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sona SON DNA and RNA binding protein a [ Danio rerio (zebrafish) ]

Gene ID: 792544, updated on 9-Dec-2024

Summary

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Official Symbol
sonaprovided by ZNC
Official Full Name
SON DNA and RNA binding protein aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-5845
See related
Ensembl:ENSDARG00000055389 AllianceGenome:ZFIN:ZDB-GENE-030131-5845
Gene type
protein coding
RefSeq status
PREDICTED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fc30f01; fi20h07; wu:fc30f01; wu:fi20h07; si:dkey-67c22.2
Summary
Predicted to enable RNA binding activity. Predicted to be involved in regulation of mRNA splicing, via spliceosome. Predicted to act upstream of or within regulation of RNA splicing and regulation of cell cycle. Human ortholog(s) of this gene implicated in ZTTK syndrome and congenital anomalies of kidney and urinary tract syndrome with or without hearing loss, abnormal ears, or developmental delay. Orthologous to human SON (SON DNA and RNA binding protein). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See sona in Genome Data Viewer
Location:
chromosome: 9
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (35832294..35842375)
105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (36023109..36033190)

Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene neural cell adhesion molecule 2 Neighboring gene zona pellucida glycoprotein 2, like 1 Neighboring gene regulator of calcineurin 1a Neighboring gene DnaJ (Hsp40) homolog, subfamily C, member 28

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Functional characterization of Atlantic salmon (Salmo salar L.) PepT2 transporters. Vacca F, et al. J Physiol, 2022 May. PMID 35413133, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of RNA splicing IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of cell cycle IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC792544

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001130400.1 → NP_001123872.1  uncharacterized protein LOC792544

    See identical proteins and their annotated locations for NP_001123872.1

    Status: PREDICTED

    Source sequence(s)
    CR548635
    UniProtKB/TrEMBL
    A0A8N7UZ56, B0UYQ8
    Related
    ENSDARP00000106482.2, ENSDART00000130549.4
    Conserved Domains (2) summary
    cl25574
    Location:539 → 744
    TOP2c; TopoisomeraseII
    cl25887
    Location:704 → 815
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007120.7 Reference GRCz11 Primary Assembly

    Range
    35832294..35842375
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021478776.2 → XP_021334451.1  uncharacterized protein LOC792544 isoform X1

    UniProtKB/TrEMBL
    A0A8N7UZ56, B0UYQ8
    Conserved Domains (2) summary
    cl25574
    Location:539 → 744
    TOP2c; TopoisomeraseII
    cl25887
    Location:704 → 815
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394761.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    189907..200065
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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