U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

C27H6.9 Mitochondrial genome maintenance exonuclease 1 [ Caenorhabditis elegans ]

Gene ID: 6418702, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
C27H6.9
Official Full Name
Mitochondrial genome maintenance exonuclease 1
Primary source
WormBase:WBGene00077500
Locus tag
CELE_C27H6.9
See related
AllianceGenome:WB:WBGene00077500
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable single-stranded DNA exodeoxyribonuclease activity. Predicted to be involved in mitochondrial DNA replication. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 11. Orthologous to human MGME1 (mitochondrial genome maintenance exonuclease 1). [provided by Alliance of Genome Resources, Jan 2025]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See C27H6.9 in Genome Data Viewer
Location:
chromosome: V
Exon count:
4
Sequence:
Chromosome: V; NC_003283.11 (9982868..9983932)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene RuvB-like 1 Neighboring gene Schlafen-like protein 1 Neighboring gene TPR_REGION domain-containing protein Neighboring gene MYG1 protein C27H6.8 Neighboring gene Piwi domain-containing protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables exonuclease activity IEA
Inferred from Electronic Annotation
more info
  
enables single-stranded DNA exodeoxyribonuclease activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables single-stranded DNA exodeoxyribonuclease activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in mitochondrial DNA repair IEA
Inferred from Electronic Annotation
more info
  
involved_in mitochondrial DNA replication IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial genome maintenance IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Mitochondrial genome maintenance exonuclease 1
NP_001122867.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    9982868..9983932
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001129395.2 → NP_001122867.1  Mitochondrial genome maintenance exonuclease 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001122867.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A9QY30
    Conserved Domains (1) summary
    cl00641
    Location:163 → 264
    Cas4_I-A_I-B_I-C_I-D_II-B; CRISPR/Cas system-associated protein Cas4
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools