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Conserved domains on  [gi|41054031|ref|NP_956188|]
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ankyrin repeat and MYND domain-containing protein 2a [Danio rerio]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
16-129 5.66e-25

Ankyrin repeat [Signal transduction mechanisms];


:

Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 103.50  E-value: 5.66e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41054031  16 LLQVIAAGNVQEASRLLgSKDVKVNCLDEYGMTPLMHAAYKGKADMCKLLLQHGADVNCnEHEHGYTALMFAGLSGKTEI 95
Cdd:COG0666  91 LHAAARNGDLEIVKLLL-EAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNA-QDNDGNTPLHLAAANGNLEI 168

                        90       100       110
                ....*....|....*....|....*....|....
gi 41054031  96 TWMMLDAGAETDAVNSVGRTAAQMAAFVGQHDCV 129
Cdd:COG0666 169 VKLLLEAGADVNARDNDGETPLHLAAENGHLEIV 202
zf-MYND pfam01753
MYND finger;
320-357 9.18e-11

MYND finger;


:

Pssm-ID: 460312  Cd Length: 39  Bit Score: 56.66  E-value: 9.18e-11
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 41054031   320 CTTCGEKGAE-KRCSICKMVIYCGQACQKLHWFSHKKVC 357
Cdd:pfam01753   1 CAVCGKEALKlLRCSRCKSVYYCSKECQKADWPYHKKEC 39
Ank_2 super family cl48147
Ankyrin repeats (3 copies);
84-190 1.87e-05

Ankyrin repeats (3 copies);


The actual alignment was detected with superfamily member pfam12796:

Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 42.80  E-value: 1.87e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41054031    84 LMFAGLSGKTEITWMMLDAGAETDAVNSVGRTAAQMAAFVGQHDCVTV-INNFFSRARLDYYTkpqglekepklppklsg 162
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLlLEHADVNLKDNGRT----------------- 63

                          90       100
                  ....*....|....*....|....*...
gi 41054031   163 PLHKIIMSTNLNPVKIVMMVKENPLLMD 190
Cdd:pfam12796  64 ALHYAARSGHLEIVKLLLEKGADINVKD 91
 
Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
16-129 5.66e-25

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 103.50  E-value: 5.66e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41054031  16 LLQVIAAGNVQEASRLLgSKDVKVNCLDEYGMTPLMHAAYKGKADMCKLLLQHGADVNCnEHEHGYTALMFAGLSGKTEI 95
Cdd:COG0666  91 LHAAARNGDLEIVKLLL-EAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNA-QDNDGNTPLHLAAANGNLEI 168

                        90       100       110
                ....*....|....*....|....*....|....
gi 41054031  96 TWMMLDAGAETDAVNSVGRTAAQMAAFVGQHDCV 129
Cdd:COG0666 169 VKLLLEAGADVNARDNDGETPLHLAAENGHLEIV 202
Ank_2 pfam12796
Ankyrin repeats (3 copies);
16-110 2.18e-14

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 68.22  E-value: 2.18e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41054031    16 LLQVIAAGNVQEASRLLgSKDVKVNCLDEYGMTPLMHAAYKGKADMCKLLLQHgadVNCNEHEHGYTALMFAGLSGKTEI 95
Cdd:pfam12796   1 LHLAAKNGNLELVKLLL-ENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH---ADVNLKDNGRTALHYAARSGHLEI 76

                          90
                  ....*....|....*
gi 41054031    96 TWMMLDAGAETDAVN 110
Cdd:pfam12796  77 VKLLLEKGADINVKD 91
zf-MYND pfam01753
MYND finger;
320-357 9.18e-11

MYND finger;


Pssm-ID: 460312  Cd Length: 39  Bit Score: 56.66  E-value: 9.18e-11
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 41054031   320 CTTCGEKGAE-KRCSICKMVIYCGQACQKLHWFSHKKVC 357
Cdd:pfam01753   1 CAVCGKEALKlLRCSRCKSVYYCSKECQKADWPYHKKEC 39
PHA03100 PHA03100
ankyrin repeat protein; Provisional
 31-111 1.05e-07

ankyrin repeat protein; Provisional


Pssm-ID: 222984 [Multi-domain]  Cd Length: 422  Bit Score: 53.52  E-value: 1.05e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41054031   31 LLGSKDVKVNCLDEYGMTPLMHAAYKGKADMCKLLLQHGADVN-CNehEHGYTALMFAGLSGKTEITWMMLDAGAETDAV 109
Cdd:PHA03100 177 YLLSYGVPINIKDVYGFTPLHYAVYNNNPEFVKYLLDLGANPNlVN--KYGDTPLHIAILNNNKEIFKLLLNNGPSIKTI 254


                 ..
gi 41054031  110 NS 111
Cdd:PHA03100 255 IE 256
ANK smart00248
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...
 45-74 2.89e-07

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.


Pssm-ID: 197603 [Multi-domain]  Cd Length: 30  Bit Score: 46.43  E-value: 2.89e-07
                           10        20        30
                   ....*....|....*....|....*....|
gi 41054031     45 YGMTPLMHAAYKGKADMCKLLLQHGADVNC 74
Cdd:smart00248   1 DGRTPLHLAAENGNLEVVKLLLDKGADINA 30
Ank_2 pfam12796
Ankyrin repeats (3 copies);
84-190 1.87e-05

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 42.80  E-value: 1.87e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41054031    84 LMFAGLSGKTEITWMMLDAGAETDAVNSVGRTAAQMAAFVGQHDCVTV-INNFFSRARLDYYTkpqglekepklppklsg 162
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLlLEHADVNLKDNGRT----------------- 63

                          90       100
                  ....*....|....*....|....*...
gi 41054031   163 PLHKIIMSTNLNPVKIVMMVKENPLLMD 190
Cdd:pfam12796  64 ALHYAARSGHLEIVKLLLEKGADINVKD 91
 
Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
16-129 5.66e-25

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 103.50  E-value: 5.66e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41054031  16 LLQVIAAGNVQEASRLLgSKDVKVNCLDEYGMTPLMHAAYKGKADMCKLLLQHGADVNCnEHEHGYTALMFAGLSGKTEI 95
Cdd:COG0666  91 LHAAARNGDLEIVKLLL-EAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNA-QDNDGNTPLHLAAANGNLEI 168

                        90       100       110
                ....*....|....*....|....*....|....
gi 41054031  96 TWMMLDAGAETDAVNSVGRTAAQMAAFVGQHDCV 129
Cdd:COG0666 169 VKLLLEAGADVNARDNDGETPLHLAAENGHLEIV 202
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
16-129 1.56e-24

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 102.34  E-value: 1.56e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41054031  16 LLQVIAAGNVQEASRLLgSKDVKVNCLDEYGMTPLMHAAYKGKADMCKLLLQHGADVNcNEHEHGYTALMFAGLSGKTEI 95
Cdd:COG0666 124 LHLAAYNGNLEIVKLLL-EAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVN-ARDNDGETPLHLAAENGHLEI 201

                        90       100       110
                ....*....|....*....|....*....|....
gi 41054031  96 TWMMLDAGAETDAVNSVGRTAAQMAAFVGQHDCV 129
Cdd:COG0666 202 VKLLLEAGADVNAKDNDGKTALDLAAENGNLEIV 235
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
16-129 2.44e-16

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 78.84  E-value: 2.44e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41054031  16 LLQVIAAGNVQEASRLLgSKDVKVNCLDEYGMTPLMHAAYKGKADMCKLLLQHGADVNcNEHEHGYTALMFAGLSGKTEI 95
Cdd:COG0666 157 LHLAAANGNLEIVKLLL-EAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVN-AKDNDGKTALDLAAENGNLEI 234

                        90       100       110
                ....*....|....*....|....*....|....
gi 41054031  96 TWMMLDAGAETDAVNSVGRTAAQMAAFVGQHDCV 129
Cdd:COG0666 235 VKLLLEAGADLNAKDKDGLTALLLAAAAGAALIV 268
Ank_2 pfam12796
Ankyrin repeats (3 copies);
16-110 2.18e-14

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 68.22  E-value: 2.18e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41054031    16 LLQVIAAGNVQEASRLLgSKDVKVNCLDEYGMTPLMHAAYKGKADMCKLLLQHgadVNCNEHEHGYTALMFAGLSGKTEI 95
Cdd:pfam12796   1 LHLAAKNGNLELVKLLL-ENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH---ADVNLKDNGRTALHYAARSGHLEI 76

                          90
                  ....*....|....*
gi 41054031    96 TWMMLDAGAETDAVN 110
Cdd:pfam12796  77 VKLLLEKGADINVKD 91
zf-MYND pfam01753
MYND finger;
320-357 9.18e-11

MYND finger;


Pssm-ID: 460312  Cd Length: 39  Bit Score: 56.66  E-value: 9.18e-11
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 41054031   320 CTTCGEKGAE-KRCSICKMVIYCGQACQKLHWFSHKKVC 357
Cdd:pfam01753   1 CAVCGKEALKlLRCSRCKSVYYCSKECQKADWPYHKKEC 39
Ank_5 pfam13857
Ankyrin repeats (many copies);
39-87 2.83e-09

Ankyrin repeats (many copies);


Pssm-ID: 433530 [Multi-domain]  Cd Length: 56  Bit Score: 52.73  E-value: 2.83e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 41054031    39 VNCLDEYGMTPLMHAAYKGKADMCKLLLQHGADVNCNEhEHGYTALMFA 87
Cdd:pfam13857   9 LNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKD-EEGLTALDLA 56
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
5-129 6.29e-09

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 56.89  E-value: 6.29e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41054031   5 KKGDLTDTEKELLQVIAAGNVQEASRLLGSKDVKVNCLDEYGMTPLMHAAYKGKADMCKLLLQHGADVNCNEHEHGYTAL 84
Cdd:COG0666  12 LAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLL 91

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*
gi 41054031  85 MFAGLSGKTEITWMMLDAGAETDAVNSVGRTAAQMAAFVGQHDCV 129
Cdd:COG0666  92 HAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIV 136
PHA03100 PHA03100
ankyrin repeat protein; Provisional
 31-111 1.05e-07

ankyrin repeat protein; Provisional


Pssm-ID: 222984 [Multi-domain]  Cd Length: 422  Bit Score: 53.52  E-value: 1.05e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41054031   31 LLGSKDVKVNCLDEYGMTPLMHAAYKGKADMCKLLLQHGADVN-CNehEHGYTALMFAGLSGKTEITWMMLDAGAETDAV 109
Cdd:PHA03100 177 YLLSYGVPINIKDVYGFTPLHYAVYNNNPEFVKYLLDLGANPNlVN--KYGDTPLHIAILNNNKEIFKLLLNNGPSIKTI 254


                 ..
gi 41054031  110 NS 111
Cdd:PHA03100 255 IE 256
ANK smart00248
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...
 45-74 2.89e-07

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.


Pssm-ID: 197603 [Multi-domain]  Cd Length: 30  Bit Score: 46.43  E-value: 2.89e-07
                           10        20        30
                   ....*....|....*....|....*....|
gi 41054031     45 YGMTPLMHAAYKGKADMCKLLLQHGADVNC 74
Cdd:smart00248   1 DGRTPLHLAAENGNLEVVKLLLDKGADINA 30
Ank_4 pfam13637
Ankyrin repeats (many copies);
46-95 4.28e-07

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 46.50  E-value: 4.28e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 41054031    46 GMTPLMHAAYKGKADMCKLLLQHGADVNCNEHEhGYTALMFAGLSGKTEI 95
Cdd:pfam13637   1 ELTALHAAAASGHLELLRLLLEKGADINAVDGN-GETALHFAASNGNVEV 49
Ank pfam00023
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...
 45-74 1.18e-06

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.


