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lsm14ab LSM14A mRNA processing body assembly factor b [ Danio rerio (zebrafish) ]

Gene ID: 406800, updated on 4-Jan-2025

Summary

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Official Symbol
lsm14abprovided by ZNC
Official Full Name
LSM14A mRNA processing body assembly factor bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2462
See related
Ensembl:ENSDARG00000100553 AllianceGenome:ZFIN:ZDB-GENE-040426-2462
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:55754; zgc:77202; wu:fc55d12
Summary
Predicted to enable mRNA binding activity. Predicted to be involved in P-body assembly and stress granule assembly. Predicted to be located in cytoplasm. Predicted to be active in P-body. Orthologous to human LSM14A (LSM14A mRNA processing body assembly factor). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See lsm14ab in Genome Data Viewer
Location:
chromosome: 18
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (302845..325512)
105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (413624..436294)

Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene transcription initiation factor TFIID subunit 4 Neighboring gene transcription initiation factor TFIID subunit 4 Neighboring gene si:ch211-79l17.1 Neighboring gene ss18, like 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. prpf4 is essential for cell survival and posterior lateral line primordium migration in zebrafish. Wang Y, et al. J Genet Genomics, 2018 Aug 20. PMID 30174136
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in P-body assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in stress granule assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in P-body IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
LSM14A mRNA processing body assembly factor b
Names
LSM14 homolog Ab
LSM14A, SCD6 homolog Ab

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_214772.2 → NP_999937.2  LSM14A mRNA processing body assembly factor b

    See identical proteins and their annotated locations for NP_999937.2

    Status: VALIDATED

    Source sequence(s)
    CU611056, CU627988
    UniProtKB/TrEMBL
    Q6P0B2, Q6PUR5
    Related
    ENSDARP00000139299.1, ENSDART00000160279.2
    Conserved Domains (2) summary
    pfam09532
    Location:260 → 376
    FDF; FDF domain
    pfam12701
    Location:6 → 80
    LSM14; Scd6-like Sm domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007129.7 Reference GRCz11 Primary Assembly

    Range
    302845..325512
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005158973.4 → XP_005159030.1  LSM14A mRNA processing body assembly factor b isoform X1

    UniProtKB/TrEMBL
    A0A0R4IVM1, A0A8M2B5Y4
    Related
    ENSDARP00000140356.1, ENSDART00000157434.2
    Conserved Domains (2) summary
    pfam09532
    Location:291 → 407
    FDF; FDF domain
    pfam12701
    Location:6 → 80
    LSM14; Scd6-like Sm domain

  2. XM_005158974.4 → XP_005159031.1  LSM14A mRNA processing body assembly factor b isoform X2

    UniProtKB/TrEMBL
    A0A8M2B5X3
    Conserved Domains (2) summary
    pfam09532
    Location:291 → 407
    FDF; FDF domain
    pfam12701
    Location:6 → 80
    LSM14; Scd6-like Sm domain

  3. XM_068214752.1 → XP_068070853.1  LSM14A mRNA processing body assembly factor b isoform X3

Nucleotide Protein Strain
Heading Accession and Version

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