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Obp8a Odorant-binding protein 8a [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31860, updated on 9-Dec-2024

Summary

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Official Symbol
Obp8aprovided by FlyBase
Official Full Name
Odorant-binding protein 8aprovided by FlyBase
Primary source
FLYBASE:FBgn0030103
Locus tag
Dmel_CG12665
See related
AllianceGenome:FB:FBgn0030103
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
8a; CG12665; DmelObp8a; Dmel\CG12665; OBP8a
Summary
Predicted to enable odorant binding activity. Predicted to be involved in sensory perception of smell. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See Obp8a in Genome Data Viewer
Location:
8D1-8D1; 1-27 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (9214876..9215699)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (9108909..9109732)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene suppressor of rudimentary Neighboring gene SET and MYND domain containing, arthropod-specific, member 9 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Natural variation, functional pleiotropy and transcriptional contexts of odorant binding protein genes in Drosophila melanogaster. Arya GH, et al. Genetics, 2010 Dec. PMID 20870963, Free PMC Article
  2. The seminal odorant binding protein Obp56g is required for mating plug formation and male fertility in Drosophila melanogaster. Brown NC, et al. Elife, 2023 Dec 21. PMID 38126735, Free PMC Article
  3. Regulatory divergence in Drosophila melanogaster and D. simulans, a genomewide analysis of allele-specific expression. Graze RM, et al. Genetics, 2009 Oct. PMID 19667135, Free PMC Article
  4. Microarray-based capture of novel expressed cell type-specific transfrags (CoNECT) to annotate tissue-specific transcription in Drosophila melanogaster. Hong X, et al. G3 (Bethesda), 2012 Aug. PMID 22908036, Free PMC Article
  5. The odorant-binding proteins of Drosophila melanogaster: annotation and characterization of a divergent gene family. Graham LA, et al. Gene, 2002 Jun 12. PMID 12119098

See all (39) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. observed polymorphisms in Obp8a, Obp19a, Obp19b, and Obp19c associated with variation in olfactory responses and polymorphisms in Obp19d associated with variation in life span.
    Title: Natural variation, functional pleiotropy and transcriptional contexts of odorant binding protein genes in Drosophila melanogaster.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables odorant binding IEA
Inferred from Electronic Annotation
more info
  
enables odorant binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in sensory perception of chemical stimulus ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in sensory perception of smell IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in extracellular region ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
Odorant-binding protein 8a
Names
CG12665-PA
Obp8a-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    9214876..9215699
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_167184.2 → NP_727322.1  Odorant-binding protein 8a [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_727322.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E2D9D9, E2D9F2, E2D9H3, Q9W372
    Related
    FBpp0071242
    Conserved Domains (1) summary
    smart00708
    Location:43 → 144
    PhBP; Insect pheromone/odorant binding protein domains
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W372 Q9W372

Gene LinkOut

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