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PUR7 purin 7 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 821663, updated on 18-Sep-2024

Summary

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Official Symbol
PUR7
Official Full Name
purin 7
Primary source
TAIR:AT3G21110
Locus tag
AT3G21110
See related
Araport:AT3G21110
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
5'-PHOSPHORIBOSYL-4-(N-SUCCINOCARBOXAMIDE)- 5-AMINOIMIDAZOLE SYNTHETASE; ATPURC; PURC; purin 7; PURIN C; SAIRCAR SYNTHETASE
Summary
5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole synthetase (PUR7, syn. SAICAR synthetase), catalyzes aspartate addition at the alpha-amino group to the growing purine backbone.
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Genomic context

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See PUR7 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
13
Sequence:
Chromosome: 3; NC_003074.8 (7402477..7405674, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ABC transporter-like protein Neighboring gene ABC-2 type transporter family protein Neighboring gene RNA-binding (RRM/RBD/RNP motifs) family protein Neighboring gene F-box and associated interaction domains-containing protein Neighboring gene F-box and associated interaction domains-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. De novo purine synthesis in Arabidopsis thaliana. II. The PUR7 gene encoding 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole synthetase is expressed in rapidly dividing tissues. Senecoff JF, et al. Plant Physiol, 1996 Nov. PMID 8938402, Free PMC Article
  2. AT_CHLORO, a comprehensive chloroplast proteome database with subplastidial localization and curated information on envelope proteins. Ferro M, et al. Mol Cell Proteomics, 2010 Jun. PMID 20061580, Free PMC Article
  3. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
  4. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

NM_001035662.2
NM_001338505.1
NM_113005.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables phosphoribosylaminoimidazolesuccinocarboxamide synthase activity IEA
Inferred from Electronic Annotation
more info
  
enables phosphoribosylaminoimidazolesuccinocarboxamide synthase activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in 'de novo' IMP biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within purine nucleotide biosynthetic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within response to auxin IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast HDA PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in chloroplast stroma HDA PubMed 

General protein information

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Preferred Names
purin 7
NP_001319605.1
  • purin 7 (PUR7); FUNCTIONS IN: phosphoribosylaminoimidazolesuccinocarboxamide synthase activity; INVOLVED IN: response to auxin stimulus, purine nucleotide biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: SAICAR synthetase, conserved site (InterPro:IPR018236), ATP-grasp fold, subdomain 2 (InterPro:IPR013816), SAICAR synthetase (InterPro:IPR001636); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
NP_188748.1
  • purin 7 (PUR7); FUNCTIONS IN: phosphoribosylaminoimidazolesuccinocarboxamide synthase activity; INVOLVED IN: response to auxin stimulus, purine nucleotide biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: SAICAR synthetase, conserved site (InterPro:IPR018236), ATP-grasp fold, subdomain 2 (InterPro:IPR013816), SAICAR synthetase (InterPro:IPR001636); Has 6539 Blast hits to 6539 proteins in 2290 species: Archae - 136; Bacteria - 4333; Metazoa - 76; Fungi - 152; Plants - 62; Viruses - 0; Other Eukaryotes - 1780 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    7402477..7405674 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_113005.4 → NP_188748.1  purin 7 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_188748.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P38025, Q8RXX4, Q9LJC1
    UniProtKB/TrEMBL
    A0A178VEX8, A0A5S9XFR2, A0A654FEK9
    Conserved Domains (1) summary
    PLN02544
    Location:32 → 401
    PLN02544; phosphoribosylaminoimidazole-succinocarboxamide synthase

  2. NM_001338505.1 → NP_001319605.1  purin 7 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P38025, Q8RXX4, Q9LJC1
    UniProtKB/TrEMBL
    A0A178VEX8, A0A5S9XFR2, A0A654FEK9
    Conserved Domains (1) summary
    PLN02544
    Location:32 → 401
    PLN02544; phosphoribosylaminoimidazole-succinocarboxamide synthase

  3. NM_001035662.2 → NP_001030739.1  purin 7 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001030739.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P38025, Q8RXX4, Q9LJC1
    UniProtKB/TrEMBL
    A0A178VEX8, A0A5S9XFR2, A0A654FEK9
    Conserved Domains (1) summary
    PLN02544
    Location:32 → 401
    PLN02544; phosphoribosylaminoimidazole-succinocarboxamide synthase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P38025.2

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