U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

syn2a synapsin IIa [ Danio rerio (zebrafish) ]

Gene ID: 436870, updated on 9-Dec-2024

Summary

Official Symbol
syn2aprovided by ZNC
Official Full Name
synapsin IIaprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040718-341
See related
Ensembl:ENSDARG00000045945 AllianceGenome:ZFIN:ZDB-GENE-040718-341
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
syn1; syn2; zgc:92311
Summary
Predicted to enable ATP binding activity. Predicted to be involved in synapse organization and synaptic vesicle clustering. Predicted to act upstream of or within neurotransmitter secretion. Predicted to be located in synaptic vesicle. Predicted to be active in synaptic vesicle membrane. Is expressed in DEL; nervous system; spinal cord neural tube; and yolk syncytial layer. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human SYN2 (synapsin II). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See syn2a in Genome Data Viewer
Location:
chromosome: 23
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (4751959..4775446, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (4816374..4839861, complement)

Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene CCHC-type zinc finger, nucleic acid binding protein a Neighboring gene Raf-1 proto-oncogene, serine/threonine kinase a Neighboring gene vestigial-like family member 4a Neighboring gene solute carrier family 6 member 1a

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within neurotransmitter secretion IEA
Inferred from Electronic Annotation
more info
 
involved_in synapse organization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in synaptic vesicle clustering IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in synapse IEA
Inferred from Electronic Annotation
more info
 
located_in synaptic vesicle IEA
Inferred from Electronic Annotation
more info
 
is_active_in synaptic vesicle membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
synapsin-2a
Names
synapsin II
synapsin2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002597.2NP_001002597.2  synapsin-2a

    Status: VALIDATED

    Source sequence(s)
    CU468010
    UniProtKB/TrEMBL
    A0A8M1N0R8, F1R0A8
    Related
    ENSDARP00000067530.4, ENSDART00000067531.5
    Conserved Domains (3) summary
    pfam02078
    Location:102199
    Synapsin; Synapsin, N-terminal domain
    pfam10581
    Location:127
    Synapsin_N; Synapsin N-terminal
    cl17255
    Location:201403
    ATP-grasp_4; ATP-grasp domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007134.7 Reference GRCz11 Primary Assembly

    Range
    4751959..4775446 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)