Pssm-ID: 459634 [Multi-domain]  Cd Length: 34  Bit Score: 44.59  E-value: 1.18e-06
                          10        20        30
                  ....*....|....*....|....*....|.
gi 41054031    45 YGMTPLMHAAYK-GKADMCKLLLQHGADVNC 74
Cdd:pfam00023   1 DGNTPLHLAAGRrGNLEIVKLLLSKGADVNA 31
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
16-117 1.60e-06

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 49.57  E-value: 1.60e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41054031  16 LLQVIAAGNVQEASRLLgSKDVKVNCLDEYGMTPLMHAAYKGKADMCKLLLQHGADVNcNEHEHGYTALMFAGLSGKTEI 95
Cdd:COG0666 190 LHLAAENGHLEIVKLLL-EAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLN-AKDKDGLTALLLAAAAGAALI 267

                        90       100
                ....*....|....*....|..
gi 41054031  96 TWMMLDAGAETDAVNSVGRTAA 117
Cdd:COG0666 268 VKLLLLALLLLAAALLDLLTLL 289
PHA03095 PHA03095
ankyrin-like protein; Provisional
 30-116 1.65e-06

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 50.02  E-value: 1.65e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41054031   30 RLLGSKDVKVNCLDEYGMTPL---MHAAYKGKADMCKLLLQHGADVNCNEhEHGYTALMFAGLSGKTE-ITWMMLDAGAE 105
Cdd:PHA03095  31 RRLLAAGADVNFRGEYGKTPLhlyLHYSSEKVKDIVRLLLEAGADVNAPE-RCGFTPLHLYLYNATTLdVIKLLIKAGAD 109

                         90
                 ....*....|.
gi 41054031  106 TDAVNSVGRTA 116
Cdd:PHA03095 110 VNAKDKVGRTP 120
PHA03095 PHA03095
ankyrin-like protein; Provisional
 23-146 2.64e-06

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 49.25  E-value: 2.64e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41054031   23 GNVQEASRLLGSKDVKVNCLDEYGMTPL-MHAAYKGKADMCKLLLQHGADVNcNEHEHGYTAL--MFAGLSGKTEITWMM 99
Cdd:PHA03095  60 EKVKDIVRLLLEAGADVNAPERCGFTPLhLYLYNATTLDVIKLLIKAGADVN-AKDKVGRTPLhvYLSGFNINPKVIRLL 138

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 41054031  100 LDAGAETDAVNSVGRTAaqMAAFVGQHDCVTVINNFFSRARLDYYTK 146
Cdd:PHA03095 139 LRKGADVNALDLYGMTP--LAVLLKSRNANVELLRLLIDAGADVYAV 183
Ank_3 pfam13606
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...
 45-74 2.76e-06

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities.


Pssm-ID: 463933 [Multi-domain]  Cd Length: 30  Bit Score: 43.40  E-value: 2.76e-06
                          10        20        30
                  ....*....|....*....|....*....|
gi 41054031    45 YGMTPLMHAAYKGKADMCKLLLQHGADVNC 74
Cdd:pfam13606   1 DGNTPLHLAARNGRLEIVKLLLENGADINA 30
PHA02875 PHA02875
ankyrin repeat protein; Provisional
 11-138 4.93e-06

ankyrin repeat protein; Provisional


Pssm-ID: 165206 [Multi-domain]  Cd Length: 413  Bit Score: 48.45  E-value: 4.93e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41054031   11 DTEKELLQVIAAGNVQEASRLLGSKDVKVNCLDEYGMTPLMHAAYKGKADMCKLLLQHGADVNCN--------------- 75
Cdd:PHA02875  67 DIESELHDAVEEGDVKAVEELLDLGKFADDVFYKDGMTPLHLATILKKLDIMKLLIARGADPDIPntdkfsplhlavmmg 146

