idh3g isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: idh3gprovided by ZNC
Official Full Name: isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gammaprovided by ZNC
Primary source: ZFIN:ZDB-GENE-050417-435
See related: Ensembl:ENSDARG00000023648 AllianceGenome:ZFIN:ZDB-GENE-050417-435
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fa01b02; im:7054683; wu:fa01b02; wu:fc88f06; zgc:113076
Summary: Predicted to enable NAD binding activity; magnesium ion binding activity; and oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Predicted to be involved in isocitrate metabolic process and tricarboxylic acid cycle. Predicted to be active in mitochondrion. Orthologous to human IDH3G (isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 23

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	23	NC_007134.7 (25121995..25135107, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	23	NC_007134.6 (25195454..25208566, complement)

Chromosome 23 - NC_007134.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

idh3g (e-PCR)
- UniSTS:205595

fa96e06.y1 (e-PCR)
- UniSTS:189726

fa01b02.s1 (e-PCR)
- UniSTS:202113

fc88f06.x1 (e-PCR)
- UniSTS:188359

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables NAD binding	IEA Inferred from Electronic Annotation more info
enables magnesium ion binding	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in isocitrate metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in tricarboxylic acid cycle	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within tricarboxylic acid cycle	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial

Names: isocitrate dehydrogenase (NAD(+)) 3 gamma; isocitrate dehydrogenase 3 (NAD+) gamma

NP_001230101.1

EC 1.1.1.41

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001243172.1 → NP_001230101.1 isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial

Status: VALIDATED

Source sequence(s)

CR847803, EH448219, EH555117, EH576227

UniProtKB/TrEMBL

A0A8M1P3Y1, F1QZA4

Related

ENSDARP00000094764.4, ENSDART00000103989.5

Conserved Domains (1) summary

TIGR00175
Location:49 → 381

mito_nad_idh; isocitrate dehydrogenase, NAD-dependent, mitochondrial type