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TYRDC L-tyrosine decarboxylase [ Arabidopsis thaliana (thale cress) ]

Gene ID: 828986, updated on 18-Sep-2024

Summary

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Official Symbol
TYRDC
Official Full Name
L-tyrosine decarboxylase
Primary source
TAIR:AT4G28680
Locus tag
AT4G28680
See related
Araport:AT4G28680
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AtTYDC; L-tyrosine decarboxylase; L-TYROSINE DECARBOXYLASE 1; T5F17.130; T5F17_130; TYDC; TYRDC1
Summary
Encodes a stress-induced tyrosine decarboxylase (TyrDC). Recombinant (His)6-TyrDC expressed in E. coli catalyzes the conversion of L-tyrosine to tyramine. Recombinant TyrDC forms tetramers.
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Genomic context

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See TYRDC in Genome Data Viewer
Location:
chromosome: 4
Exon count:
11
Sequence:
Chromosome: 4; NC_003075.7 (14155064..14158869)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene photosystem II reaction center PSB28 protein Neighboring gene cysteine-rich RECEPTOR-like kinase, putative (DUF26) Neighboring gene uncharacterized protein Neighboring gene ammonium transporter 1;4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Gene expression and characterization of a stress-induced tyrosine decarboxylase from Arabidopsis thaliana. Lehmann T, et al. FEBS Lett, 2009 Jun 18. PMID 19450582
  2. Role of aromatic aldehyde synthase in wounding/herbivory response and flower scent production in different Arabidopsis ecotypes. Gutensohn M, et al. Plant J, 2011 May. PMID 21284755
  3. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. TYDC knock-out mutants are deficient in tyramine synthesis.
    Title: Role of aromatic aldehyde synthase in wounding/herbivory response and flower scent production in different Arabidopsis ecotypes.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

NM_001084992.1
NM_119010.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables aromatic-L-amino-acid decarboxylase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
  
enables tyrosine decarboxylase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables tyrosine decarboxylase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in amino acid metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in carboxylic acid metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within response to water deprivation IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within response to wounding IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within tyramine biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
L-tyrosine decarboxylase
NP_001078461.1
  • L-tyrosine decarboxylase (TYRDC); CONTAINS InterPro DOMAIN/s: Aromatic-L-amino-acid decarboxylase (InterPro:IPR010977), Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Pyridoxal phosphate-dependent decarboxylase (InterPro:IPR002129), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (InterPro:IPR015422); BEST Arabidopsis thaliana protein match is: Pyridoxal phosphate (PLP)-dependent transferases superfamily protein (TAIR:AT2G20340.1); Has 8315 Blast hits to 6320 proteins in 1946 species: Archae - 163; Bacteria - 2600; Metazoa - 2483; Fungi - 771; Plants - 335; Viruses - 8; Other Eukaryotes - 1955 (source: NCBI BLink).
NP_001190861.1
  • L-tyrosine decarboxylase (TYRDC); CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Aromatic-L-amino-acid decarboxylase (InterPro:IPR010977), Pyridoxal phosphate-dependent decarboxylase (InterPro:IPR002129), Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (InterPro:IPR015422), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421); BEST Arabidopsis thaliana protein match is: Pyridoxal phosphate (PLP)-dependent transferases superfamily protein (TAIR:AT2G20340.1).
NP_001190862.1
  • L-tyrosine decarboxylase (TYRDC); CONTAINS InterPro DOMAIN/s: Aromatic-L-amino-acid decarboxylase (InterPro:IPR010977), Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Pyridoxal phosphate-dependent decarboxylase (InterPro:IPR002129), Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (InterPro:IPR015422), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421); BEST Arabidopsis thaliana protein match is: Pyridoxal phosphate (PLP)-dependent transferases superfamily protein (TAIR:AT2G20340.1).
NP_194597.1
  • L-tyrosine decarboxylase (TYRDC); CONTAINS InterPro DOMAIN/s: Aromatic-L-amino-acid decarboxylase (InterPro:IPR010977), Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Pyridoxal phosphate-dependent decarboxylase (InterPro:IPR002129), Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (InterPro:IPR015422), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421); BEST Arabidopsis thaliana protein match is: Pyridoxal phosphate (PLP)-dependent transferases superfamily protein (TAIR:AT2G20340.1); Has 8292 Blast hits to 6272 proteins in 1930 species: Archae - 160; Bacteria - 2569; Metazoa - 2508; Fungi - 762; Plants - 340; Viruses - 8; Other Eukaryotes - 1945 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    14155064..14158869
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001341927.1 → NP_001329473.1  L-tyrosine decarboxylase [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8B7T4, A0A5S9XX47, A0A654FU52
    Conserved Domains (1) summary
    PLN02590
    Location:2 → 566
    PLN02590; probable tyrosine decarboxylase

  2. NM_001341929.1 → NP_001329472.1  L-tyrosine decarboxylase [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8B7T5
    Conserved Domains (1) summary
    cl18945
    Location:2 → 388
    AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...

  3. NM_001203933.2 → NP_001190862.1  L-tyrosine decarboxylase [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001190862.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A654FU52, F4JM08
    Conserved Domains (1) summary
    PLN02590
    Location:2 → 538
    PLN02590; probable tyrosine decarboxylase

  4. NM_001341928.1 → NP_001329474.1  L-tyrosine decarboxylase [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8B7T7

  5. NM_001203932.1 → NP_001190861.1  L-tyrosine decarboxylase [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001190861.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A654FU52, F4JM09
    Conserved Domains (1) summary
    PLN02590
    Location:7 → 547
    PLN02590; probable tyrosine decarboxylase

  6. NM_001084992.1 → NP_001078461.1  L-tyrosine decarboxylase [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001078461.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A654FU52, A8MQJ1
    Conserved Domains (1) summary
    PLN02590
    Location:7 → 547
    PLN02590; probable tyrosine decarboxylase

  7. NM_119010.3 → NP_194597.1  L-tyrosine decarboxylase [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_194597.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9M0G4
    UniProtKB/TrEMBL
    A0A654FU52
    Conserved Domains (1) summary
    PLN02590
    Location:7 → 545
    PLN02590; probable tyrosine decarboxylase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9M0G4.1

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