|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02544 |
PLN02544 |
phosphoribosylaminoimidazole-succinocarboxamide synthase |
32-401 |
0e+00 |
|
phosphoribosylaminoimidazole-succinocarboxamide synthase
Pssm-ID: 178159 [Multi-domain] Cd Length: 370 Bit Score: 723.53 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 32 VSFLRAVPEFNKYPKPCSLVMSCQGKAQNQQEERPQLSLDDLVTSNRKGEVLGTIKDSLSNCLSETNLLATVPGLKSRIK 111
Cdd:PLN02544 1 VSSLRTLPEFMKPASPSSGVGGASGKFRAQQLPSPALSLDDLSSSGRRPEVLGAIKEALSNCLTETNLDLTVPGLGSRRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 112 GKVRDIYDAGDYLVLITTDRLSAFDRNLASIPFKGQVLNETSLWWFNNTQHITPNAIVSSPDRNVVIAKKCSVFPIEFVV 191
Cdd:PLN02544 81 GKVRDIYDLGDYLVLVTTDRQSAFDRVLASIPFKGQVLNQTSAWWFNNTKHITPNALVSSPDPNVTIAKKCSVFPVEFVV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 192 RGYVTGSTDTSLWTVYNKGVRNYCGNELSDGLVKNQKLPANILTPTTKAADHDVPISPNEIVEGGFMTQAEFDEASMKAL 271
Cdd:PLN02544 161 RGYMTGSTSTSLWTVYNKGVRNYCGNDLPDGMVKNQKLPANILTPTTKAADHDVPISPEEIVEEGLMTQEDFDEVSSKAL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 272 SLFEFGQGVAKKHGLILVDTKYEFGRSSDGSILLIDEIHTPDSSRYWLAGSYEERFQKGLEPENVDKEFLRLWFKENCNP 351
Cdd:PLN02544 241 ALFAFGQEVAAEHGLILVDTKYEFGKDADGTILLIDEVHTPDSSRYWLADSYEERHAAGLEPENIDKEFLRLWFKENCDP 320
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 1063712857 352 YEDEVLPAAPAELVTELAWRYIFLYETITGSRIDIIPTQEPIHDRISRNT 401
Cdd:PLN02544 321 YKDEVLPEAPAELVCELSWRYIKLYETITGEKFEVPDTQEPIHERISRNV 370
|
|
| PRK12607 |
PRK12607 |
phosphoribosylaminoimidazole-succinocarboxamide synthase; Provisional |
89-407 |
3.19e-163 |
|
phosphoribosylaminoimidazole-succinocarboxamide synthase; Provisional
Pssm-ID: 183621 [Multi-domain] Cd Length: 313 Bit Score: 460.89 E-value: 3.19e-163
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 89 SLSNCLSETNLlatvPGLKSRIKGKVRDIYDAGDY-LVLITTDRLSAFDRNLASIPFKGQVLNETSLWWFNNTQHITPNA 167
Cdd:PRK12607 2 MLPRTLTEFNF----PELPNVYRGKVRDNYDLPDGrRVMVATDRISAFDRVLPAIPYKGQVLNQTAAFWFEATKDICPNH 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 168 IVSSPDRNVVIAKKCSVFPIEFVVRGYVTGSTdtslWTVYNKGVRNYCGNELSDGLVKNQKLPANILTPTTKAAD--HDV 245
Cdd:PRK12607 78 VLAVPDPNVVVGKRCEPFPVEMVVRGYLAGST----WRLYKAGKREMYGVTLPDGLRENQKLPEPIITPTTKAEEggHDE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 246 PISPNEIVEGGFMTQAEFDEASMKALSLFEFGQGVAKKHGLILVDTKYEFGRSSDGSILLIDEIHTPDSSRYWLAGSYEE 325
Cdd:PRK12607 154 PISPEEILAQGLLTPEDWDELSKYALALFARGQEMAAERGLILVDTKYEFGKDADGRIVLIDEIHTPDSSRYWYADGYEE 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 326 RFQKGLEPENVDKEFLRLWFKENCNPYEDEVlPAAPAELVTELAWRYIFLYETITGSRIdIIPTQEPIHDRISRNTSQAL 405
Cdd:PRK12607 234 RFAAGEPQEQLDKEFVRQWLIERCGPYGQEI-PEIPDEVIVSVSERYIELYEKITGETF-VPDSGSPPLARIRKNLAAYL 311
|
..
gi 1063712857 406 SS 407
Cdd:PRK12607 312 AR 313
|
|
| SAICAR_synt_Sc |
cd01414 |
non-metazoan 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; ... |
111-381 |
3.76e-131 |
|
non-metazoan 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Eukaryotic, bacterial, and archaeal group of SAICAR synthetases represented by the Saccharomyces cerevisiae (Sc) enzyme, mostly absent in metazoans. SAICAR synthetase catalyzes the seventh step of the de novo biosynthesis of purine nucleotides (also reported as eighth step). It converts 5-aminoimidazole-4-carboxyribonucleotide (CAIR), ATP, and L-aspartate into 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR), ADP, and phosphate.
Pssm-ID: 133469 [Multi-domain] Cd Length: 279 Bit Score: 378.04 E-value: 3.76e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 111 KGKVRDIYDAGD-YLVLITTDRLSAFDRNLAS-IPFKGQVLNETSLWWFNNTQHITPNAIVSS-------------PDRN 175
Cdd:cd01414 4 SGKVRDVYDLGDgRLLFVATDRISAFDVILPPdIPGKGEVLTQISAFWFELTEDIIPNHLISTdvedlpeikepedPDGR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 176 VVIAKKCSVFPIEFVVRGYVTGSTdtslWTVYNKGVRNyCGNELSDGLVKNQKLPANILTPTTKAA-DHDVPISPNEIVE 254
Cdd:cd01414 84 SMVVKKAKPIPIECIVRGYLTGSG----WKEYQKGGTV-CGIKLPEGLREAQKLPEPIFTPSTKAEeGHDENISFEEAVE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 255 GgfMTQAEFDEASMKALSLFEFGQGVAKKHGLILVDTKYEFGRSSDGSILLIDEIHTPDSSRYWLAGSYEErfqkGLEPE 334
Cdd:cd01414 159 I--IGAELADELRELALALYERAAEYAAKRGLILADTKFEFGLDENGEIILIDEVLTPDSSRFWPADSYEP----GKEQP 232
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 1063712857 335 NVDKEFLRLWFKENCNPYEDEVLPAAPAELVTELAWRYIFLYETITG 381
Cdd:cd01414 233 SFDKQFVRDWLEASGWDKQDPPPPPLPAEVIEKTSARYIEAYERITG 279
|
|
| PurC |
COG0152 |
Phosphoribosylaminoimidazole-succinocarboxamide synthase [Nucleotide transport and metabolism]; ... |
104-383 |
1.15e-91 |
|
Phosphoribosylaminoimidazole-succinocarboxamide synthase [Nucleotide transport and metabolism]; Phosphoribosylaminoimidazole-succinocarboxamide synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439922 Cd Length: 245 Bit Score: 276.19 E-value: 1.15e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 104 PGLKSRIKGKVRDIYDAG-DYLVLITTDRLSAFDRNL-ASIPFKGQVLNETSLWWFNNTQHIT-PNAIVSSPDRNVVIAK 180
Cdd:COG0152 2 PKLELLYEGKVKDVYATDdDTLLMVFKDRISAFDGVKpDPIPGKGEVLNQISAFWFELLEDIGiPTHFIETLSGREMLVK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 181 KCSVFPIEFVVRGYVTGStdtsLWTVYNKGVRnycgneLSDGLVKNQKLPANILTPTTKAAD-HDVPISPNEIVEGGFMT 259
Cdd:COG0152 82 KLEMIPVEVVVRNYAAGS----LWKRYQAGIA------LPLGLEEGTKLPEPIFEPSTKADEgHDPNISEEHIVALGLAT 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 260 QAEFDEASMKALSLFEFGQGVAKKHGLILVDTKYEFGRSSDGSILLIDEIhTPDSSRYWLAGSYeERFqkglepenvDKE 339
Cdd:COG0152 152 EEEAEELRELALKINERLSELAAERGIILVDTKLEFGRDADGEIVLADEI-TPDSSRLWDADTY-ESL---------DKD 220
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 1063712857 340 FLRLWfkencnpyedevlpaapaeLVTELAWRYIFLYETITGSR 383
Cdd:COG0152 221 RFRDW-------------------LGGNTSEAYIEVLERLTGEK 245
|
|
| SAICAR_synt |
pfam01259 |
SAICAR synthetase; Also known as Phosphoribosylaminoimidazole-succinocarboxamide synthase. |
111-354 |
1.93e-90 |
|
SAICAR synthetase; Also known as Phosphoribosylaminoimidazole-succinocarboxamide synthase.
Pssm-ID: 460140 Cd Length: 228 Bit Score: 272.70 E-value: 1.93e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 111 KGKVRDIYDAGD--YLVLITTDRLSAFDRNLA-SIPFKGQVLNETSLWWFNNTQ-HITPNAIVSSPDRNVVIAKKCSVFP 186
Cdd:pfam01259 4 EGKVKDVYETDDpdTLLVVAKDRISAFDGVKKgTIPGKGAVNNQISAFWFELLEiAGIPTHFIKSLSGREMLVKKVKIIP 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 187 IEFVVRGYVTGSTDTSLwtvynkgvrnycgnelsDGLVKNQKLPANILTPTTKAAD-HDVPISPNEIVEGGFMTQAEFDE 265
Cdd:pfam01259 84 LEVVVRNYAAGSLGKRL-----------------PGLKEGTKLPEPIFEPSTKADAlGDPNINEEHIVALGLATEEEAEE 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 266 ASMKALSLFEFGQGVAKKHGLILVDTKYEFGRSSDGSILLIDEIhTPDSSRYWLAGSYEErfqkglEPENVDKEFLRLWF 345
Cdd:pfam01259 147 IRELALKINEILKEYAAERGIILVDTKLEFGLDSDGEIVLADEI-TPDSSRFWDADTYEK------SQESLDKDRFRDDL 219
|
....*....
gi 1063712857 346 KENCNPYED 354
Cdd:pfam01259 220 GDVEEAYQE 228
|
|
| PRK13961 |
PRK13961 |
phosphoribosylaminoimidazole-succinocarboxamide synthase; Provisional |
95-385 |
6.25e-78 |
|
phosphoribosylaminoimidazole-succinocarboxamide synthase; Provisional
Pssm-ID: 237571 Cd Length: 296 Bit Score: 242.80 E-value: 6.25e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 95 SETNLLATVPGLKSRIKGKVRDIYDA-GDYLVLITTDRLSAFDRNLAS-IPFKGQVLNETSLWWFNNTQHITPNAIVSSP 172
Cdd:PRK13961 1 MSTLMESDLPSLPLLGRGKVRDIYAVdDDRLLMVATDRISAFDVILPEpIPDKGRVLTQMSNFWFDKLAHIVPNHLTGID 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 173 DRNV-------------VIAKKCSVFPIEFVVRGYVTGSTdtslWTVYNKGvRNYCGNELSDGLVKNQKLPANILTPTTK 239
Cdd:PRK13961 81 VDDVvpadeadqvlgraVVVKKLKPLPVECVVRGYLTGSG----WKDYQAT-GTVCGIKLPAGLVEASKLPEPIFTPATK 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 240 AA--DHDVPISPNEIVEggfMTQAE-FDEASMKALSLFEFGQGVAKKHGLILVDTKYEFGRSSDGSILLIDEIHTPDSSR 316
Cdd:PRK13961 156 AElgDHDENISFEEVVE---LVGAElAAQLRDATLAIYKEAADYAATRGIIIADTKFEFGLDEDGTLTLMDEVLTPDSSR 232
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1063712857 317 YWLAGSYEErfqkGLEPENVDKEFLRLWFkENCNPYEDEVLPAAPAELVTELAWRYIFLYETITGSRID 385
Cdd:PRK13961 233 FWPADSYQP----GTSQPSFDKQFVRDWL-ETSGWDKTAPAPPLPADVIEKTRAKYREALERLTGKSLD 296
|
|
| purC |
TIGR00081 |
phosphoribosylaminoimidazole-succinocarboxamide synthase; Alternate name: SAICAR synthetase ... |
112-332 |
1.53e-36 |
|
phosphoribosylaminoimidazole-succinocarboxamide synthase; Alternate name: SAICAR synthetase purine de novo biosynthesis. E.coli example noted as homotrimer. Check length. Longer versions may be multifunctional enzymes. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272897 Cd Length: 237 Bit Score: 133.29 E-value: 1.53e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 112 GKVRDIY--DAGDYLVLITTDRLSAFDRNL-ASIPFKGQVLNETSLWWFNNTQHI-TPNAIVSSPDRNVVIAKKCSVFPI 187
Cdd:TIGR00081 12 GKAKDIYetDDPDLLRFVFRDDISAFDGEKkDQIPGKGRLNTKISAFIFEKLEEAgIPTHYIDLIEDREMLVKKLDIIPL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 188 EFVVRGYVTGStdtslwtvynkGVRNYcgnELSDGLVKNQKLPANILTPTtKAADHDVPISPneIVEGGFMTQAEFDEAS 267
Cdd:TIGR00081 92 EVIVRNIAAGS-----------LLKRL---GIPEGLELEQPLVEFIFKPD-EVGDPMLNESY--AEALGLATEEELERIK 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1063712857 268 MKALSLFEFGQGVAKKHGLILVDTKYEFGRSSDGSILLIDEIhTPDSSRYWLAGSYE--------ERFQKGLE 332
Cdd:TIGR00081 155 ELALKVNEVLKKYFDEKGIILVDFKLEFGLDEEGNLILADEV-SPDTCRLWDKETYEvgapkldkDIFRRTLG 226
|
|
| PRK13960 |
PRK13960 |
phosphoribosylaminoimidazole-succinocarboxamide synthase; Provisional |
125-393 |
3.30e-34 |
|
phosphoribosylaminoimidazole-succinocarboxamide synthase; Provisional
Pssm-ID: 184420 Cd Length: 367 Bit Score: 130.59 E-value: 3.30e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 125 VLITTDRLSAFD------RNLASIPFKGQVLNETSLWWFN--NTQHITPNAIVSSPDRNVVIAKKCSVFPIEFVVRGYVT 196
Cdd:PRK13960 57 IMVISDRISAFDciwhgeGGLNGVPGKGAALNAISNHWFKlfKENGLADSHILDIPHPFVWIVQKARPVMIEAICRQYIT 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 197 GStdtsLWTVYNKGVRNYCGNELSDGLVKNQKLPANILTPTTK----------AADhDVPISPNEIvEGGFmtqAEFDEA 266
Cdd:PRK13960 137 GS----MWRAYSKGEREFCGITLPEGLEKDQKLPELLITPSTKgiltgipgvpEAD-DVNISRSDI-EANY---QAFNFS 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 267 SMKALSLFE------FG--QGVAKKHGLILVDTKYEFGRSSDGS----ILLIDEIHTPDSSRYWLAGSYeerfQKGLEPE 334
Cdd:PRK13960 208 SADDIDLYEkllkegFKviSDALAKLDQIFVDTKFEFGYVTDAAgnekLIYMDEVGTPDSSRIWDGAAY----RDGKIVE 283
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1063712857 335 NvDKEFLRLWFKeNCNPYEDEVLP--------------AAPAELVTELAWRYIFLYETITGSRIDII--PTQEPI 393
Cdd:PRK13960 284 N-SKEGFRQFLL-NHFPDPDILLNkdrmperealardnALPLEAMMDVSRTYTGIAEKITGAKIVLSanPKAEII 356
|
|
| SAICAR_synt |
cd00476 |
5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; SAICAR synthetase ... |
111-332 |
1.31e-31 |
|
5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; SAICAR synthetase (the PurC gene product) catalyzes the seventh step of the de novo biosynthesis of purine nucleotides (also reported as eighth step). It converts 5-aminoimidazole-4-carboxyribonucleotide (CAIR), ATP, and L-aspartate into 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR), ADP, and phosphate.
