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Wfdc15a WAP four-disulfide core domain 15A [ Rattus norvegicus (Norway rat) ]

Gene ID: 408226, updated on 9-Dec-2024

Summary

Official Symbol
Wfdc15aprovided by RGD
Official Full Name
WAP four-disulfide core domain 15Aprovided by RGD
Primary source
RGD:1303026
See related
EnsemblRapid:ENSRNOG00000053099 AllianceGenome:RGD:1303026
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Wfdcl1
Summary
Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in antibacterial humoral response and innate immune response. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Dec 2024]
Expression
Restricted expression toward (RPKM 44.0) See more
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Genomic context

See Wfdc15a in Genome Data Viewer
Location:
3q42
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (173292668..173294900, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (152873311..152874619, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (160591512..160591891, complement)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene WAP four-disulfide core domain 5 Neighboring gene uncharacterized LOC108350520 Neighboring gene WAP four-disulfide core domain 12 Neighboring gene WAP four-disulfide core domain 15B Neighboring gene semenogelin 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General protein information

Preferred Names
WAP four-disulfide core domain protein 15A
Names
WAP four-disulfide core domain-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008869.2NP_001008869.1  WAP four-disulfide core domain protein 15A precursor

    See identical proteins and their annotated locations for NP_001008869.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
    UniProtKB/TrEMBL
    A0A0G2K4P7, A6JX65, Q6IE39
    Related
    ENSRNOP00000073125.1, ENSRNOT00000090458.3
    Conserved Domains (1) summary
    pfam00095
    Location:3475
    WAP; WAP-type (Whey Acidic Protein) 'four-disulfide core'

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    173292668..173294900 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063284323.1XP_063140393.1  WAP four-disulfide core domain protein 15A isoform X1

    UniProtKB/TrEMBL
    A0A0G2K4P7, A6JX65, Q6IE39