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VDAC5 voltage dependent anion channel 5 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 824154, updated on 18-Sep-2024

Summary

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Official Symbol
VDAC5
Official Full Name
voltage dependent anion channel 5
Primary source
TAIR:AT3G49920
Locus tag
AT3G49920
See related
Araport:AT3G49920
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ARABIDOPSIS THALIANA VOLTAGE DEPENDENT ANION CHANNEL 5; ATVDAC5; F3A4.1; voltage dependent anion channel 5
Summary
Encodes a voltage-dependent anion channel (VDAC: AT3G01280/VDAC1, AT5G67500/VDAC2, AT5G15090/VDAC3, AT5G57490/VDAC4, AT5G15090/VDAC5). VDACs are reported to be porin-type, beta-barrel diffusion pores. They are prominently localized in the outer mitochondrial membrane and are involved in metabolite exchange between the organelle and the cytosol.
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Genomic context

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See VDAC5 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
6
Sequence:
Chromosome: 3; NC_003074.8 (18505481..18507835, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Phototropic-responsive NPH3 family protein Neighboring gene ncRNA Neighboring gene Translation protein SH3-like family protein Neighboring gene tRNA-Val Neighboring gene C2H2 and C2HC zinc fingers superfamily protein Neighboring gene LOB domain-containing protein 38

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
  2. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001203116.2
NM_114852.1

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables voltage-gated monoatomic anion channel activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in monoatomic anion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in mitochondrial outer membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
voltage dependent anion channel 5
NP_001319718.1
  • voltage dependent anion channel 5 (VDAC5); FUNCTIONS IN: voltage-gated anion channel activity; INVOLVED IN: anion transport, transmembrane transport; LOCATED IN: mitochondrial outer membrane; EXPRESSED IN: 7 plant structures; EXPRESSED DURING: petal differentiation and expansion stage, E expanded cotyledon stage; CONTAINS InterPro DOMAIN/s: Porin, eukaryotic type (InterPro:IPR001925); BEST Arabidopsis thaliana protein match is: voltage dependent anion channel 2 (TAIR:AT5G67500.1).
NP_190561.1
  • voltage dependent anion channel 5 (VDAC5); FUNCTIONS IN: voltage-gated anion channel activity; INVOLVED IN: anion transport, transmembrane transport; LOCATED IN: mitochondrial outer membrane; EXPRESSED IN: 7 plant structures; EXPRESSED DURING: petal differentiation and expansion stage, E expanded cotyledon stage; CONTAINS InterPro DOMAIN/s: Porin, eukaryotic type (InterPro:IPR001925); BEST Arabidopsis thaliana protein match is: voltage dependent anion channel 2 (TAIR:AT5G67500.1); Has 294 Blast hits to 290 proteins in 43 species: Archae - 0; Bacteria - 0; Metazoa - 5; Fungi - 6; Plants - 279; Viruses - 0; Other Eukaryotes - 4 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    18505481..18507835 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001339445.1 → NP_001319718.1  voltage dependent anion channel 5 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4IZ90

  2. NM_001339446.1 → NP_001325884.1  voltage dependent anion channel 5 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1I9LMK6

  3. NM_114852.1 → NP_190561.1  voltage dependent anion channel 5 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_190561.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9M2W6
    UniProtKB/TrEMBL
    A0A5S9XK89, A0A654FHM7
    Conserved Domains (1) summary
    cd07306
    Location:5 → 225
    Porin3_VDAC; Voltage-dependent anion channel of the outer mitochondrial membrane

  4. NM_001203116.2 → NP_001190045.1  voltage dependent anion channel 5 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001190045.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4IZ90
    Conserved Domains (1) summary
    cl03224
    Location:5 → 82
    Porin3; Eukaryotic porin family that forms channels in the mitochondrial outer membrane
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9M2W6.1

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