U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

dpr3 defective proboscis extension response 3 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 3346208, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
dpr3provided by FlyBase
Official Full Name
defective proboscis extension response 3provided by FlyBase
Primary source
FLYBASE:FBgn0053516
Locus tag
Dmel_CG33516
See related
AllianceGenome:FB:FBgn0053516
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG15379; CG15380; CG15381; CG33516; CRACM2; CT35425; Dmel\CG33516; Dpr-3; Dpr3
Summary
Involved in store-operated calcium entry and synapse organization. Predicted to be located in plasma membrane. Predicted to be active in neuron projection membrane. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See dpr3 in Genome Data Viewer
Location:
22C1-22C3; 2-4 cM
Exon count:
8
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2058790..2109878, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2058790..2109878, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Kinetochore and EB1 associated basic protein Neighboring gene Odorant receptor 22c Neighboring gene long non-coding RNA:CR44808 Neighboring gene long non-coding RNA:CR44055 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Glycogen phosphorylase

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry. Vig M, et al. Science, 2006 May 26. PMID 16645049, Free PMC Article
  2. Modular transcriptional programs separately define axon and dendrite connectivity. Kurmangaliyev YZ, et al. Elife, 2019 Nov 5. PMID 31687928, Free PMC Article
  3. Combinations of DIPs and Dprs control organization of olfactory receptor neuron terminals in Drosophila. Barish S, et al. PLoS Genet, 2018 Aug. PMID 30102700, Free PMC Article
  4. Defective proboscis extension response (DPR), a member of the Ig superfamily required for the gustatory response to salt. Nakamura M, et al. J Neurosci, 2002 May 1. PMID 11978823, Free PMC Article
  5. Neural immunoglobulin superfamily interaction networks. Zinn K, et al. Curr Opin Neurobiol, 2017 Aug. PMID 28558267, Free PMC Article

See all (43) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

mobile_element

  • Loc: c2109522-2100430 mobile_element_type = transposon:roo{}2620

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in sensory perception of chemical stimulus ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in store-operated calcium entry IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in synapse organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in synapse organization IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
is_active_in neuron projection membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
defective proboscis extension response 3
Names
CG33516-PB
CG33516-PC
CG33516-PD
CRAC modulator 2
dpr3-PB
dpr3-PC
dpr3-PD

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    2058790..2109878 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001272973.1 → NP_001259902.1  defective proboscis extension response 3, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259902.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q59E13
    Conserved Domains (2) summary
    smart00410
    Location:243 → 329
    IG_like; Immunoglobulin like
    cl11960
    Location:243 → 330
    Ig; Immunoglobulin domain

  2. NM_001014459.2 → NP_001014459.2  defective proboscis extension response 3, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001014459.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q59E13
    Conserved Domains (2) summary
    smart00410
    Location:243 → 329
    IG_like; Immunoglobulin like
    cl11960
    Location:243 → 330
    Ig; Immunoglobulin domain

  3. NM_001272972.1 → NP_001259901.1  defective proboscis extension response 3, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259901.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q59E13
    Conserved Domains (2) summary
    smart00410
    Location:243 → 329
    IG_like; Immunoglobulin like
    cl11960
    Location:243 → 330
    Ig; Immunoglobulin domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q59E13 Q59E13

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools