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mRpL10 mitochondrial ribosomal protein L10 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33182, updated on 4-Jan-2025

Summary

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Official Symbol
mRpL10provided by FlyBase
Official Full Name
mitochondrial ribosomal protein L10provided by FlyBase
Primary source
FLYBASE:FBgn0031231
Locus tag
Dmel_CG11488
See related
AllianceGenome:FB:FBgn0031231
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG11488; Dmel\CG11488; L10; RpL10
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be part of mitochondrial large ribosomal subunit. Is expressed in adult head; adult heart; embryonic/larval midgut; and organism. Orthologous to human MRPL10 (mitochondrial ribosomal protein L10). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See mRpL10 in Genome Data Viewer
Location:
21B4-21B4; 2-0.5 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (203779..204782)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (203779..204782)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene split ends Neighboring gene TBC1 domain family member 15/17 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44220 Neighboring gene kismet

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mitochondrial Ribosomal Protein L10 Associates with Cyclin B1/Cdk1 Activity and Mitochondrial Function. Li HB, et al. DNA Cell Biol, 2016 Nov. PMID 27726420, Free PMC Article
  2. Genome-wide analysis of promoter architecture in Drosophila melanogaster. Hoskins RA, et al. Genome Res, 2011 Feb. PMID 21177961, Free PMC Article
  3. DREF is required for cell and organismal growth in Drosophila and functions downstream of the nutrition/TOR pathway. Killip LE, et al. Dev Biol, 2012 Nov 15. PMID 22960233
  4. Whole genome screen reveals a novel relationship between Wolbachia levels and Drosophila host translation. Grobler Y, et al. PLoS Pathog, 2018 Nov. PMID 30422992, Free PMC Article
  5. Cardiomyopathy is associated with ribosomal protein gene haplo-insufficiency in Drosophila melanogaster. Casad ME, et al. Genetics, 2011 Nov. PMID 21890737, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome ISS
Inferred from Sequence or Structural Similarity
more info
  
enables structural constituent of ribosome TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitochondrial translation TAS
Traceable Author Statement
more info
 PubMed 
involved_in translation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in translation ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
part_of mitochondrial large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial large ribosomal subunit ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of mitochondrial large ribosomal subunit TAS
Traceable Author Statement
more info
 PubMed 
part_of ribonucleoprotein complex ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
mitochondrial ribosomal protein L10
Names
CG11488-PA
mRpL10-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    203779..204782
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_078716.3 → NP_523440.1  mitochondrial ribosomal protein L10 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_523440.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VPL3
    Related
    FBpp0077783
    Conserved Domains (1) summary
    cd05797
    Location:74 → 227
    Ribosomal_L10; Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VPL3.1 Q9VPL3

Gene LinkOut

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