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CG34195 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37018, updated on 9-Dec-2024

Summary

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Official Symbol
CG34195provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0085224
Locus tag
Dmel_CG34195
See related
AllianceGenome:FB:FBgn0085224
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG4989; Dmel\CG34195; METTL6
Summary
Predicted to enable tRNA (cytidine) methyltransferase activity. Predicted to be involved in tRNA methylation. Is expressed in several structures, including anterior endoderm; embryonic/larval midgut; embryonic/larval midgut primordium; and posterior endoderm. Orthologous to human METTL6 (methyltransferase 6, tRNA N3-cytidine). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG34195 in Genome Data Viewer
Location:
54E4-54E4; 2-84 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (17733238..17734483)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (13620743..13621988)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Dachs ligand with SH3s Neighboring gene Sorting nexin 16 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene hyccin Neighboring gene Phosphatidylinositol glycan anchor biosynthesis class A Neighboring gene Vacuolar protein sorting 50

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The 18S ribosomal RNA m(6) A methyltransferase Mettl5 is required for normal walking behavior in Drosophila. Leismann J, et al. EMBO Rep, 2020 Jul 3. PMID 32350990, Free PMC Article
  2. Wolbachia and Virus Alter the Host Transcriptome at the Interface of Nucleotide Metabolism Pathways. Lindsey ARI, et al. mBio, 2021 Feb 9. PMID 33563832, Free PMC Article
  3. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article
  4. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article
  5. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables tRNA (cytidine) methyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in tRNA methylation ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG34195-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    17733238..17734483
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001103890.3 → NP_001097360.1  uncharacterized protein Dmel_CG34195 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001097360.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1ZAY5
    Conserved Domains (1) summary
    pfam08242
    Location:88 → 175
    Methyltransf_12; Methyltransferase domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A1ZAY5 A1ZAY5

Gene LinkOut

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