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CG5348 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36877, updated on 9-Dec-2024

Summary

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Official Symbol
CG5348provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0034156
Locus tag
Dmel_CG5348
See related
AllianceGenome:FB:FBgn0034156
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG5348
Summary
Predicted to enable calcium:sodium antiporter activity. Predicted to be involved in intracellular calcium ion homeostasis and monoatomic cation transport. Predicted to be active in membrane. Orthologous to human SLC8B1 (solute carrier family 8 member B1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See CG5348 in Genome Data Viewer
Location:
53D7-53D7; 2-80 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (16766804..16769238)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (12654309..12656743)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncoordinated-104 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Superoxide dismutase 2 (Mn) Neighboring gene Actin-related protein 53D

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The sexual identity of adult intestinal stem cells controls organ size and plasticity. Hudry B, et al. Nature, 2016 Feb 18. PMID 26887495, Free PMC Article
  2. New genes often acquire male-specific functions but rarely become essential in Drosophila. Kondo S, et al. Genes Dev, 2017 Sep 15. PMID 29051389, Free PMC Article
  3. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article
  4. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article
  5. Systematic genetic analysis of muscle morphogenesis and function in Drosophila. Schnorrer F, et al. Nature, 2010 Mar 11. PMID 20220848

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables calcium:sodium antiporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in intracellular calcium ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in monoatomic cation transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG5348-PB
CG5348-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    16766804..16769238
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001259446.2 → NP_001246375.1  uncharacterized protein Dmel_CG5348, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246375.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4K889
    Conserved Domains (1) summary
    pfam01699
    Location:86 → 186
    Na_Ca_ex; Sodium/calcium exchanger protein

  2. NM_137312.4 → NP_611156.3  uncharacterized protein Dmel_CG5348, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611156.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1ZAJ4
    Conserved Domains (1) summary
    pfam01699
    Location:458 → 603
    Na_Ca_ex; Sodium/calcium exchanger protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4K889 A0A0B4K889
A1ZAJ4 A1ZAJ4

Gene LinkOut

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