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UREG urease accessory protein G [ Arabidopsis thaliana (thale cress) ]

Gene ID: 818010, updated on 18-Sep-2024

Summary

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Official Symbol
UREG
Official Full Name
urease accessory protein G
Primary source
TAIR:AT2G34470
Locus tag
AT2G34470
See related
Araport:AT2G34470
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
PSKF109; T31E10.19; T31E10_19; urease accessory protein G; UREASE ACCESSORY PROTEIN UREG
Summary
Encodes a urease accessory protein which is essential for the activation of plant urease.
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Genomic context

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See UREG in Genome Data Viewer
Location:
chromosome: 2
Exon count:
7
Sequence:
Chromosome: 2; NC_003071.7 (14530735..14532505, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene light-harvesting chlorophyll-protein complex II subunit B1 Neighboring gene HMG-box (high mobility group) DNA-binding family protein Neighboring gene AGAMOUS-like 29 Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein Neighboring gene Ribosomal protein L18ae/LX family protein Neighboring gene cytochrome P450, family 710, subfamily A, polypeptide 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The assembly of the plant urease activation complex and the essential role of the urease accessory protein G (UreG) in delivery of nickel to urease. Myrach T, et al. J Biol Chem, 2017 Sep 1. PMID 28710280, Free PMC Article
  2. Identification of three urease accessory proteins that are required for urease activation in Arabidopsis. Witte CP, et al. Plant Physiol, 2005 Nov. PMID 16244137, Free PMC Article
  3. Glutaredoxin GRXS17 Associates with the Cytosolic Iron-Sulfur Cluster Assembly Pathway. Iñigo S, et al. Plant Physiol, 2016 Oct. PMID 27503603, Free PMC Article
  4. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
  5. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data (including data from studies using transgenic plants or cells from transgenic plants) suggest crucial role for UreG in nickel delivery for urease multimerization/activation. These studies were conducted using recombinant Arabidopsis thaliana proteins expressed in transgenic Nicotiana benthamiana cloned cells or hydroponic plants. (UreG = urease accessory protein UreG)
    Title: The assembly of the plant urease activation complex and the essential role of the urease accessory protein G (UreG) in delivery of nickel to urease.
  2. Plants bearing T-DNA or Ds element insertions in either the structural gene for urease or in any of the three putative urease accessory genes AtureD, AtureF, and AtureG lacked the corresponding mRNAs and were defective in urease activity
    Title: Identification of three urease accessory proteins that are required for urease activation in Arabidopsis.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001036404.1
NM_128999.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
enables nickel cation binding IEA
Inferred from Electronic Annotation
more info
  
enables urease activator activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of catalytic activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
urease accessory protein G
NP_001031481.1
  • urease accessory protein G (UREG); FUNCTIONS IN: nickel ion binding, nucleotide binding, metal ion binding, ATP binding; INVOLVED IN: nitrogen compound metabolic process, positive regulation of metalloenzyme activity; LOCATED IN: membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Urease accessory protein UreG (InterPro:IPR004400), [NiFe]-hydrogenase/urease maturation factor, Ni(2+)-binding GTPase (InterPro:IPR012202), Cobalamin (vitamin B12) biosynthesis CobW-like (InterPro:IPR003495); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
NP_180994.1
  • urease accessory protein G (UREG); FUNCTIONS IN: nickel ion binding, nucleotide binding, metal ion binding, ATP binding; INVOLVED IN: nitrogen compound metabolic process, positive regulation of metalloenzyme activity; LOCATED IN: membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Urease accessory protein UreG (InterPro:IPR004400), [NiFe]-hydrogenase/urease maturation factor, Ni(2+)-binding GTPase (InterPro:IPR012202), Cobalamin (vitamin B12) biosynthesis CobW-like (InterPro:IPR003495); Has 3841 Blast hits to 3838 proteins in 1211 species: Archae - 152; Bacteria - 2767; Metazoa - 198; Fungi - 88; Plants - 54; Viruses - 3; Other Eukaryotes - 579 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    14530735..14532505 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_128999.3 → NP_180994.1  urease accessory protein G [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_180994.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O64700, Q9SYT8
    UniProtKB/TrEMBL
    A0A178VVU4, A0A5S9X3W3
    Conserved Domains (1) summary
    cd05540
    Location:74 → 263
    UreG; urease accessory protein UreG

  2. NM_001036404.1 → NP_001031481.1  urease accessory protein G [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001031481.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4IHW4
    Conserved Domains (1) summary
    cl21455
    Location:77 → 265
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O64700.1

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