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41054031   76 -----------------EHEHGYTALMFAGLSGKTEITWMMLDAGAETDAVNSVGRTAAQMAAFvgQHDCVTVINNFFSR 138
Cdd:PHA02875 147 dikgiellidhkacldiEDCCGCTPLIIAMAKGDIAICKMLLDSGANIDYFGKNGCVAALCYAI--ENNKIDIVRLFIKR 224
PHA03100 PHA03100
ankyrin repeat protein; Provisional
 31-226 1.15e-05

ankyrin repeat protein; Provisional


Pssm-ID: 222984 [Multi-domain]  Cd Length: 422  Bit Score: 47.35  E-value: 1.15e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41054031   31 LLGSKDVKVNCLDEYGMTPLmHAAYKG---KADMCKLLLQHGADVN-CNE--------------HEHGYTALMFAGLSGK 92
Cdd:PHA03100 126 YLLDNGANVNIKNSDGENLL-HLYLESnkiDLKILKLLIDKGVDINaKNRvnyllsygvpinikDVYGFTPLHYAVYNNN 204

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41054031   93 TEITWMMLDAGAETDAVNSVGRTAAQMAAfvgqHDCVTVINNFFSRARLDYYTKPQGLEKEPKLPPklsgplhKIIMSTN 172
Cdd:PHA03100 205 PEFVKYLLDLGANPNLVNKYGDTPLHIAI----LNNNKEIFKLLLNNGPSIKTIIETLLYFKDKDL-------NTITKIK 273

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 41054031  173 LNPVKIVMMVKENPLLM-DVEALEKCRKVLELIcEKCIKqqdmnEVLAMKMHYLS 226
Cdd:PHA03100 274 MLKKSIMYMFLLDPGFYkNRKLIENSKSLKDVI-NECEK-----EIERMKEIKLN 322
Ank_4 pfam13637
Ankyrin repeats (many copies);
16-66 1.84e-05

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 41.88  E-value: 1.84e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 41054031    16 LLQVIAAGNVQEASRLLGSKdVKVNCLDEYGMTPLMHAAYKGKADMCKLLL 66
Cdd:pfam13637   5 LHAAAASGHLELLRLLLEKG-ADINAVDGNGETALHFAASNGNVEVLKLLL 54
Ank_2 pfam12796
Ankyrin repeats (3 copies);
84-190 1.87e-05

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 42.80  E-value: 1.87e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41054031    84 LMFAGLSGKTEITWMMLDAGAETDAVNSVGRTAAQMAAFVGQHDCVTV-INNFFSRARLDYYTkpqglekepklppklsg 162
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLlLEHADVNLKDNGRT----------------- 63

                          90       100
                  ....*....|....*....|....*...
gi 41054031   163 PLHKIIMSTNLNPVKIVMMVKENPLLMD 190
Cdd:pfam12796  64 ALHYAARSGHLEIVKLLLEKGADINVKD 91
PHA02875 PHA02875
ankyrin repeat protein; Provisional
 10-112 2.67e-05

ankyrin repeat protein; Provisional


Pssm-ID: 165206 [Multi-domain]  Cd Length: 413  Bit Score: 46.14  E-value: 2.67e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41054031   10 TDTEKELLQVIAAGNVQEASRLLGSKdVKVNCLDEYGMTPLMHAAYKGKADMCKLLLQHGADVNCNEHEHGYTALMFAGL 89
Cdd:PHA02875 133 TDKFSPLHLAVMMGDIKGIELLIDHK-ACLDIEDCCGCTPLIIAMAKGDIAICKMLLDSGANIDYFGKNGCVAALCYAIE 211

                         90       100
                 ....*....|....*....|...
gi 41054031   90 SGKTEITWMMLDAGAETDAVNSV 112
Cdd:PHA02875 212 NNKIDIVRLFIKRGADCNIMFMI 234
PHA03095 PHA03095
ankyrin-like protein; Provisional
 23-116 3.99e-05

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 45.79  E-value: 3.99e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41054031   23 GNVQEASRLLGSKDVKVNCLDEYGMTPLmHAAYKGK---ADMCKLLLQHGADVNcNEHEHGYTALmFAGLSGKT---EIT 96
Cdd:PHA03095  94 ATTLDVIKLLIKAGADVNAKDKVGRTPL-HVYLSGFninPKVIRLLLRKGADVN-ALDLYGMTPL-AVLLKSRNanvELL 170

                         90       100
                 ....*....|....*....|
gi 41054031   97 WMMLDAGAETDAVNSVGRTA 116
Cdd:PHA03095 171 RLLIDAGADVYAVDDRFRSL 190
PTZ00322 PTZ00322
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
 50-154 3.04e-04

