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Abcf2 ATP binding cassette subfamily F member 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 311959, updated on 27-Nov-2024

Summary

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Official Symbol
Abcf2provided by RGD
Official Full Name
ATP binding cassette subfamily F member 2provided by RGD
Primary source
RGD:1304942
See related
EnsemblRapid:ENSRNOG00000010609 AllianceGenome:RGD:1304942
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable ATP binding activity. Orthologous to several human genes including ABCF2 (ATP binding cassette subfamily F member 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Testes (RPKM 330.4), Muscle (RPKM 293.6) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Abcf2 in Genome Data Viewer
Location:
4q11
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (11485865..11500067)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (10594802..10607620)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (7122850..7135607)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene SWI/SNF related BAF chromatin remodeling complex subunit D3 Neighboring gene chondroitin polymerizing factor 2 Neighboring gene microRNA 671 Neighboring gene IQ motif containing with AAA domain 1 like Neighboring gene ankyrin repeat and SOCS box-containing 10

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
  2. Defining the membrane proteome of NK cells. Ghosh D, et al. J Mass Spectrom, 2010 Jan. PMID 19946888
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ATP binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ATP-binding cassette sub-family F member 2
Names
ATP-binding cassette, sub-family F (GCN20), member 2
ATP-binding cassette, subfamily F (GCN20), member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001398837.1 → NP_001385766.1  ATP-binding cassette sub-family F member 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000004
    Conserved Domains (1) summary
    COG0488
    Location:87 → 607
    Uup; ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]

  2. NM_001398838.1 → NP_001385767.1  ATP-binding cassette sub-family F member 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000004
    Conserved Domains (1) summary
    COG0488
    Location:86 → 606
    Uup; ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]

  3. NM_001398839.1 → NP_001385768.1  ATP-binding cassette sub-family F member 2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000004
    UniProtKB/TrEMBL
    A2VD14
    Conserved Domains (1) summary
    COG0488
    Location:84 → 604
    Uup; ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]

RNA

  1. NR_174136.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000004

  2. NR_174137.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000004

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    11485865..11500067
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006235934.5 → XP_006235996.1  ATP-binding cassette sub-family F member 2 isoform X4

    UniProtKB/TrEMBL
    A0A096MIV5
    Conserved Domains (3) summary
    cd03221
    Location:90 → 306
    ABCF_EF-3; ATP-binding cassette domain of elongation factor 3, subfamily F
    COG0488
    Location:87 → 577
    Uup; ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]
    pfam12848
    Location:300 → 386
    ABC_tran_Xtn; ABC transporter

  2. XM_063285944.1 → XP_063142014.1  ATP-binding cassette sub-family F member 2 isoform X5

  3. XM_063285945.1 → XP_063142015.1  ATP-binding cassette sub-family F member 2 isoform X6

  4. XM_039107496.2 → XP_038963424.1  ATP-binding cassette sub-family F member 2 isoform X3

    UniProtKB/TrEMBL
    A0A0G2K762
    Conserved Domains (1) summary
    COG0488
    Location:83 → 603
    Uup; ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]

  5. XM_063285946.1 → XP_063142016.1  ATP-binding cassette sub-family F member 2 isoform X7

  6. XM_006235930.5 → XP_006235992.1  ATP-binding cassette sub-family F member 2 isoform X1

    See identical proteins and their annotated locations for XP_006235992.1

    UniProtKB/TrEMBL
    A0A096MIV5
    Related
    ENSRNOP00000067893.3, ENSRNOT00000076418.4
    Conserved Domains (1) summary
    COG0488
    Location:87 → 607
    Uup; ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]

  7. XM_063285942.1 → XP_063142012.1  ATP-binding cassette sub-family F member 2 isoform X4

    Related
    ENSRNOP00000074076.3, ENSRNOT00000088399.3

  8. XM_039107495.2 → XP_038963423.1  ATP-binding cassette sub-family F member 2 isoform X2

    UniProtKB/TrEMBL
    A0A0G2K762, A2VD14
    Conserved Domains (1) summary
    COG0488
    Location:84 → 604
    Uup; ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001109666.1: Suppressed sequence

    Description
    NM_001109666.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version

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