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megf11 multiple EGF-like-domains 11 [ Danio rerio (zebrafish) ]

Gene ID: 563468, updated on 9-Dec-2024

Summary

Official Symbol
megf11provided by ZNC
Official Full Name
multiple EGF-like-domains 11provided by ZNC
Primary source
ZFIN:ZDB-GENE-060503-252
See related
Ensembl:ENSDARG00000062686 AllianceGenome:ZFIN:ZDB-GENE-060503-252
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkey-242h9.1; si:dkey-261f4.1
Summary
Predicted to enable scavenger receptor activity and zinc ion binding activity. Predicted to be located in membrane. Orthologous to human MEGF11 (multiple EGF like domains 11). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See megf11 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (19142409..19405607, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (19153220..19416516, complement)

Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene si:dkey-242h9.3 Neighboring gene RAB11a, member RAS oncogene family Neighboring gene uncharacterized LOC137488357 Neighboring gene uncharacterized LOC137488272 Neighboring gene uncharacterized LOC137488273 Neighboring gene mitogen-activated protein kinase kinase 1

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables scavenger receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
multiple epidermal growth factor-like domains protein 11

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007129.7 Reference GRCz11 Primary Assembly

    Range
    19142409..19405607 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021467800.2XP_021323475.1  multiple epidermal growth factor-like domains protein 11 isoform X2

    UniProtKB/TrEMBL
    A0A2R8Q0P0, A0A8M9PQS0
    Related
    ENSDARP00000146687.1, ENSDART00000191290.1
    Conserved Domains (1) summary
    pfam07546
    Location:3298
    EMI; EMI domain
  2. XM_009293604.4XP_009291879.1  multiple epidermal growth factor-like domains protein 11 isoform X1

    UniProtKB/TrEMBL
    A0A8M3AKE8, F1Q4V3
    Related
    ENSDARP00000085288.5, ENSDART00000090855.5
    Conserved Domains (1) summary
    pfam07546
    Location:3298
    EMI; EMI domain

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018395020.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    400354..617568 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021473271.2XP_021328946.1  multiple epidermal growth factor-like domains protein 11 isoform X2

    UniProtKB/TrEMBL
    A0A2R8Q0P0, A0A8M9PQS0
    Conserved Domains (1) summary
    pfam07546
    Location:3298
    EMI; EMI domain
  2. XM_021473270.2XP_021328945.1  multiple epidermal growth factor-like domains protein 11 isoform X1

    UniProtKB/TrEMBL
    A0A8M3AKE8, F1Q4V3
    Conserved Domains (1) summary
    pfam07546
    Location:3298
    EMI; EMI domain