Pssm-ID: 133468 Cd Length: 230 Bit Score: 119.88 E-value: 1.31e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 111 KGKVRDIYDAGD-YLVLITTDRLSAFDRNL-ASIPFKGQVLNETSLWWFNNTQHI-TPNAIVSSPDRNVVIAKKCSVFPI 187
Cdd:cd00476 4 RGKTKIVYETKDgVLLLEFKDDISAGDGARrNFLDEKGDITAKLTLFIFKYLSEAgIPTHFVERLGPRTLLVDKLK*IPL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 188 EFVVRGYVTGSTdtslwtvynkgVRNYCGNElsdglvKNQKLPANILTPTTKA-ADHDVPISPNEIVEGGFMTQAEFDEA 266
Cdd:cd00476 84 EVVVRNRATGSF-----------VKRYGGFK------EGREFPPPLVEFFYKDdAEHDPIVSEDQLERLGFIGKVDVER* 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1063712857 267 SMKALSLFEFGQGVAKKHGLILVDTKYEFGRSSDGSILLIDEIhTPDSSRYWLAGSYE-----ERFQKGLE 332
Cdd:cd00476 147 KELAVKINTVLKKLFSPAGLELWDFKLEFGLDEEGEIVLGDEI-SPDSSRLWRKGGEPydkdlFRRRASLG 216
|
|
| SAICAR_synt_PurC |
cd01415 |
bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) ... |
112-331 |
1.26e-23 |
|
bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; A subfamily of SAICAR synthetases represented by the Thermotoga maritima (Tm) enzyme and E. coli PurC. SAICAR synthetase catalyzes the seventh step of the de novo biosynthesis of purine nucleotides (also reported as eighth step). It converts 5-aminoimidazole-4-carboxyribonucleotide (CAIR), ATP, and L-aspartate into 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR), ADP, and phosphate.
Pssm-ID: 133470 Cd Length: 230 Bit Score: 98.29 E-value: 1.26e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 112 GKVRDIYDAGDYLVLITT--DRLSAFD-RNLASIPFKGQVLNETSLWWFNN-TQHITPNAIVSSPDRNVVIAKKCSVFPI 187
Cdd:cd01415 5 GKAKIVYATDDPDVLIVEfkDDATAFNgKKKDTIEGKGVLNNEISALIFKYlEENGIKTHFIEKLSDREQLVKKVEIIPL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 188 EFVVRGYVTGSTdtslwtvynkgVRNYcgnelsdGLVKNQKLPANILTPTTKAADHDVP-ISPNEIVEGGFMTQAEFDEA 266
Cdd:cd01415 85 EVVVRNIAAGSL-----------VKRL-------GIEEGTVLDPPIVEFYYKNDELGDPlINEDHILALGLATEEELKEI 146
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1063712857 267 SMKALSLFEFGQGVAKKHGLILVDTKYEFGRSSDGSILLIDEIhTPDSSRYWLAGSYE----ERFQKGL 331
Cdd:cd01415 147 KELALKINEVLSEFFAEIGIILVDFKLEFGRDKDGEIVLADEI-SPDTCRLWDKETGEkldkDRFRRDL 214
|
|
| PRK09362 |
PRK09362 |
phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed |
112-331 |
1.88e-20 |
|
phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed
Pssm-ID: 181800 Cd Length: 238 Bit Score: 89.40 E-value: 1.88e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 112 GKVRDIYDAGDYLVLIT--TDRLSAFD---RnlASIPFKGQVLNETSLWWFN--NTQHItPNAIVSSPDRNVVIAKKCSV 184
Cdd:PRK09362 10 GKAKIVYSTDDPDLLIVefKDDATAFNgekK--EQIDGKGVLNNQISSFIFKklEEAGI-PTHFIEKLSDREQLVKKVEI 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 185 FPIEFVVRGYVTGSTdtslwtvynkgVRNYcgnelsdGLVKNQKLPANILTPTTKAADHDVP-ISPNEIVEGGFMTQAEF 263
Cdd:PRK09362 87 IPLEVVVRNVAAGSL-----------VKRL-------GIEEGTVLPPPIVEFYYKNDALGDPmINEDHILALGWATPEEL 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1063712857 264 DEasMKALSL--FEFGQGVAKKHGLILVDTKYEFGRSSDGSILLIDEIhTPDSSRYWLAGSYE----ERFQKGL 331
Cdd:PRK09362 149 AE--IKELALkiNDVLKGLFAGAGIRLVDFKLEFGRDKDGEIVLADEI-SPDTCRLWDKETNEkldkDRFRRDL 219
|
|
| SAICAR_synt_Ade5 |
cd01416 |
Ade5_like 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; ... |
110-342 |
1.21e-15 |
|
Ade5_like 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Eukaryotic group of SAICAR synthetases represented by the Drosophila melanogaster, N-terminal, SAICAR synthetase domain of bifunctional Ade5. The Ade5 gene product (CAIR-SAICARs) catalyzes the sixth and seventh steps of the de novo biosynthesis of purine nucleotides (also reported as seventh and eighth steps). SAICAR synthetase converts 5-aminoimidazole-4-carboxyribonucleotide (CAIR), ATP, and L-aspartate into 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR), ADP, and phosphate.
Pssm-ID: 133471 Cd Length: 252 Bit Score: 76.18 E-value: 1.21e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 110 IKGKVRDIYDAGDY--LVLI-TTDRLSAFDRNLAS-IPFKGQVLNETSLWWFNNTQHI-TPNAIVSSPDRNVVIAKKCSV 184
Cdd:cd01416 8 IEGKTKIVYELPDQpgLVLIqSKDRITAGDGARKDeIEGKAAISNKTTSNVFELLQEAgIKTHFVKQCSPTAFIARKCEM 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 185 FPIEFVVRGYVTGStdtslWTVYNKGVRNycGNELSDGLV----KNQklpaniltpttkaADHDVPISPNEIVEGGFM-- 258
Cdd:cd01416 88 IPIEWVCRRIATGS-----FLKRNPGVKE--GYRFSPPKLeffyKDD-------------ANHDPQWSEEQLLEAKLNcg 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 259 ----TQAEFDEASMKALSLFEFGQGVAKKHGLILVDTKYEFGRSSD-GSILLIDEIHTpDSSRYWLAGsyEERFQKglep 333
Cdd:cd01416 148 glkiGKKEVDIMTKSTIAIFEILEKAWATQDCTLVDMKIEFGVDVTtGEILLADVIDN-DSWRLWPSG--DKRLMK---- 220
|
....*....
gi 1063712857 334 envDKEFLR 342
Cdd:cd01416 221 ---DKQVYR 226
|
|
| PRK13959 |
PRK13959 |
phosphoribosylaminoimidazole-succinocarboxamide synthase; Provisional |
111-399 |
3.72e-12 |
|
phosphoribosylaminoimidazole-succinocarboxamide synthase; Provisional
Pssm-ID: 237570 Cd Length: 341 Bit Score: 67.01 E-value: 3.72e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 111 KGKVRDIYDAGDYL-------VLITTDRLSAFDRNL--ASIPFKGQVLNETSLWWFN---------------NTQHITPN 166
Cdd:PRK13959 1 MGSVKDFYVDEEPTetdlgrgRFVFSDRYSVFDWGImpDEIPDKGASLCTMGAYNFElleeegikthyigvvEDGEVVRL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 167 AIVSSPDRNVVIaKKCSVF------------------------PIEFVVRGYV-TGStdtSLWTvynkgvRNYCGN-ELS 220
Cdd:PRK13959 81 AEASEPPNEMAV-KLTQVPdlpfeggsydydayheaagenyliPLEVIFRNYVpVGS---SLRD------RIKEGKiKPE 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 221 D-GLVKN------QKLPANILTPTTKAADHDVPISPNEIVEGGFMTQAEFDEASMKALSLFEFGQGVAKKHGLILVDTKY 293
Cdd:PRK13959 151 DlGLDADewpeegVKLPEPIVEFSTKYEEQDRYLSRKEADEIAGLSRAEIEELEELALKVDEIITEEAEKRGLIHEDGKI 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063712857 294 EFGRSSDGSILLIDEIHTPDSSRYwlagSYEerfqkGLEpenVDKEFLRLWFK----------------ENCNPYEDEVL 357
Cdd:PRK13959 231 EFALYEEREIRVVDVVGTFDENRF----SYE-----GQE---LSKEVVRQYYRrtewveavkeakeedvADWRSLCEPDP 298
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 1063712857 358 PAAPAELVTELAWRYIFLYETITGSRIDIIPtqePIHDRISR 399
Cdd:PRK13959 299 PPLPDEVVEAVSDLYKAGTNAYTGREWFDAP---PLKDAVDR 337
|
|
|