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RhoGAP102A Rho GTPase activating protein at 102A [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43781, updated on 4-Jan-2025

Summary

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Official Symbol
RhoGAP102Aprovided by FlyBase
Official Full Name
Rho GTPase activating protein at 102Aprovided by FlyBase
Primary source
FLYBASE:FBgn0259216
Locus tag
Dmel_CG42316
See related
AllianceGenome:FB:FBgn0259216
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BP1050; CG1748; CG34013; CG42316; Dmel\CG42316; Dm_4:1183; mlncRNA102B1; rhoGAP102A
Old locus tag
Dmel_CG1748; Dmel_CG34013
Summary
Predicted to enable GTPase activator activity. Predicted to be involved in signal transduction. Orthologous to human ARHGAP36 (Rho GTPase activating protein 36) and ARHGAP6 (Rho GTPase activating protein 6). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See RhoGAP102A in Genome Data Viewer
Location:
102B1-102B1; 4-0 cM
Exon count:
13
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 4 NC_004353.4 (254997..265574)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 4 NC_004353.3 (275623..286200)

Chromosome 4 - NC_004353.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene defective proboscis extension response 7 Neighboring gene Nuclear factor I Neighboring gene long non-coding RNA:CR44023

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Accelerated homologous recombination and subsequent genome modification in Drosophila. Baena-Lopez LA, et al. Development, 2013 Dec. PMID 24154526, Free PMC Article
  2. The KRÜPPEL-like transcription factor DATILÓGRAFO is required in specific cholinergic neurons for sexual receptivity in Drosophila females. Schinaman JM, et al. PLoS Biol, 2014 Oct. PMID 25291190, Free PMC Article
  3. Effect of spaceflight on the circadian rhythm, lifespan and gene expression of Drosophila melanogaster. Ma L, et al. PLoS One, 2015. PMID 25798821, Free PMC Article
  4. Regulating axon branch stability: the role of p190 RhoGAP in repressing a retraction signaling pathway. Billuart P, et al. Cell, 2001 Oct 19. PMID 11672527
  5. Prepatterning by RhoGEFs governs Rho GTPase spatiotemporal dynamics during wound repair. Nakamura M, et al. J Cell Biol, 2017 Dec 4. PMID 28923977, Free PMC Article

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

mobile_element

  • Loc: 259771-259838 mobile_element_type = transposon:INE-1{}5318
  • Loc: 260948-261036 mobile_element_type = transposon:INE-1{}5319

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables GTPase activator activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
Rho GTPase activating protein at 102A
Names
CG42316-PC
CG42316-PD
CG42316-PE
CG42316-PF
RhoGAP102A-PC
RhoGAP102A-PD
RhoGAP102A-PE
RhoGAP102A-PF

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004353.4 Reference assembly

    Range
    254997..265574
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001258487.3 → NP_001245416.1  Rho GTPase activating protein at 102A, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245416.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H9XVN1
    Conserved Domains (1) summary
    cl02570
    Location:874 → 1069
    RhoGAP; RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when ...

  2. NM_001272121.2 → NP_001259050.1  Rho GTPase activating protein at 102A, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259050.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    L0MPN2
    Conserved Domains (1) summary
    cl02570
    Location:874 → 1069
    RhoGAP; RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when ...

  3. NM_143657.5 → NP_651914.3  Rho GTPase activating protein at 102A, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651914.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9V4C2
    Conserved Domains (1) summary
    cl02570
    Location:874 → 1054
    RhoGAP; RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when ...

  4. NM_001038713.4 → NP_001033802.2  Rho GTPase activating protein at 102A, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001033802.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q2PDM2
    Conserved Domains (1) summary
    cl02570
    Location:874 → 1064
    RhoGAP; RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
H9XVN1 H9XVN1
L0MPN2 L0MPN2
Q2PDM2 Q2PDM2
Q9V4C2 Q9V4C2

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