB (InterPro:IPR008973), Phospholipase D (InterPro:IPR015679), Phospholipase D, plant (InterPro:IPR011402), Phospholipase D/Transphosphatidylase (InterPro:IPR001736), C2 calcium-dependent membrane targeting (InterPro:IPR000008); BEST Arabidopsis thaliana protein match is: phospholipase D beta 1 (TAIR:AT2G42010.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
NP_849501.1
  • ARABIDOPSIS THALIANA PHOSPHOLIPASE D DELTA (ATPLDDELTA); FUNCTIONS IN: phospholipase D activity; INVOLVED IN: response to water deprivation, response to cold, hyperosmotic salinity response, phosphatidic acid metabolic process, programmed cell death; LOCATED IN: microtubule cytoskeleton, plasma membrane, vacuole, membrane; EXPRESSED IN: 31 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: C2 membrane targeting protein (InterPro:IPR018029), C2 calcium/lipid-binding domain, CaLB (InterPro:IPR008973), Phospholipase D (InterPro:IPR015679), Phospholipase D, plant (InterPro:IPR011402), Phospholipase D/Transphosphatidylase (InterPro:IPR001736), C2 calcium-dependent membrane targeting (InterPro:IPR000008); BEST Arabidopsis thaliana protein match is: phospholipase D beta 1 (TAIR:AT2G42010.1); Has 2426 Blast hits to 1986 proteins in 434 species: Archae - 0; Bacteria - 499; Metazoa - 513; Fungi - 443; Plants - 789; Viruses - 0; Other Eukaryotes - 182 (source: NCBI BLink).
NP_849502.1
  • ARABIDOPSIS THALIANA PHOSPHOLIPASE D DELTA (ATPLDDELTA); FUNCTIONS IN: phospholipase D activity; INVOLVED IN: response to water deprivation, response to cold, hyperosmotic salinity response, phosphatidic acid metabolic process, programmed cell death; LOCATED IN: microtubule cytoskeleton, plasma membrane, vacuole, membrane; EXPRESSED IN: 31 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: C2 membrane targeting protein (InterPro:IPR018029), C2 calcium/lipid-binding domain, CaLB (InterPro:IPR008973), Phospholipase D (InterPro:IPR015679), Phospholipase D, plant (InterPro:IPR011402), Phospholipase D/Transphosphatidylase (InterPro:IPR001736), C2 calcium-dependent membrane targeting (InterPro:IPR000008); BEST Arabidopsis thaliana protein match is: phospholipase D beta 1 (TAIR:AT2G42010.1); Has 2145 Blast hits to 1885 proteins in 404 species: Archae - 0; Bacteria - 362; Metazoa - 509; Fungi - 323; Plants - 775; Viruses - 0; Other Eukaryotes - 176 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    16955415..16960407 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_179170.3 → NP_849501.1  phospholipase D delta [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_849501.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178UUU1
    Conserved Domains (1) summary
    PLN03008
    Location:1 → 857
    PLN03008; Phospholipase D delta

  2. NM_179171.2 → NP_849502.1  phospholipase D delta [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_849502.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4JNU6
    Conserved Domains (2) summary
    cd04015
    Location:9 → 177
    C2_plant_PLD; C2 domain present in plant phospholipase D (PLD)
    cl15239
    Location:231 → 408
    PLDc_SF; Catalytic domain of phospholipase D superfamily proteins

  3. NM_119745.3 → NP_567989.1  phospholipase D delta [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_567989.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q0WUE7, Q8L891, Q944P8, Q947R2, Q9C5Y0, Q9FS18, Q9SZS7
    UniProtKB/TrEMBL
    A0A5S9XYZ0
    Conserved Domains (1) summary
    PLN03008
    Location:1 → 868
    PLN03008; Phospholipase D delta
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9C5Y0.2

Gene LinkOut

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