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Actin-binding FH2 (formin homology 2) family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 818984, updated on 18-Sep-2024

Summary

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Official Full Name
Actin-binding FH2 (formin homology 2) family protein
Primary source
TAIR:AT2G43800
Locus tag
AT2G43800
See related
Araport:AT2G43800
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F18O19.9
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Genomic context

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Location:
chromosome: 2
Exon count:
4
Sequence:
Chromosome: 2; NC_003071.7 (18145439..18149031)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene MAP kinase 6 Neighboring gene corepressor Neighboring gene Small nuclear ribonucleoprotein family protein Neighboring gene UDP-glucosyltransferase 74F2 Neighboring gene miscRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Arabidopsis formin 2 regulates cell-to-cell trafficking by capping and stabilizing actin filaments at plasmodesmata. Diao M, et al. Elife, 2018 Aug 16. PMID 30113309, Free PMC Article
  2. Formin homology 2 domains occur in multiple contexts in angiosperms. Cvrcková F, et al. BMC Genomics, 2004 Jul 15. PMID 15256004, Free PMC Article
  3. Formins: intermediates in signal-transduction cascades that affect cytoskeletal reorganization. Deeks MJ, et al. Trends Plant Sci, 2002 Nov. PMID 12417149
  4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

GeneRIFs: Gene References Into Functions

General gene information

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NM_129942.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables actin binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in actin nucleation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within barbed-end actin filament capping IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within plasmodesmata-mediated intercellular transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
colocalizes_with plasmodesma IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Actin-binding FH2 (formin homology 2) family protein
NP_181908.1
  • Actin-binding FH2 (formin homology 2) family protein; FUNCTIONS IN: actin binding; INVOLVED IN: cellular component organization, actin cytoskeleton organization; LOCATED IN: plasma membrane; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Actin-binding FH2/DRF autoregulatory (InterPro:IPR003104), Actin-binding FH2 (InterPro:IPR015425); BEST Arabidopsis thaliana protein match is: formin homology 1 (TAIR:AT3G25500.1); Has 24262 Blast hits to 14906 proteins in 847 species: Archae - 39; Bacteria - 2066; Metazoa - 8621; Fungi - 3513; Plants - 5949; Viruses - 1021; Other Eukaryotes - 3053 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    18145439..18149031
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_129942.3 → NP_181908.1  Actin-binding FH2 (formin homology 2) family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_181908.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O22824
    UniProtKB/TrEMBL
    A0A178VS83, A0A5S9X7A1
    Conserved Domains (1) summary
    pfam02181
    Location:438 → 839
    FH2; Formin Homology 2 Domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O22824.1

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