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CG4049 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37860, updated on 4-Jan-2025

Summary

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Official Symbol
CG4049provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0034976
Locus tag
Dmel_CG4049
See related
AllianceGenome:FB:FBgn0034976
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Arip4; BEST:LD04705; Dmel\CG4049
Summary
Predicted to enable ATP-dependent chromatin remodeler activity and transcription coregulator activity. Predicted to be involved in chromatin organization. Predicted to be active in nucleus. Orthologous to human RAD54L2 (RAD54 like 2). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG4049 in Genome Data Viewer
Location:
60B10-60B10; 2-106 cM
Exon count:
8
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24107087..24114292, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (19994610..20001815, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene genghis khan Neighboring gene enoki mushroom Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A P element has induced intron formation in Drosophila. Nouaud D, et al. Mol Biol Evol, 1999 Nov. PMID 10555281
  2. CSB-independent, XPC-dependent transcription-coupled repair in Drosophila. Deger N, et al. Proc Natl Acad Sci U S A, 2022 Mar 1. PMID 35217627, Free PMC Article
  3. The XNP remodeler targets dynamic chromatin in Drosophila. Schneiderman JI, et al. Proc Natl Acad Sci U S A, 2009 Aug 25. PMID 19706533, Free PMC Article
  4. The NuRD nucleosome remodelling complex and NHK-1 kinase are required for chromosome condensation in oocytes. Nikalayevich E, et al. J Cell Sci, 2015 Feb 1. PMID 25501812, Free PMC Article
  5. The Adaptive Significance of Natural Genetic Variation in the DNA Damage Response of Drosophila melanogaster. Svetec N, et al. PLoS Genet, 2016 Mar. PMID 26950216, Free PMC Article

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP-dependent chromatin remodeler activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ATP-dependent chromatin remodeler activity IEA
Inferred from Electronic Annotation
more info
  
enables transcription coregulator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in chromatin organization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG4049-PA
R-gene

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    24107087..24114292 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_138041.3 → NP_611885.3  uncharacterized protein Dmel_CG4049 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611885.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W1A8
    Conserved Domains (3) summary
    cd00046
    Location:420 → 598
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd00079
    Location:958 → 1093
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam00176
    Location:394 → 730
    SNF2_N; SNF2 family N-terminal domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W1A8 Q9W1A8

Gene LinkOut

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