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional


Pssm-ID: 140343 [Multi-domain]  Cd Length: 664  Bit Score: 42.96  E-value: 3.04e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41054031   50 LMHAAYKGKADMCKLLLQHGADVNCNEHeHGYTALMFAGLSGKTEITWMMLDAGAETDAVNSVGRTAAQMAAFVGQHDCV 129
Cdd:PTZ00322  86 LCQLAASGDAVGARILLTGGADPNCRDY-DGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVV 164

                         90       100       110
                 ....*....|....*....|....*....|...
gi 41054031  130 TVI-------NNFFSRARLDYYT-KPQGLEKEP 154
Cdd:PTZ00322 165 QLLsrhsqchFELGANAKPDSFTgKPPSLEDSP 197
PHA02876 PHA02876
ankyrin repeat protein; Provisional
 29-73 3.14e-04

ankyrin repeat protein; Provisional


Pssm-ID: 165207 [Multi-domain]  Cd Length: 682  Bit Score: 43.13  E-value: 3.14e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 41054031   29 SRLLGSKDVKVNCLDEYGMTPLMHAAYKGKADMCKLLLQHGADVN 73
Cdd:PHA02876 161 AEMLLEGGADVNAKDIYCITPIHYAAERGNAKMVNLLLSYGADVN 205
PTZ00322 PTZ00322
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
 15-100 4.99e-04

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional


Pssm-ID: 140343 [Multi-domain]  Cd Length: 664  Bit Score: 42.19  E-value: 4.99e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41054031   15 ELLQVIAAGNVQEAsRLLGSKDVKVNCLDEYGMTPLMHAAYKGKADMCKLLLQHGADVNCNEHEhGYTALMFAGLSGKTE 94
Cdd:PTZ00322  85 ELCQLAASGDAVGA-RILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKD-GKTPLELAEENGFRE 162


                 ....*.
gi 41054031   95 ITWMML 100
Cdd:PTZ00322 163 VVQLLS 168
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 37-132 1.14e-03

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 41.10  E-value: 1.14e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41054031   37 VKVNCLDEYGMTPLMHAAYKGKADMCKLLLQHGADVNCnEHEHGYTALMFAGLSGKTEITWMMLDAGAETDAVNSVGRTA 116
Cdd:PHA02874 115 IDVNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNI-EDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESP 193

                         90
                 ....*....|....*.
gi 41054031  117 AQMAAFVGQHDCVTVI 132
Cdd:PHA02874 194 LHNAAEYGDYACIKLL 209
PHA02798 PHA02798
ankyrin-like protein; Provisional
 38-146 1.63e-03

ankyrin-like protein; Provisional


Pssm-ID: 222931 [Multi-domain]  Cd Length: 489  Bit Score: 40.59  E-value: 1.63e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41054031   38 KVNCLDEYGMTPLMH-----AAYKGKADMCKLLLQHGADVNcNEHEHGYTALmFAGLSGKT----EITWMMLDAGAETDA 108
Cdd:PHA02798  63 NVNGLDNEYSTPLCTilsniKDYKHMLDIVKILIENGADIN-KKNSDGETPL-YCLLSNGYinnlEILLFMIENGADTTL 140

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 41054031  109 VNSVGRTAAQMAAFVGQHDCVTVI-------------NNFFSRARLDYYTK 146
Cdd:PHA02798 141 LDKDGFTMLQVYLQSNHHIDIEIIklllekgvdinthNNKEKYDTLHCYFK 191
PHA03100 PHA03100
ankyrin repeat protein; Provisional
 6-112 1.70e-03

ankyrin repeat protein; Provisional


Pssm-ID: 222984 [Multi-domain]  Cd Length: 422  Bit Score: 40.42  E-value: 1.70e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41054031    6 KGDLTDTEKELLQVIAAGNVQEASRLLGSKDVKVNCLDEYGMTPLMHAAYK--GKADMCKLLLQHGADVNCNEHEhGYTA 83
Cdd:PHA03100  66 KNNSTPLHYLSNIKYNLTDVKEIVKLLLEYGANVNAPDNNGITPLLYAISKksNSYSIVEYLLDNGANVNIKNSD-GENL 144

                         90       100       110
                 ....*....|....*....|....*....|..
gi 41054031   84 LMFAgLSG---KTEITWMMLDAGAETDAVNSV 112
Cdd:PHA03100 145 LHLY-LESnkiDLKILKLLIDKGVDINAKNRV 175
PHA02859 PHA02859
ankyrin repeat protein; Provisional
 39-115 1.73e-03

ankyrin repeat protein; Provisional


Pssm-ID: 165195 [Multi-domain]  Cd Length: 209  Bit Score: 39.42  E-value: 1.73e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41054031   39 VNCLDEYGMTPLMHAAYKGKA--DMCKLLLQHGADVNCNEHEHGYTALMFAGLSGKT---EITWMMLDAGAETDAVNSVG 113
Cdd:PHA02859  44 VNDCNDLYETPIFSCLEKDKVnvEILKFLIENGADVNFKTRDNNLSALHHYLSFNKNvepEILKILIDSGSSITEEDEDG 123


                 ..
gi 41054031  114 RT 115
Cdd:PHA02859 124 KN 125
Ank_5 pfam13857
Ankyrin repeats (many copies);
65-120 2.25e-03

Ankyrin repeats (many copies);


Pssm-ID: 433530 [Multi-domain]  Cd Length: 56  Bit Score: 36.17  E-value: 2.25e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 41054031    65 LLQHGaDVNCN-EHEHGYTALMFAGLSGKTEITWMMLDAGAETDAVNSVGRTAAQMA 120
Cdd:pfam13857   1 LLEHG-PIDLNrLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
PHA02878 PHA02878
ankyrin repeat protein; Provisional
 11-120 2.95e-03

ankyrin repeat protein; Provisional


Pssm-ID: 222939 [Multi-domain]  Cd Length: 477  Bit Score: 39.86  E-value: 2.95e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41054031   11 DTEKELLQVIAAGNVQEASRLLGSKDVKVNCLDEYGMTPLMHAAYKGKADMCKLLLQHGADVNCNEhEHGYTALMFAGLS 90
Cdd:PHA02878 166 HKGNTALHYATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGASTDARD-KCGNTPLHISVGY 244

                         90       100       110
                 ....*....|....*....|....*....|..
gi 41054031   91 GKT-EITWMMLDAGAETDAVNSV-GRTAAQMA 120
Cdd:PHA02878 245 CKDyDILKLLLEHGVDVNAKSYIlGLTALHSS 276
PLN03192 PLN03192
Voltage-dependent potassium channel; Provisional
 16-99 4.28e-03

Voltage-dependent potassium channel; Provisional


Pssm-ID: 215625 [Multi-domain]  Cd Length: 823  Bit Score: 39.47  E-value: 4.28e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41054031   16 LLQVIAAGNVQEASRLL-GSKDVKVNclDEYGMTPLMHAAYKGKADMCKLLLQHGADVNCNEhEHGYTALMFAGLSGKTE 94
Cdd:PLN03192 529 LLTVASTGNAALLEELLkAKLDPDIG--DSKGRTPLHIAASKGYEDCVLVLLKHACNVHIRD-ANGNTALWNAISAKHHK 605


                 ....*
gi 41054031   95 ITWMM 99
Cdd:PLN03192 606 IFRIL 610
PLN03192 PLN03192
Voltage-dependent potassium channel; Provisional
 50-110 8.11e-03

Voltage-dependent potassium channel; Provisional


Pssm-ID: 215625 [Multi-domain]  Cd Length: 823  Bit Score: 38.70  E-value: 8.11e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 41054031   50 LMHAAYKGKADMCKLLLQHGADVNCNEHeHGYTALMFAGLSGKTEITWMMLDAGAETDAVN 110
Cdd:PLN03192 626 LCTAAKRNDLTAMKELLKQGLNVDSEDH-QGATALQVAMAEDHVDMVRLLIMNGADVDKAN 685
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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