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PAM peptidylglycine alpha-amidating monooxygenase [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 707733, updated on 17-Aug-2024

Summary

Official Symbol
PAMprovided by VGNC
Official Full Name
peptidylglycine alpha-amidating monooxygenaseprovided by VGNC
Primary source
VGNC:VGNC:75752
See related
Ensembl:ENSMMUG00000007844
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
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Genomic context

See PAM in Genome Data Viewer
Location:
chromosome: 6
Exon count:
29
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (100139802..100418216)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (100026104..100306786)

Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene solute carrier organic anion transporter family member 4C1 Neighboring gene uncharacterized LOC106998873 Neighboring gene solute carrier organic anion transporter family member 6A1 Neighboring gene eukaryotic translation initiation factor 3 subunit K pseudogene Neighboring gene diphosphoinositol pentakisphosphate kinase 2 Neighboring gene gypsy retrotransposon integrase 1

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables copper ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables peptidylglycine monooxygenase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in peptide metabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
peptidyl-glycine alpha-amidating monooxygenase
XP_001096156.3
XP_002804508.2
XP_014995981.2
XP_014995982.2
XP_014995983.2
XP_014995984.2
XP_014995985.2
XP_014995986.2
XP_014995987.2
XP_014995988.2
XP_014995989.2
XP_014995990.2
XP_028705442.1
XP_028705443.1
XP_028705444.1
XP_028705445.1
XP_028705446.1
XP_028705447.1
XP_028705448.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041759.1 Reference Mmul_10 Primary Assembly

    Range
    100139802..100418216
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015140495.2XP_014995981.2  peptidyl-glycine alpha-amidating monooxygenase isoform X1

    UniProtKB/TrEMBL
    A0A1D5QQ95, I0FS58
    Conserved Domains (3) summary
    cd14958
    Location:501808
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:60169
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:197343
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain
  2. XM_015140502.2XP_014995988.2  peptidyl-glycine alpha-amidating monooxygenase isoform X9

    UniProtKB/TrEMBL
    G7MVI0
    Conserved Domains (3) summary
    cd14958
    Location:394701
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:60169
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:197343
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain
  3. XM_015140503.2XP_014995989.2  peptidyl-glycine alpha-amidating monooxygenase isoform X10

    UniProtKB/TrEMBL
    A0A5F7ZUP6, G7MVI0
    Related
    ENSMMUP00000068359.1, ENSMMUT00000080675.1
    Conserved Domains (3) summary
    cd14958
    Location:394701
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:60169
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:197343
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain
  4. XM_015140504.2XP_014995990.2  peptidyl-glycine alpha-amidating monooxygenase isoform X13

    UniProtKB/TrEMBL
    A0A5F7ZP68, G7MVI0
    Related
    ENSMMUP00000067441.1, ENSMMUT00000095056.1
    Conserved Domains (3) summary
    cd14958
    Location:394701
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:60169
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:197343
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain
  5. XM_028849612.1XP_028705445.1  peptidyl-glycine alpha-amidating monooxygenase isoform X11

    UniProtKB/TrEMBL
    G7MVI0
    Conserved Domains (3) summary
    cd14958
    Location:394701
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:60169
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:197343
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain
  6. XM_028849613.1XP_028705446.1  peptidyl-glycine alpha-amidating monooxygenase isoform X12

    UniProtKB/TrEMBL
    G7MVI0
    Conserved Domains (3) summary
    cd14958
    Location:394701
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:60169
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:197343
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain
  7. XM_028849614.1XP_028705447.1  peptidyl-glycine alpha-amidating monooxygenase isoform X14

    UniProtKB/TrEMBL
    H9FV29, I2CT68
    Conserved Domains (3) summary
    cd14958
    Location:394701
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:60169
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:197343
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain
  8. XM_002804462.3XP_002804508.2  peptidyl-glycine alpha-amidating monooxygenase isoform X15

    UniProtKB/TrEMBL
    I2CT68
    Conserved Domains (3) summary
    cd14958
    Location:394701
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:60169
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:197343
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain
  9. XM_028849615.1XP_028705448.1  peptidyl-glycine alpha-amidating monooxygenase isoform X16

    UniProtKB/TrEMBL
    H9FV29
    Conserved Domains (3) summary
    cd14958
    Location:394701
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:60169
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:197343
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain
  10. XM_015140497.2XP_014995983.2  peptidyl-glycine alpha-amidating monooxygenase isoform X2

    UniProtKB/TrEMBL
    A0A1D5QQ95, I2CX43
    Conserved Domains (3) summary
    cd14958
    Location:501808
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:60169
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:197343
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain
  11. XM_015140500.2XP_014995986.2  peptidyl-glycine alpha-amidating monooxygenase isoform X5

    UniProtKB/TrEMBL
    A0A1D5QQ95, F7BDY1
    Related
    ENSMMUP00000010304.4, ENSMMUT00000010987.4
    Conserved Domains (3) summary
    cd14958
    Location:501808
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:60169
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:197343
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain
  12. XM_015140498.2XP_014995984.2  peptidyl-glycine alpha-amidating monooxygenase isoform X3

    UniProtKB/TrEMBL
    A0A1D5QQ95
    Conserved Domains (3) summary
    cd14958
    Location:501808
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:60169
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:197343
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain
  13. XM_015140499.2XP_014995985.2  peptidyl-glycine alpha-amidating monooxygenase isoform X4

    UniProtKB/TrEMBL
    A0A1D5QQ95
    Conserved Domains (3) summary
    cd14958
    Location:501808
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:60169
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:197343
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain
  14. XM_001096156.4XP_001096156.3  peptidyl-glycine alpha-amidating monooxygenase isoform X6

    UniProtKB/TrEMBL
    H9FV29, I2CT68
    Related
    ENSMMUP00000010306.4, ENSMMUT00000010989.4
    Conserved Domains (3) summary
    cd14958
    Location:501808
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:60169
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:197343
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain
  15. XM_015140501.2XP_014995987.2  peptidyl-glycine alpha-amidating monooxygenase isoform X7

    UniProtKB/TrEMBL
    I2CT68
    Conserved Domains (3) summary
    cd14958
    Location:501808
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:60169
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:197343
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain
  16. XM_028849611.1XP_028705444.1  peptidyl-glycine alpha-amidating monooxygenase isoform X8

    UniProtKB/TrEMBL
    F7BDX3, H9FV29
    Related
    ENSMMUP00000010305.4, ENSMMUT00000010988.4
    Conserved Domains (3) summary
    cd14958
    Location:501808
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:60169
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:197343
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain
  17. XM_015140496.2XP_014995982.2  peptidyl-glycine alpha-amidating monooxygenase isoform X1

    UniProtKB/TrEMBL
    A0A1D5QQ95, I0FS58
    Conserved Domains (3) summary
    cd14958
    Location:501808
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:60169
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:197343
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain
  18. XM_028849609.1XP_028705442.1  peptidyl-glycine alpha-amidating monooxygenase isoform X1

    UniProtKB/TrEMBL
    A0A1D5QQ95, I0FS58
    Conserved Domains (3) summary
    cd14958
    Location:501808
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:60169
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:197343
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain
  19. XM_028849610.1XP_028705443.1  peptidyl-glycine alpha-amidating monooxygenase isoform X1

    UniProtKB/TrEMBL
    A0A1D5QQ95, I0FS58
    Related
    ENSMMUP00000071213.1, ENSMMUT00000088391.1
    Conserved Domains (3) summary
    cd14958
    Location:501808
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:60169
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:197343
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain