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Conserved domains on  [gi|1207185128|ref|XP_021334451|]
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uncharacterized protein [Danio rerio]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PTZ00108 super family cl36510
DNA topoisomerase 2-like protein; Provisional
539-744 8.18e-07

DNA topoisomerase 2-like protein; Provisional


The actual alignment was detected with superfamily member PTZ00108:

Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 53.51  E-value: 8.18e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207185128  539 RKTKKQKSKLSRSISPKRKSRSISREQQSSDRSISPSMKAHSPSPAKEDKSLKDKNSKETSETTQKLLVAIEEKFEVKGT 618
Cdd:PTZ00108  1157 RLKSKTKGKASKLRKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSGSDQEDDEEQKTKPK 1236
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207185128  619 AGSGGWRPVTTECTSVQKPKNEDVTSECGPLSAKVKEEPEDPSKCEERPIRSRSLSLDPVPQHGTAGSEEDYQSGSSRSP 698
Cdd:PTZ00108  1237 KSSVKRLKSKKNNSSKSSEDNDEFSSDDLSKEGKPKNAPKRVSAVQYSPPPPSKRPDGESNGGSKPSSPTKKKVKKRLEG 1316
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 1207185128  699 SPITKEDSKSSNKTSPVRKKrsrSTSSTKKRRSKSKSVSNKRRSRS 744
Cdd:PTZ00108  1317 SLAALKKKKKSEKKTARKKK---SKTRVKQASASQSSRLLRRPRKK 1359
RSRP super family cl26279
Arginine/Serine-Rich protein 1; RSRP1 is an eukaryotic protein family. Its function is unknown.
703-814 2.84e-04

Arginine/Serine-Rich protein 1; RSRP1 is an eukaryotic protein family. Its function is unknown.


The actual alignment was detected with superfamily member pfam17069:

Pssm-ID: 293674 [Multi-domain]  Cd Length: 299  Bit Score: 44.00  E-value: 2.84e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207185128  703 KEDSKSSNKTSPVRKKRSRSTSSTKKRRSKSKSvSNKRRSRSPARKRKSRSPSHSRKRRTKSRSPVRKRRSRSRSTNRRA 782
Cdd:pfam17069   17 KSPSTSSSGSSSRLSSRSRSRSSSRSSRSHSRS-SSRFSSRSRSRPRRSRSRSRSRRRHQRKYRRYSRSYSRSRSRSRRR 95
                           90       100       110
                   ....*....|....*....|....*....|..
gi 1207185128  783 KSRSKSHTRTKRSKSKSPKRKRSKSRSPVRKR 814
Cdd:pfam17069   96 RYYRRSRYRYSRRYYRSPSRSRSRSRSRSRGR 127
 
Name Accession Description Interval E-value
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
539-744 8.18e-07

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 53.51  E-value: 8.18e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207185128  539 RKTKKQKSKLSRSISPKRKSRSISREQQSSDRSISPSMKAHSPSPAKEDKSLKDKNSKETSETTQKLLVAIEEKFEVKGT 618
Cdd:PTZ00108  1157 RLKSKTKGKASKLRKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSGSDQEDDEEQKTKPK 1236
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207185128  619 AGSGGWRPVTTECTSVQKPKNEDVTSECGPLSAKVKEEPEDPSKCEERPIRSRSLSLDPVPQHGTAGSEEDYQSGSSRSP 698
Cdd:PTZ00108  1237 KSSVKRLKSKKNNSSKSSEDNDEFSSDDLSKEGKPKNAPKRVSAVQYSPPPPSKRPDGESNGGSKPSSPTKKKVKKRLEG 1316
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 1207185128  699 SPITKEDSKSSNKTSPVRKKrsrSTSSTKKRRSKSKSVSNKRRSRS 744
Cdd:PTZ00108  1317 SLAALKKKKKSEKKTARKKK---SKTRVKQASASQSSRLLRRPRKK 1359
RSRP pfam17069
Arginine/Serine-Rich protein 1; RSRP1 is an eukaryotic protein family. Its function is unknown.
703-814 2.84e-04

Arginine/Serine-Rich protein 1; RSRP1 is an eukaryotic protein family. Its function is unknown.


Pssm-ID: 293674 [Multi-domain]  Cd Length: 299  Bit Score: 44.00  E-value: 2.84e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207185128  703 KEDSKSSNKTSPVRKKRSRSTSSTKKRRSKSKSvSNKRRSRSPARKRKSRSPSHSRKRRTKSRSPVRKRRSRSRSTNRRA 782
Cdd:pfam17069   17 KSPSTSSSGSSSRLSSRSRSRSSSRSSRSHSRS-SSRFSSRSRSRPRRSRSRSRSRRRHQRKYRRYSRSYSRSRSRSRRR 95
                           90       100       110
                   ....*....|....*....|....*....|..
gi 1207185128  783 KSRSKSHTRTKRSKSKSPKRKRSKSRSPVRKR 814
Cdd:pfam17069   96 RYYRRSRYRYSRRYYRSPSRSRSRSRSRSRGR 127
U2AF_lg TIGR01642
U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of ...
704-815 2.78e-03

U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of an N-terminal arginine-rich low complexity domain followed by three tandem RNA recognition motifs (pfam00076). The well-characterized members of this family are auxilliary components of the U2 small nuclear ribonuclearprotein splicing factor (U2AF). These proteins are closely related to the CC1-like subfamily of splicing factors (TIGR01622). Members of this subfamily are found in plants, metazoa and fungi.


