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Commd2 COMM domain containing 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 688478, updated on 27-Nov-2024

Summary

Official Symbol
Commd2provided by RGD
Official Full Name
COMM domain containing 2provided by RGD
Primary source
RGD:1588810
See related
EnsemblRapid:ENSRNOG00000043386 AllianceGenome:RGD:1588810
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Orthologous to human COMMD2 (COMM domain containing 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Lung (RPKM 63.0), Adrenal (RPKM 58.6) and 9 other tissues See more
Orthologs
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Genomic context

See Commd2 in Genome Data Viewer
Location:
2q26
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (143998672..144002918, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (141848661..141852907, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (147774767..147779013, complement)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene transmembrane 4 L six family member 4 Neighboring gene WW domain containing transcription regulator 1 Neighboring gene ribosomal protein L12, pseudogene 2 Neighboring gene uncharacterized LOC108350015 Neighboring gene ribosomal protein L36A, pseudogene 1 Neighboring gene ankyrin repeat and ubiquitin domain containing 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General protein information

Preferred Names
COMM domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109503.1NP_001102973.1  COMM domain-containing protein 2

    See identical proteins and their annotated locations for NP_001102973.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474003
    UniProtKB/TrEMBL
    A6JVG6, A6JVG7, D3ZLN7
    Related
    ENSRNOP00000022778.5, ENSRNOT00000022778.7
    Conserved Domains (1) summary
    cd04750
    Location:26190
    Commd2; COMM_Domain containing protein 2. The COMM Domain is found at the C-terminus of a variety of proteins; presumably all COMM_Domain containing proteins are located in the nucleus and the COMM domain plays a role in protein-protein interactions. Several ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    143998672..144002918 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063282564.1XP_063138634.1  COMM domain-containing protein 2 isoform X1

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001106435.1: Suppressed sequence

    Description
    NM_001106435.1: This RefSeq was temporarily suppressed because currently there is not sufficient data to support this transcript.