U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ankmy2a ankyrin repeat and MYND domain containing 2a [ Danio rerio (zebrafish) ]

Gene ID: 334389, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
ankmy2aprovided by ZNC
Official Full Name
ankyrin repeat and MYND domain containing 2aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-6321
See related
Ensembl:ENSDARG00000005948 AllianceGenome:ZFIN:ZDB-GENE-030131-6321
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fi46e08; zgc:55491; wu:fi46e08
Summary
Predicted to enable metal ion binding activity. Acts upstream of or within regulation of smoothened signaling pathway. Predicted to be located in cilium. Is expressed in neural tube. Orthologous to human ANKMY2 (ankyrin repeat and MYND domain containing 2). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See ankmy2a in Genome Data Viewer
Location:
chromosome: 15
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (34573311..34590820, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (34715342..34732851, complement)

Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene mesenchyme homeobox 2a Neighboring gene CDP-L-ribitol pyrophosphorylase A Neighboring gene sclerostin domain containing 1a Neighboring gene leucine rich repeat containing 72 Neighboring gene tetraspanin 13a Neighboring gene LINE-1 reverse transcriptase homolog

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Role of the ANKMY2-FKBP38 axis in regulation of the Sonic hedgehog (Shh) signaling pathway. Saita S, et al. J Biol Chem, 2014 Sep 12. PMID 25077969, Free PMC Article
  2. The zebrafish maternal-effect gene mission impossible encodes the DEAH-box helicase Dhx16 and is essential for the expression of downstream endodermal genes. Putiri E, et al. Dev Biol, 2011 May 15. PMID 21396359, Free PMC Article
  3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of smoothened signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
is_active_in cellular_component ND
No biological Data available
more info
  
located_in cilium IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
ankyrin repeat and MYND domain-containing protein 2a

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199894.1 → NP_956188.1  ankyrin repeat and MYND domain-containing protein 2a

    See identical proteins and their annotated locations for NP_956188.1

    Status: PROVISIONAL

    Source sequence(s)
    BC044410
    UniProtKB/TrEMBL
    Q803N0
    Related
    ENSDARP00000003452.6, ENSDART00000003674.8
    Conserved Domains (4) summary
    cd00204
    Location:16 → 132
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam01753
    Location:320 → 357
    zf-MYND; MYND finger
    pfam12796
    Location:16 → 110
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:16 → 43
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007126.7 Reference GRCz11 Primary Assembly

    Range
    34573311..34590820 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools