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Mrpl35 mitochondrial ribosomal protein L35 [ Rattus norvegicus (Norway rat) ]

Gene ID: 297334, updated on 27-Nov-2024

Summary

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Official Symbol
Mrpl35provided by RGD
Official Full Name
mitochondrial ribosomal protein L35provided by RGD
Primary source
RGD:1307065
See related
EnsemblRapid:ENSRNOG00000008546 AllianceGenome:RGD:1307065
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be part of mitochondrial large ribosomal subunit. Predicted to be active in mitochondrion. Orthologous to human MRPL35 (mitochondrial ribosomal protein L35). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Heart (RPKM 277.2), Muscle (RPKM 242.2) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Mrpl35 in Genome Data Viewer
Location:
4q32
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (105424076..105431844, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (103865812..103876687, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (99738792..99749665, complement)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene lysine demethylase 3A Neighboring gene uncharacterized LOC134486590 Neighboring gene receptor accessory protein 1 Neighboring gene inner membrane mitochondrial protein Neighboring gene small nucleolar RNA, C/D box 94 Neighboring gene Pentatricopeptide repeat domain 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Structures of the human mitochondrial ribosome in native states of assembly. Brown A, et al. Nat Struct Mol Biol, 2017 Oct. PMID 28892042, Free PMC Article
  2. Structure of the large ribosomal subunit from human mitochondria. Brown A, et al. Science, 2014 Nov 7. PMID 25278503, Free PMC Article
  3. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of mitochondrial large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
large ribosomal subunit protein bL35m
Names
39S ribosomal protein L35, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106596.1 → NP_001100066.1  large ribosomal subunit protein bL35m

    See identical proteins and their annotated locations for NP_001100066.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473957
    UniProtKB/TrEMBL
    A0A8I6GL56, A6IA89
    Related
    ENSRNOP00000095450.1, ENSRNOT00000117127.2
    Conserved Domains (1) summary
    pfam01632
    Location:102 → 161
    Ribosomal_L35p; Ribosomal protein L35

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    105424076..105431844 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039107316.2 → XP_038963244.1  large ribosomal subunit protein bL35m isoform X1

    Conserved Domains (1) summary
    pfam01632
    Location:88 → 147
    Ribosomal_L35p; Ribosomal protein L35

  2. XM_039107314.2 → XP_038963242.1  large ribosomal subunit protein bL35m isoform X1

    Conserved Domains (1) summary
    pfam01632
    Location:88 → 147
    Ribosomal_L35p; Ribosomal protein L35
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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