Pssm-ID: 273727 [Multi-domain]  Cd Length: 509  Bit Score: 41.42  E-value: 2.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207185128  704 EDSKSSNKTSPVRKKRSRSTSSTKKRRSKSKSVSNKRRSRSPARKRKSRSPSHSRKRRTKSRSPVRKRRSrsrstnrraK 783
Cdd:TIGR01642    3 EEPDREREKSRGRDRDRSSERPRRRSRDRSRFRDRHRRSRERSYREDSRPRDRRRYDSRSPRSLRYSSVR---------R 73
                           90       100       110
                   ....*....|....*....|....*....|..
gi 1207185128  784 SRSKSHTRTKRSKSKSPKRKRSKSRSPVRKRR 815
Cdd:TIGR01642   74 SRDRPRRRSRSVRSIEQHRRRLRDRSPSNQWR 105
 
Name Accession Description Interval E-value
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
539-744 8.18e-07

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 53.51  E-value: 8.18e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207185128  539 RKTKKQKSKLSRSISPKRKSRSISREQQSSDRSISPSMKAHSPSPAKEDKSLKDKNSKETSETTQKLLVAIEEKFEVKGT 618
Cdd:PTZ00108  1157 RLKSKTKGKASKLRKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSGSDQEDDEEQKTKPK 1236
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207185128  619 AGSGGWRPVTTECTSVQKPKNEDVTSECGPLSAKVKEEPEDPSKCEERPIRSRSLSLDPVPQHGTAGSEEDYQSGSSRSP 698
Cdd:PTZ00108  1237 KSSVKRLKSKKNNSSKSSEDNDEFSSDDLSKEGKPKNAPKRVSAVQYSPPPPSKRPDGESNGGSKPSSPTKKKVKKRLEG 1316
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 1207185128  699 SPITKEDSKSSNKTSPVRKKrsrSTSSTKKRRSKSKSVSNKRRSRS 744
Cdd:PTZ00108  1317 SLAALKKKKKSEKKTARKKK---SKTRVKQASASQSSRLLRRPRKK 1359
RSRP pfam17069
Arginine/Serine-Rich protein 1; RSRP1 is an eukaryotic protein family. Its function is unknown.
703-814 2.84e-04

Arginine/Serine-Rich protein 1; RSRP1 is an eukaryotic protein family. Its function is unknown.


Pssm-ID: 293674 [Multi-domain]  Cd Length: 299  Bit Score: 44.00  E-value: 2.84e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207185128  703 KEDSKSSNKTSPVRKKRSRSTSSTKKRRSKSKSvSNKRRSRSPARKRKSRSPSHSRKRRTKSRSPVRKRRSRSRSTNRRA 782
Cdd:pfam17069   17 KSPSTSSSGSSSRLSSRSRSRSSSRSSRSHSRS-SSRFSSRSRSRPRRSRSRSRSRRRHQRKYRRYSRSYSRSRSRSRRR 95
                           90       100       110
                   ....*....|....*....|....*....|..
gi 1207185128  783 KSRSKSHTRTKRSKSKSPKRKRSKSRSPVRKR 814
Cdd:pfam17069   96 RYYRRSRYRYSRRYYRSPSRSRSRSRSRSRGR 127
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
537-763 4.94e-04

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 44.27  E-value: 4.94e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207185128  537 KLRKT-KKQKSKLSRSISPKRKSRSISREQQSSDRSISPSMKAHSPSPAKEDKSLKDKNSKETSETTQKLLVAIEEKFEV 615
Cdd:PTZ00108  1136 KFEEAlEEQEEVEEKEIAKEQRLKSKTKGKASKLRKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDN 1215
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207185128  616 KGTAGSGgwrpvttectsvqKPKNEDVTSECGPLSAKVKEEPEDPSKCEERPIRSRSLSLDPVPQHGTAGSEEDYQSGSS 695
Cdd:PTZ00108  1216 KKSNSSG-------------SDQEDDEEQKTKPKKSSVKRLKSKKNNSSKSSEDNDEFSSDDLSKEGKPKNAPKRVSAVQ 1282
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1207185128  696 RSPSPITKEDSKSSNKTSpvrkKRSRSTSSTKKRRSKSKSV--SNKRRSR-SPARKRKSR--------SPSHSRKRRTK 763
Cdd:PTZ00108  1283 YSPPPPSKRPDGESNGGS----KPSSPTKKKVKKRLEGSLAalKKKKKSEkKTARKKKSKtrvkqasaSQSSRLLRRPR 1357
U2AF_lg TIGR01642
U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of ...
704-815 2.78e-03

U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of an N-terminal arginine-rich low complexity domain followed by three tandem RNA recognition motifs (pfam00076). The well-characterized members of this family are auxilliary components of the U2 small nuclear ribonuclearprotein splicing factor (U2AF). These proteins are closely related to the CC1-like subfamily of splicing factors (TIGR01622). Members of this subfamily are found in plants, metazoa and fungi.


Pssm-ID: 273727 [Multi-domain]  Cd Length: 509  Bit Score: 41.42  E-value: 2.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207185128  704 EDSKSSNKTSPVRKKRSRSTSSTKKRRSKSKSVSNKRRSRSPARKRKSRSPSHSRKRRTKSRSPVRKRRSrsrstnrraK 783
Cdd:TIGR01642    3 EEPDREREKSRGRDRDRSSERPRRRSRDRSRFRDRHRRSRERSYREDSRPRDRRRYDSRSPRSLRYSSVR---------R 73
                           90       100       110
                   ....*....|....*....|....*....|..
gi 1207185128  784 SRSKSHTRTKRSKSKSPKRKRSKSRSPVRKRR 815
Cdd:TIGR01642   74 SRDRPRRRSRSVRSIEQHRRRLRDRSPSNQWR 105
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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